Jan Stašek
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View article: Perspectives of physicians and nurses on palliative and end-of-life care practices in ICU beyond the COVID-19 era: An European survey study
Perspectives of physicians and nurses on palliative and end-of-life care practices in ICU beyond the COVID-19 era: An European survey study Open
Background: The practice of end-of-life (EOL) and palliative care was modified during the coronavirus disease 2019 (COVID-19) pandemic due to several factors, often related to isolation and infection prevention measures. This study aims to…
View article: Dexamethasone doses in patients with <scp>COVID</scp>‐19 and hypoxia: <scp>A</scp> systematic review and meta‐analysis
Dexamethasone doses in patients with <span>COVID</span>‐19 and hypoxia: <span>A</span> systematic review and meta‐analysis Open
Background The optimal dose of dexamethasone for severe/critical COVID‐19 is uncertain. We compared higher versus standard doses of dexamethasone in adults with COVID‐19 and hypoxia. Methods We searched PubMed and trial registers until 23 …
View article: Update on Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Critically Ill Patients—A Narrative Review
Update on Therapeutic Drug Monitoring of Beta-Lactam Antibiotics in Critically Ill Patients—A Narrative Review Open
Beta-lactam antibiotics remain one of the most preferred groups of antibiotics in critical care due to their excellent safety profiles and their activity against a wide spectrum of pathogens. The cornerstone of appropriate therapy with bet…
View article: Cryptococcal Pneumonia: An Unusual Complication in a COVID-19 Patient
Cryptococcal Pneumonia: An Unusual Complication in a COVID-19 Patient Open
Cryptococcal superinfection is a rare but potentially fatal complication, especially if its detection and subsequent treatment are delayed. Histopathological findings of pulmonary parenchyma from a deceased patient with these complications…
View article: Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in the Czech Republic
Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in the Czech Republic Open
Background Providing palliative care, including end-of-life decisions (EOLD), seems to be modified during the COVID-19 pandemic with potential burden of moral distress (MD) to health care providers (HCPs) We seek to assess the practice of …
View article: Clinical practise of administration of systemic corticosteroids among critically ill patients with COVID-19 in the Czech Republic: survey (ASAP‑C)
Clinical practise of administration of systemic corticosteroids among critically ill patients with COVID-19 in the Czech Republic: survey (ASAP‑C) Open
CĂl studie: LĂŠÄba pacientĹŻ s tÄĹžkĂ˝m prĹŻbÄhem onemocnÄnĂ covid-19 (Coronavirus Disease 2019) kortikoidy je doporuÄena SvÄtovou zdravotnickou organizacĂ na zĂĄkladÄ vĂ˝sledkĹŻ studie RECOVERY. StĂĄle vĹĄak existuje mnoho otĂĄz…
View article: Additional file 2 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic
Additional file 2 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic Open
Additional file 2 Appendix 2. Complete analysis.
View article: Additional file 1 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic
Additional file 1 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic Open
Additional file 1. Appendix 1. Questionnaire.
View article: Additional file 3 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic
Additional file 3 of Palliative care practice and moral distress during COVID-19 pandemic (PEOpLE-C19 study): a national, cross-sectional study in intensive care units in the Czech Republic Open
Additional file 3 Appendix 3. Source data.
View article: Effect of Dexamethasone In Patients With ARDS And COVID-19 (REMED Trial) – Study Protocol For A Prospective, Multi-Centre, Open-Label, Parallel-Group, Randomized Controlled Trial
Effect of Dexamethasone In Patients With ARDS And COVID-19 (REMED Trial) – Study Protocol For A Prospective, Multi-Centre, Open-Label, Parallel-Group, Randomized Controlled Trial Open
Background : Since December 2019, SARS-Co-2 virus has infected millions of people worldwide. In patients with COVID-19 pneumonia in need for oxygen therapy or mechanical ventilation, dexamethasone 6 mg per day is currently recommended. How…
View article: Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial
Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial Open
ObjectivesThe primary objective of this study is to test the hypothesis that administration of dexamethasone 20 mg is superior to a 6 mg dose in adult patients with moderate or severe ARDS due to confirmed COVID-19. The secondary objective…
View article: Epidemiology of hospital-acquired pneumonia: Results of a Central European multicenter, prospective, observational study compared with data from the European region
Epidemiology of hospital-acquired pneumonia: Results of a Central European multicenter, prospective, observational study compared with data from the European region Open
The present study was the first to collect multicenter data on the epidemiology of HAP in the Central European Region, with respect to the incidence of etiologic agents causing HAP. It was concerned with relationships between 30-day patien…