Jan Hasselström
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View article: Incident benzodiazepine and Z-drug use and subsequent risk of alcohol- and drug-related problems: A nationwide matched cohort study with co-twin comparison
Incident benzodiazepine and Z-drug use and subsequent risk of alcohol- and drug-related problems: A nationwide matched cohort study with co-twin comparison Open
Background: Despite considerable interest in the consequences of benzodiazepine and benzodiazepine-related Z-drug (BZDR) use, little is known about whether and how initiation of BZDR treatment relates to the development of alcohol- and dru…
View article: Impact of the COVID-19 pandemic on trends in health conditions associated with alcohol among patients with hypertension in Sweden
Impact of the COVID-19 pandemic on trends in health conditions associated with alcohol among patients with hypertension in Sweden Open
Research on how the COVID-19 pandemic, societal restrictions, and healthcare services barriers have impacted patients with hypertension is limited. This study aimed to evaluate trends in alcohol-related disorders, other alcohol-associated …
View article: A machine learning tool for identifying metastatic colorectal cancer in primary care
A machine learning tool for identifying metastatic colorectal cancer in primary care Open
A machine learning method based on primary health care consultation frequency and diagnoses may be used to identify important variables for predicting presence of MCRC. Both primary health care consultations and associated diagnostic codes…
View article: Nurse‐Managed Hypertension Care in Primary Health Care Centers in Region Stockholm and Its Association With Blood Pressure Control and Key Indicators for Contractual Follow‐Up
Nurse‐Managed Hypertension Care in Primary Health Care Centers in Region Stockholm and Its Association With Blood Pressure Control and Key Indicators for Contractual Follow‐Up Open
The study aimed to investigate if primary health care centers (PHCCs) offering nurse‐managed hypertensive care differ from PHCCs with other types of hypertension care regarding blood pressure levels and other key indicators. In this cross‐…
View article: Incident benzodiazepine and Z-drug use and subsequent risk of alcohol- and drug-related problems: a nationwide matched cohort study with co-twin comparison
Incident benzodiazepine and Z-drug use and subsequent risk of alcohol- and drug-related problems: a nationwide matched cohort study with co-twin comparison Open
Background Despite considerable interest in the consequences of benzodiazepine and benzodiazepine-related Z-drug (BZDR) use, little is known about whether and how initiation of BZDR treatment contributes to the development of alcohol- and …
View article: Assessing Associations of Nurse‐Managed Hypertension Care on Pharmacotherapy, Lifestyle Counseling, and Prevalence of Comorbid Cardiometabolic Diseases in All Patients With Hypertension That Are Treated in Primary Care in Stockholm, Sweden
Assessing Associations of Nurse‐Managed Hypertension Care on Pharmacotherapy, Lifestyle Counseling, and Prevalence of Comorbid Cardiometabolic Diseases in All Patients With Hypertension That Are Treated in Primary Care in Stockholm, Sweden Open
The aim was to study if nurse‐managed hypertension care was associated with differences in pharmacotherapy, lifestyle counseling, and prevalence of comorbid cardiometabolic diseases among patients receiving care at primary health care cent…
View article: Alcohol consumption in patients with hypertension in primary care comparing Phosphatidylethanol and AUDIT – Cross-sectional study
Alcohol consumption in patients with hypertension in primary care comparing Phosphatidylethanol and AUDIT – Cross-sectional study Open
Background Hazardous alcohol use often goes unidentified in management of hypertension. The aim was to describe alcohol consumption using the alcohol biomarker Phosphatidylethanol (PEth) and the Alcohol Use Disorders Identification Test (A…
View article: Predicting new cases of hypertension in Swedish primary care with a machine learning tool
Predicting new cases of hypertension in Swedish primary care with a machine learning tool Open
This machine learning model, using prevailing recorded diagnoses within primary health care, may contribute to the identification of patients at risk of unrecognized hypertension. The added value of this predictive model beyond information…
View article: Lifestyle counseling in patients with hypertension in primary health care and its association with antihypertensive pharmacotherapy
Lifestyle counseling in patients with hypertension in primary health care and its association with antihypertensive pharmacotherapy Open
The study aimed to investigate differences in hypertensive‐ and cardio‐preventive pharmacotherapy depending on if patients with hypertension received lifestyle counseling or not, including the difference between men and women. Data from th…
View article: Correction: Lung cancer prediction using machine learning on data from a symptom e-questionnaire for never smokers, formers smokers and current smokers
Correction: Lung cancer prediction using machine learning on data from a symptom e-questionnaire for never smokers, formers smokers and current smokers Open
[This corrects the article DOI: 10.1371/journal.pone.0276703.].
View article: A Qualitative Study on Patients’ Views on Hypertension and Antihypertensive Medications
A Qualitative Study on Patients’ Views on Hypertension and Antihypertensive Medications Open
Many patients with hypertension have limited understanding of their hypertension and fear of adverse events from their antihypertensive medications. There is also room for improvement in how the patients are managed in primary health care.…
View article: GPs’ experiences of phosphatidylethanol in treatment of hypertension: a qualitative study
GPs’ experiences of phosphatidylethanol in treatment of hypertension: a qualitative study Open
Background Hazardous alcohol use increases the risk of hypertension but is underdetected in primary healthcare (PHC) patients. Use of the biomarker phosphatidylethanol (PEth), which reflects the last 2–3 weeks of alcohol consumption, is in…
View article: Validation of a diagnostic prediction tool for colorectal cancer: a case–control replication study
Validation of a diagnostic prediction tool for colorectal cancer: a case–control replication study Open
Background Early detection of colorectal cancer (CRC) is crucial for survival. Primary care, the first point of contact in most cases, needs supportive risk assessment tools. We aimed to replicate the Swedish Colorectal Cancer Risk Assessm…
View article: Physical-mental multimorbidity in a large primary health care population in Stockholm County, Sweden
Physical-mental multimorbidity in a large primary health care population in Stockholm County, Sweden Open
Physical-mental multimorbidity was common in primary care patients in Sweden, with the highest odds occurring in those who were female, younger, and/or had an alcohol abuse disorder.
