Jan Loskot
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View article: Combining Selective Laser Sintering and Fused Deposition Modeling of Pharmaceutical Polymers: A Novel Approach to Prepare Intestine‐Targeted Tablets
Combining Selective Laser Sintering and Fused Deposition Modeling of Pharmaceutical Polymers: A Novel Approach to Prepare Intestine‐Targeted Tablets Open
This study introduces a novel approach to prepare an intestine‐targeting transport system with a controlled drug release profile, combining two 3D printing techniques: selective laser sintering (SLS) and fused deposition modeling (FDM). Ma…
View article: Combining of spray drying and dry granulation to prepare orodispersible tablets: Influence of spray-dried particle size on tablet properties
Combining of spray drying and dry granulation to prepare orodispersible tablets: Influence of spray-dried particle size on tablet properties Open
View article: Ion-paired antibiotics in PLGA nanoparticles: improving encapsulation efficiency and musculoskeletal infection treatment
Ion-paired antibiotics in PLGA nanoparticles: improving encapsulation efficiency and musculoskeletal infection treatment Open
Many studies have shown that gentamicin (GEN) and vancomycin (VAN) are effective in the treatment of musculoskeletal infections, especially when applied locally in the form of sustained-release drug delivery systems.
View article: Degradation Behavior and Environmental Impacts of a Hemp-Containing “Eco-Friendly” Compostable Plastic in Natural Environments
Degradation Behavior and Environmental Impacts of a Hemp-Containing “Eco-Friendly” Compostable Plastic in Natural Environments Open
View article: Impact of Saharan dust on particulate matter characteristics in an urban and a natural locality in Central Europe
Impact of Saharan dust on particulate matter characteristics in an urban and a natural locality in Central Europe Open
View article: Saharan dust in Central Europe: Impact on particulate matter characteristics in an urban and a natural locality
Saharan dust in Central Europe: Impact on particulate matter characteristics in an urban and a natural locality Open
At the turn of March and April 2024, most of mainland Europe was afflicted by sand dust particles carried by wind flow from the Sahara Desert. As a result, Central Europe experienced an exceptionally high increase in air pollution. In this…
View article: A comprehensive study on the degradation process of medical-grade polydioxanone at low pH
A comprehensive study on the degradation process of medical-grade polydioxanone at low pH Open
Polydioxanone (PPDX) has gained significant attention as a biocompatible and absorbable polymer used various medical applications, such as sutures and tissue scaffolds. This research presents a thorough investigation into the degradation m…
View article: The Use of Raman Spectroscopy to Assess the Degradation of Poly(p-dioxanone) Fibre Intended for Medical Purposes
The Use of Raman Spectroscopy to Assess the Degradation of Poly(p-dioxanone) Fibre Intended for Medical Purposes Open
Raman spectroscopy can be used in chemistry not just to determine chemical composition, but also to obtain further information on the material structure. In the spectra of semi-crystalline polymers, distinct bands characteristic of the cry…
View article: The use of scanning electron microscopy and fixation methods to evaluate the interaction of blood with the surfaces of medical devices
The use of scanning electron microscopy and fixation methods to evaluate the interaction of blood with the surfaces of medical devices Open
View article: A Comprehensive Study on the Degradation Process of Medical-Grade Polydioxanone at Low pH
A Comprehensive Study on the Degradation Process of Medical-Grade Polydioxanone at Low pH Open
View article: The use of scanning electron microscopy and fixation methods to evaluate the interaction of blood with the surfaces of medical devices
The use of scanning electron microscopy and fixation methods to evaluate the interaction of blood with the surfaces of medical devices Open
Testing the hemocompatibility of medical devices after their interaction with blood entails the need to evaluate the activation of blood elements and the degree of their coagulation and adhesion to the device surface. One possible way to a…
View article: The Alphabet of Nanostructured Polypyrrole
The Alphabet of Nanostructured Polypyrrole Open
This review is devoted to polypyrrole and its morphology, which governs the electroactivity of the material. The macroscopic properties of the material are strictly relevant to microscopic ordering observed at the local level. During the s…
View article: Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy
Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy Open
View article: Influence of print speed on the microstructure, morphology, and mechanical properties of 3D-printed PETG products
Influence of print speed on the microstructure, morphology, and mechanical properties of 3D-printed PETG products Open
The presented research aimed to thoroughly investigate the effects of print speed on glycol-modified polyethylene terephthalate (PETG) printed using fused filament fabrication (FFF) technology. The printed product microstructure and morpho…
View article: Crystallization Kinetics and Structure Evolution during Annealing of Ni-Co-Mn-In Powders Obtained by Mechanical Alloying
Crystallization Kinetics and Structure Evolution during Annealing of Ni-Co-Mn-In Powders Obtained by Mechanical Alloying Open
The crystallization kinetics and structure evolution during annealing of the Ni45.5Co4.5Mn36.6In13.4 (at. %) powders produced by mechanical alloying (MA) was investigated. After 70 h and 100 h of MA, the powder consisted of a mixture of am…
View article: Preparation and advanced characterization of highly drug-loaded, 3D printed orodispersible tablets containing fluconazole
Preparation and advanced characterization of highly drug-loaded, 3D printed orodispersible tablets containing fluconazole Open
View article: Allogeneic Bone Impregnated with Biodegradable Depot Delivery Systems for the Local Treatment of Joint Replacement Infections: An In Vitro Study
