Jan Kuta
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View article: Cyanochelin B: a cyanobacterium-produced siderophore with photolytic properties that negate iron monopolization in UV light
Cyanochelin B: a cyanobacterium-produced siderophore with photolytic properties that negate iron monopolization in UV light Open
Siderophores are low-molecular-weight compounds excreted by microorganisms to acquire iron and possibly to monopolize iron resource to achieve competitive advantage over other strains, or to trade for other substrates in mutualistic relati…
View article: Blood and cerebrospinal fluid metallomics uncover mercury, chromium, and iron alterations in <i>de novo</i> Parkinson's disease
Blood and cerebrospinal fluid metallomics uncover mercury, chromium, and iron alterations in <i>de novo</i> Parkinson's disease Open
Background Given the increasing global prevalence of Parkinson's disease (PD) and its complex etiopathogenesis, understanding the role of environmental factors is crucial. Prior investigations suggested a potential link between metal expos…
View article: Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd <sub>12</sub> L <sub>16</sub>
Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd <sub>12</sub> L <sub>16</sub> Open
The rational design and selective self‐assembly of flexible and unsymmetric ligands into large coordination complexes is an eminent challenge in supramolecular coordination chemistry. Here, we present the coordination‐driven self‐assembly …
View article: Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd <sub>12</sub> L <sub>16</sub>
Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd <sub>12</sub> L <sub>16</sub> Open
The rational design and selective self‐assembly of flexible and unsymmetric ligands into large coordination complexes is an eminent challenge in supramolecular coordination chemistry. Here, we present the coordination‐driven self‐assembly …
View article: Cyclodextrin-Based Metal–Organic Framework as an Application Platform for Bioactive Ruthenium(III) Complexes
Cyclodextrin-Based Metal–Organic Framework as an Application Platform for Bioactive Ruthenium(III) Complexes Open
Ruthenium(III) complexes are promising anticancer metallodrugs because of their antimetastatic (migrastatic) potential and significantly lower host toxicity than generally used platinum metallodrugs. On the other hand, the ruthenium(III) c…
View article: Cyanochelin B: A siderophore produced by cyanobacterium <i>Leptolyngbya</i> sp. NIES-3755 with photolytic properties that negate iron monopolization in the UV-light
Cyanochelin B: A siderophore produced by cyanobacterium <i>Leptolyngbya</i> sp. NIES-3755 with photolytic properties that negate iron monopolization in the UV-light Open
Siderophores are low-molecular-weight compounds excreted by microorganisms to facilitate iron uptake in times of its unavailability. Microbes may produce siderophores to monopolize iron and achieve competitive exclusion of other strains. A…
View article: Internal Flames: Metal(loid) Exposure Linked to Alteration of the Lipid Profile in Czech Male Firefighters (CELSPAC-FIREexpo Study)
Internal Flames: Metal(loid) Exposure Linked to Alteration of the Lipid Profile in Czech Male Firefighters (CELSPAC-FIREexpo Study) Open
Increased wildfire activity increases the demands on fire rescue services and firefighters' contact with harmful chemicals. This study aimed to determine firefighters' exposure to toxic metal(loid)s and its association with the lipid profi…
View article: Pull-down assay coupled to non-target mass spectrometry analysis as a tool to identify unknown endocrine disruptive transthyretin ligands in waste and surface water
Pull-down assay coupled to non-target mass spectrometry analysis as a tool to identify unknown endocrine disruptive transthyretin ligands in waste and surface water Open
Surface and treated wastewaters are contaminated with highly complex mixtures of micropollutants, which may cause adverse effects on aquatic biota or humans, often mediated by endocrine disruption. However, there is very limited knowledge …
View article: Proposals of guidance values for surface contamination by antineoplastic drugs based on long term monitoring in Czech and Slovak hospitals and pharmacies
Proposals of guidance values for surface contamination by antineoplastic drugs based on long term monitoring in Czech and Slovak hospitals and pharmacies Open
Introduction The exposures to hazardous antineoplastic drugs (AD) represent serious risks for health care personnel but the exposure limits are not commonly established because of the no-threshold effects (genotoxic action, carcinogenicity…
View article: Effect of titanium nanostructured surface on fibroblast behavior
Effect of titanium nanostructured surface on fibroblast behavior Open
As the consumption of implants increases, so do the requirements for individual types of implants, for example, improved biocompatibility or longevity. Therefore, the nano‐modification of the titanium surface is often chosen. The aim was t…
View article: Metals and Trace Elements in Calcified Valves in Patients with Acquired Severe Aortic Valve Stenosis: Is There a Connection with the Degeneration Process?
