Jan Roggeveld
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View article: The Risk of Microbial Transmission in Recipients of Donor Livers That Underwent Hypothermic or Normothermic Machine Perfusion
The Risk of Microbial Transmission in Recipients of Donor Livers That Underwent Hypothermic or Normothermic Machine Perfusion Open
Background. Ex situ machine perfusion is increasingly used to preserve and assess donor livers before transplantation. Compared with traditional static cold storage (SCS), machine perfusion exposes livers to an additional risk of microbial…
View article: A potential novel treatment for cirrhosis‐related ascites: Empagliflozin is safe and tolerable in advanced chronic liver disease
A potential novel treatment for cirrhosis‐related ascites: Empagliflozin is safe and tolerable in advanced chronic liver disease Open
Aims Advanced chronic liver disease and advanced chronic liver disease‐related ascites have a high mortality. The pharmacological treatment of ascites and fluid overload has changed little over time. Empagliflozin, a sodium‐glucose cotrans…
View article: Expeditious quantification of plasma tacrolimus with liquid chromatography tandem mass spectrometry in solid organ transplantation
Expeditious quantification of plasma tacrolimus with liquid chromatography tandem mass spectrometry in solid organ transplantation Open
View article: Increasing metformin concentrations and its excretion in both rat and porcine ex vivo normothermic kidney perfusion model
Increasing metformin concentrations and its excretion in both rat and porcine ex vivo normothermic kidney perfusion model Open
Introduction Metformin can accumulate and cause lactic acidosis in patients with renal insufficiency. Metformin is known to inhibit mitochondria, while renal secretion of the drug by proximal tubules indirectly requires energy. We investig…
View article: UHPLC–MS/MS Method for Iohexol Determination in Human EDTA and Lithium-Heparin Plasma, Human Urine and in Goat- and Pig EDTA Plasma
UHPLC–MS/MS Method for Iohexol Determination in Human EDTA and Lithium-Heparin Plasma, Human Urine and in Goat- and Pig EDTA Plasma Open
Aim: Iohexol plasma clearance is used as an indicator of kidney function in clinical and preclinical settings. To investigate the pharmacokinetic profile of iohexol, a rapid, simple method for measurement of iohexol in different mat…
View article: Renal Trapping in Accidental Metformin Intoxication
Renal Trapping in Accidental Metformin Intoxication Open