Allogeneic Bone Impregnated with Biodegradable Depot Delivery Systems for the Local Treatment of Joint Replacement Infections: An In Vitro Study Open
Although progress is evident in the effective treatment of joint replacement-related infections, it still remains a serious issue in orthopedics. As an example, the local application of antibiotics-impregnated bone grafts supplies the high…
View article: Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy
Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy Open
In this study, scanning electron microscopy (SEM) was used to study the cell structure of SARS-CoV-2 infected cells. Our measurements revealed infection remodeling caused by infection, including the emergence of new specialized areas where…
View article: Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy
Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy Open
In this study, scanning electron microscopy (SEM) was used to study the cell structure of SARS-CoV-2 infected cells. Our measurements revealed infection remodeling caused by infection, including the emergence of new specialized areas where…
View article: A Complex In Vitro Degradation Study on Polydioxanone Biliary Stents during a Clinically Relevant Period with the Focus on Raman Spectroscopy Validation
A Complex In Vitro Degradation Study on Polydioxanone Biliary Stents during a Clinically Relevant Period with the Focus on Raman Spectroscopy Validation Open
Biodegradable biliary stents are promising treatments for biliary benign stenoses. One of the materials considered for their production is polydioxanone (PPDX), which could exhibit a suitable degradation time for use in biodegradable stent…
View article: Fused Deposition Modeling as a Possible Approach for the Preparation of Orodispersible Tablets
Fused Deposition Modeling as a Possible Approach for the Preparation of Orodispersible Tablets Open
Additive manufacturing technologies are considered as a potential way to support individualized pharmacotherapy due to the possibility of the production of small batches of customized tablets characterized by complex structures. We designe…
View article: Study of rheological and tableting properties of lubricated mixtures of co-processed dry binders for orally disintegrating tablets
Study of rheological and tableting properties of lubricated mixtures of co-processed dry binders for orally disintegrating tablets Open
Co-processed dry binders for ODTs are important multifunctional excipients for tablet manufacturing by direct compression. Testing their binary mixtures with lubricants is an important aspect of their use in combination with drugs. The aim…
View article: Raman Spectroscopy as a Novel Method for the Characterization of Polydioxanone Medical Stents Biodegradation
Raman Spectroscopy as a Novel Method for the Characterization of Polydioxanone Medical Stents Biodegradation Open
Polydioxanone (PPDX), as an FDA approved polymer in tissue engineering, is an important component of some promising medical devices, e.g., biodegradable stents. The hydrolytic degradation of polydioxanone stents plays a key role in the saf…
View article: ANALYSES OF WASTE PRODUCTS OBTAINED BY LASER CUTTING OF AW-3103 ALUMINIUM ALLOY
ANALYSES OF WASTE PRODUCTS OBTAINED BY LASER CUTTING OF AW-3103 ALUMINIUM ALLOY Open
In the presented research, the methods of scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction and transmission electron microscopy were applied to analyse the powder waste obtained by cutting of AW-3103 al…
View article: Analysis of Stainless Steel Waste Products Generated during Laser Cutting in Nitrogen Atmosphere
Analysis of Stainless Steel Waste Products Generated during Laser Cutting in Nitrogen Atmosphere Open
Laser cutting technology is one of the basic approaches used for thermal processing of parts fabricated from almost all engineering materials. Various types of lasers are utilized in the industry with different attendant gases such as nitr…
View article: Microstructure and Mechanical Properties of Co-Cr-Mo-Si-Y-Zr High Entropy Alloy
Microstructure and Mechanical Properties of Co-Cr-Mo-Si-Y-Zr High Entropy Alloy Open
Presented work was focused on obtaining new, up to our knowledge, non-described previously in the literature high entropy Co15Cr15Mo25Si15Y15Zr15 alloy to fill in the knowledge gap about the six-elemental alloys located in the adjacent to …
View article: Synthesis of SnSe quantum dots by successive ionic layer adsorption and reaction (SILAR) method for efficient solar cells applications
Synthesis of SnSe quantum dots by successive ionic layer adsorption and reaction (SILAR) method for efficient solar cells applications Open
© 2020 International Solar Energy Society Quantum dots (QDs) are one of the promising materials in the development of third-generation photovoltaics. QDs have the advantage of multiple exciton generation (MEG), high absorption coefficient …
View article: Innovative educational course II: Modelling of odour dispersion from agricultural biogas plants
Innovative educational course II: Modelling of odour dispersion from agricultural biogas plants Open
In recent years, the European Union is putting a growing emphasis on constructing agricultural biogas plants, especially in the Czech-Polish border region. In this region, there are large areas of agricultural land which can provide biomas…
View article: Fluctuations of Pigment’s Dipole Moment Orientations in B850 Ring from Photosynthetic Complex LH2
Fluctuations of Pigment’s Dipole Moment Orientations in B850 Ring from Photosynthetic Complex LH2 Open
Properties of light–harvesting (LH) pigment–protein complexes are strongly influenced by interactions with environment. Some of these interactions could be modeled by different types of static disorder. Slow fluctuations of bacteriochlorop…
View article: Modelling of Mercury Emissions from Large Solid Fuel Combustion and Biomonitoring in CZ-PL Border Region
Modelling of Mercury Emissions from Large Solid Fuel Combustion and Biomonitoring in CZ-PL Border Region Open
Tightening of norms for air protection leads to a development of new and significantly more effective techniques for removing particulate matter, SO x and NO x from flue gas which originates from large solid fuel combustion. Recently, it h…