Janani Sambath
YOU?
Author Swipe
View article: Liquid biopsy- A pivotal test to help navigate clinical decisions at a precision center in India!
Liquid biopsy- A pivotal test to help navigate clinical decisions at a precision center in India! Open
Liquid biopsy, specifically circulating tumor DNA (ctDNA) analysis, has emerged as a transformative tool in precision oncology, providing real-time, minimally invasive characterizations of the tumor and tumor dynamics. While tissue biopsy …
View article: Exceptional Response to Immunotherapy-based Treatment in Compound <i>EGFR</i> -Mutated Oligometastatic Pulmonary Sarcomatoid Carcinoma: A Case Report
Exceptional Response to Immunotherapy-based Treatment in Compound <i>EGFR</i> -Mutated Oligometastatic Pulmonary Sarcomatoid Carcinoma: A Case Report Open
Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive subtype of non–small cell lung cancer (NSCLC) with limited treatment options and poor prognosis. EGFR mutations generally respond to tyrosine kinase inhibitors (TKIs)-based tar…
View article: Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin Open
Preservation of a small population of cancer stem cells (CSCs) within a heterogeneous carcinoma serves as a paradigm to understand how select cells in a tissue maintain their undifferentiated status. In both embryogenesis and cancer, Snail…
View article: Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach Open
View article: Addendum: A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer
Addendum: A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer Open
View article: Addendum: Liquid biopsy and multi-analyte testing guided treatment of <i>HER2</i> positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy
Addendum: Liquid biopsy and multi-analyte testing guided treatment of <i>HER2</i> positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy Open
View article: Additional file 4 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Additional file 4 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach Open
Additional file 4: Table S3. Relative expression of Epithelial and mesenchymal marker proteins across cell lines.
View article: Additional file 2 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Additional file 2 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach Open
Additional file 2: Table S1. List of EMT-related proteins and peptides selected for PRM assays development.
View article: Additional file 3 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach
Additional file 3 of Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using parallel reaction monitoring-based targeted proteomics approach Open
Additional file 3: Table S2. List of EMT-related proteins and limit of detection and limit of quantitation values.
View article: Circulating markers in metastatic cancer: new perspectives
Circulating markers in metastatic cancer: new perspectives Open
IMR Press is a leading publisher of open access peer-reviewed biomedical and life sciences journals. We aim to facilitate the dissemination of high-quality research in the area of biomedical science. With a long tradition and wide readersh…
View article: Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of the matricellular protein Mindin
Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of the matricellular protein Mindin Open
Summary Intratumoral heterogeneity poses a major challenge in designing effective anti-cancer strategies. Accumulating evidence suggests that this heterogeneity arises from cancer stem cells (CSCs) that also drives tumor aggressiveness and…
View article: Excellent Response With Alpelisib and Bicalutamide for Advanced Salivary Duct Carcinoma With PIK3CA Mutation and High Androgen Receptor Expression—A Case Report
Excellent Response With Alpelisib and Bicalutamide for Advanced Salivary Duct Carcinoma With PIK3CA Mutation and High Androgen Receptor Expression—A Case Report Open
View article: A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer
A case report of androgen receptor inhibitor therapy in recurrent high-grade serous ovarian cancer Open
Ovarian cancer is common gynaecological malignancy and a leading cause of death among women. Despite the advances in treatment strategies, majority of patients present with recurrence after first- or second-line treatment. Targeted therapy…
View article: Liquid biopsy and multi-analyte testing guided treatment of <i>HER2</i> positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy
Liquid biopsy and multi-analyte testing guided treatment of <i>HER2</i> positive periampullary adenocarcinoma with durable complete response after trastuzumab based therapy Open
Periampullary adenocarcinomas are rare neoplasm that originates from the pancreatic head, the ampulla of vater, the distal bile duct or the duodenum. Surgical resection followed by adjuvant therapy is considered as the standard of care tre…
View article: Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers
Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers Open
Tumor heterogeneity attributes substantial challenges in determining the treatment regimen. Along with the conventional treatment, such as chemotherapy and radiotherapy, targeted therapy has greater impact in cancer management. Owing to th…
View article: A commentary on outcomes with liquid biopsy to determine the epidermal growth factor receptor mutation status in poor performance status, biopsy-ineligible, advanced non-small cell lung cancer patients
A commentary on outcomes with liquid biopsy to determine the epidermal growth factor receptor mutation status in poor performance status, biopsy-ineligible, advanced non-small cell lung cancer patients Open