Metals and Trace Elements in Calcified Valves in Patients with Acquired Severe Aortic Valve Stenosis: Is There a Connection with the Degeneration Process? Open
Background. Acquired calcified aortic valve stenosis is the most common valve disease in adulthood. In the etiopathogenesis of this complex pathology, the importance of inflammation is mentioned, in which non-infectious influences represen…
View article: Polycyclic aromatic hydrocarbons (PAHs) and their alkylated, nitrated and oxygenated derivatives in the atmosphere over the Mediterranean and Middle East seas
Polycyclic aromatic hydrocarbons (PAHs) and their alkylated, nitrated and oxygenated derivatives in the atmosphere over the Mediterranean and Middle East seas Open
Polycyclic aromatic hydrocarbons (PAHs) and their alkylated (RPAHs), nitrated (NPAHs) and oxygenated (OPAHs) derivatives are air pollutants. Many of these substances are long-lived, can undergo long-range atmospheric transport and adversel…
View article: P-042 Method validation for a multi-element panel in human seminal plasma by inductively coupled plasma tandem mass spectrometry (ICP-MS/MS)
P-042 Method validation for a multi-element panel in human seminal plasma by inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) Open
Study question Can we quantitatively, accurately, and simultaneously determine concentrations of essential and toxic elements in seminal fluid? Summary answer We developed and validated a multi-element panel to quantify essential and toxic…
View article: Polycyclic aromatic hydrocarbons (PAHs) and their alkylated-, nitro- and oxy-derivatives in the atmosphere over the Mediterranean and Middle East seas
Polycyclic aromatic hydrocarbons (PAHs) and their alkylated-, nitro- and oxy-derivatives in the atmosphere over the Mediterranean and Middle East seas Open
Polycyclic aromatic hydrocarbons (PAHs), their alkylated (RPAHs), nitrated (NPAHs) and oxygenated (OPAHs) derivatives are air pollutants. Many of these substances are long-lived, can undergo long-range atmospheric transport and adversely a…
View article: Supplementary material to "Polycyclic aromatic hydrocarbons (PAHs) and their alkylated-, nitro- and oxy-derivatives in the atmosphere over the Mediterranean and Middle East seas"
Supplementary material to "Polycyclic aromatic hydrocarbons (PAHs) and their alkylated-, nitro- and oxy-derivatives in the atmosphere over the Mediterranean and Middle East seas" Open
D30 0.0 0.0 no D31 0.5 1.0 no D32 0.2 1.0 no Sample Possible contamination in % of sampling time Percentage difference of average surface PAH of "possibly contaminated" and "not contaminated" sampling time [%] Reject due to possible contam…
View article: Different trends of Cr, Fe and Zn contents in hair between obese, overweight and normal-weight men
Different trends of Cr, Fe and Zn contents in hair between obese, overweight and normal-weight men Open
Consistent with some published studies, we have found that obese men have higher chromium and iron concentrations and lower zinc concentrations in hair.
View article: Levels And Risks of Antineoplastic Drugs In Households of Oncology Patients, Hospices And Retirement Homes
Levels And Risks of Antineoplastic Drugs In Households of Oncology Patients, Hospices And Retirement Homes Open
BackgroundContamination of the indoor environment by the antineoplastic drugs (ADs) is known to pose health risks to the exposed staff in hospitals or pharmacies. ADs may also contaminate households of the patients receiving chemotherapy b…
View article: Raman Microspectroscopic Analysis of Selenium Bioaccumulation by Green Alga Chlorella vulgaris
Raman Microspectroscopic Analysis of Selenium Bioaccumulation by Green Alga Chlorella vulgaris Open
Selenium (Se) is an element with many commercial applications as well as an essential micronutrient. Dietary Se has antioxidant properties and it is known to play a role in cancer prevention. However, the general population often suffers f…
View article: Oxygenated and Nitrated Polycyclic Aromatic Hydrocarbons in Ambient Air—Levels, Phase Partitioning, Mass Size Distributions, and Inhalation Bioaccessibility
Oxygenated and Nitrated Polycyclic Aromatic Hydrocarbons in Ambient Air—Levels, Phase Partitioning, Mass Size Distributions, and Inhalation Bioaccessibility Open
Among the nitrated and oxygenated polycyclic aromatic hydrocarbons (NPAHs and OPAHs) are some of the most hazardous substances to public health, mainly because of their carcinogenicity and oxidative potential. Despite these concerns, the c…
View article: Graphene Oxide from Improved Hummers’ Method: Is This Material Suitable for Reproducible Electrochemical (Bio)Sensing?
Graphene Oxide from Improved Hummers’ Method: Is This Material Suitable for Reproducible Electrochemical (Bio)Sensing? Open
Graphene as a superior nanomaterial is currently omnipresent and electroanalytical applications are not an exception. In this contribution, its suitability for such applications was critically assessed. We synthesized graphene oxide (GO) i…
View article: Hypersensitivity to material and environmental burden as a possible cause of late complications of cardiac implantable electronic devices
Hypersensitivity to material and environmental burden as a possible cause of late complications of cardiac implantable electronic devices Open
Our findings suggest a possible relation between hypersensitivity to metals used in implantable devices or to environmental metal burden and the occurrence of their late complications.
View article: The role of Mn and Fe oxides in risk elements retention in soils under different forest types
The role of Mn and Fe oxides in risk elements retention in soils under different forest types Open
Retention of four selected risk elements (SRE) - arsen (As), cadmium (Cd), lead (Pb), zinc (Zn) - by manganese (Mn) and iron (Fe) oxides in different forest soils was investigated. The abundance of oxides and the association between oxides…
View article: Drinking water contaminants from epoxy resin-coated pipes: A field study
Drinking water contaminants from epoxy resin-coated pipes: A field study Open
Rehabilitation of aged drinking water pipes is an extensive renovation and increasingly topical in many European cities. Spray-on-lining of drinking water pipes is an alternative cost-effective rehabilitation technology in which the inside…