View article: Identifying factors explaining practice variation in secondary stroke prevention in primary care: a cohort study based on all patients with ischaemic stroke in the Stockholm region
Identifying factors explaining practice variation in secondary stroke prevention in primary care: a cohort study based on all patients with ischaemic stroke in the Stockholm region Open
Objectives The aim of this study was to describe the practice variation in dispensation of secondary stroke preventive drugs among patients at different primary care centres (PCCs) in Stockholm region and to identify factors that may expla…
View article: Lung cancer prediction using machine learning on data from a symptom e-questionnaire for never smokers, formers smokers and current smokers
Lung cancer prediction using machine learning on data from a symptom e-questionnaire for never smokers, formers smokers and current smokers Open
Purpose The aim of the present study was to investigate the predictive ability for lung cancer of symptoms reported in an adaptive e-questionnaire, separately for never smokers, former smokers, and current smokers. Patients and methods Con…
View article: Prenatal exposure to benzodiazepines and Z-drugs in humans and risk of adverse neurodevelopmental outcomes in offspring: A systematic review
Prenatal exposure to benzodiazepines and Z-drugs in humans and risk of adverse neurodevelopmental outcomes in offspring: A systematic review Open
When used during pregnancy, benzodiazepines (BZDs) and related z-drugs could pass readily through the placenta and the foetal blood-brain barrier, where they can bind to γ-amino butyric acid (GABA) receptors in the developing foetal brain.…
View article: Person-centred care transitions for people with stroke: study protocol for a feasibility evaluation of codesigned care transition support
Person-centred care transitions for people with stroke: study protocol for a feasibility evaluation of codesigned care transition support Open
Background Care transitions following stroke should be bridged with collaboration between hospital staff and home rehabilitation teams since well-coordinated transitions can reduce death and disability following a stroke. However, health s…
View article: The impact of diabetes, education and income on mortality and cardiovascular events in hypertensive patients: A cohort study from the Swedish Primary Care Cardiovascular Database (SPCCD)
The impact of diabetes, education and income on mortality and cardiovascular events in hypertensive patients: A cohort study from the Swedish Primary Care Cardiovascular Database (SPCCD) Open
Diabetes combined with low income was associated with substantial excess risk of mortality, myocardial infarction and ischemic stroke among primary care patients with hypertension.
View article: Drug–disease interactions in Swedish senior primary care patients were dominated by non-steroid anti-inflammatory drugs and hypertension – a population-based registry study
Drug–disease interactions in Swedish senior primary care patients were dominated by non-steroid anti-inflammatory drugs and hypertension – a population-based registry study Open
DDSIs were present in every tenth older patient in primary care. Patients with cardiovascular disease receive NSAIDs to a lower extent, possibly indicating physician awareness of DDSI. Key points Evidence on the prevalence of drug-disease …
View article: An audit & feedback intervention for improved anticoagulant use in patients with atrial fibrillation in primary care
An audit & feedback intervention for improved anticoagulant use in patients with atrial fibrillation in primary care Open
BackgroundImproving use of anticoagulants in atrial fibrillation (AF) patients in primary care has proved challenging. Anticoagulants are often prescribed by primary care physicians in the long term. Suboptimal anticoagulant use may be par…
View article: The transition from hypertension to hypertensive heart disease and heart failure: the PREFERS Hypertension study
The transition from hypertension to hypertensive heart disease and heart failure: the PREFERS Hypertension study Open
Aims Despite evidence‐based therapeutic approaches, target blood pressure is obtained by less than half of patients with hypertension. Hypertension is associated with a significant risk for heart failure, in particular heart failure with p…
View article: Medication persistence to antihypertensive drug treatment – a cross-sectional study of attitudes towards hypertension and medication in persistent and non-persistent patients
Medication persistence to antihypertensive drug treatment – a cross-sectional study of attitudes towards hypertension and medication in persistent and non-persistent patients Open
Purpose: To study the differences in attitudes towards hypertension and drug treatment between patients persistent and non-persistent to antihypertensive drug treatment. Materials and methods: Cross-sectional study on patients with hyperte…
View article: General practitioners’ and nurses’ views on medication reviews and potentially inappropriate medicines in elderly patients – a qualitative study of reports by educating pharmacists
General practitioners’ and nurses’ views on medication reviews and potentially inappropriate medicines in elderly patients – a qualitative study of reports by educating pharmacists Open
GPs and nurses should participate in the construction and release of guidelines in order to increase their usability in clinical practice. Future research should analyse if alternative strategies such as condensed medical reviews and feedb…
View article: Recording a diagnosis of stroke, transient ischaemic attack or myocardial infarction in primary healthcare and the association with dispensation of secondary preventive medication: a registry-based prospective cohort study
Recording a diagnosis of stroke, transient ischaemic attack or myocardial infarction in primary healthcare and the association with dispensation of secondary preventive medication: a registry-based prospective cohort study Open
Objectives The aim of this study was to explore whether recording in primary care of a previously recorded hospital diagnosis was associated with increased patient utilisation of recommended medications. Design Registry-based prospective c…
View article: The use of a Swedish telephone medical advice service by the elderly – a population-based study
The use of a Swedish telephone medical advice service by the elderly – a population-based study Open
The high utilisation of the telephone advice service by the elderly gives the telephone advice service a unique ability to function as a gatekeeper to further healthcare. Our data suggest that with the telephone advice service's present gu…