Jandos Amankulov
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View article: ANALYSIS OF EPIDEMIOLOGICAL INDICATORSOF BREAST CANCER IN THE ALMATY REGIONIN 2015-2024
ANALYSIS OF EPIDEMIOLOGICAL INDICATORSOF BREAST CANCER IN THE ALMATY REGIONIN 2015-2024 Open
Relevance: Breast cancer (BC) is the most common form of malignant neoplasm among women worldwide. In 2020, 2.3 million new cases and about 685,000 deaths were registered. More than 80% of the cases are women over 50. Developing countries …
View article: Brief Report - First Central Asian Forum on Lung Cancer
Brief Report - First Central Asian Forum on Lung Cancer Open
View article: An Anti-HIV Drug Is Highly Effective Against SARS-CoV-2 In Vitro and Has Potential Benefit for Long COVID Treatment
An Anti-HIV Drug Is Highly Effective Against SARS-CoV-2 In Vitro and Has Potential Benefit for Long COVID Treatment Open
The persistent evolution of SARS-CoV-2 necessitates novel antiviral strategies. This study evaluated the anti-HIV prodrugs tenofovir disoproxil fumarate (TDF) and tenofovir alafenamide (TAF) for repurposing against SARS-CoV-2, assessing ke…
View article: BRCA-negative high-grade serous ovarian cancer with recurrent progression: A clinical case
BRCA-negative high-grade serous ovarian cancer with recurrent progression: A clinical case Open
View article: Features of the TNM-9 classification for lung cancer and integration of TNM-8 limitations
Features of the TNM-9 classification for lung cancer and integration of TNM-8 limitations Open
View article: BRCA-NEGATIVE HIGH-GRADE SEROUS OVARIANCANCER WITH RECURRENT PROGRESSION:A CLINICAL CASE
BRCA-NEGATIVE HIGH-GRADE SEROUS OVARIANCANCER WITH RECURRENT PROGRESSION:A CLINICAL CASE Open
Introduction: High-grade serous ovarian cancer (HGSOC) is characterized by pronounced genomic instability, frequent mutations in BRCA1/2 genes, and high clinical and molecular heterogeneity. In some patients, the disease is accompanied by …
View article: FEATURES OF THE TNM-9 CLASSIFICATION FOR LUNG CANCER AND INTEGRATIONOF TNM-8 LIMITATIONS
FEATURES OF THE TNM-9 CLASSIFICATION FOR LUNG CANCER AND INTEGRATIONOF TNM-8 LIMITATIONS Open
Relevance: Lung cancer ranks among the leading causes of morbidity and mortality in oncological diseases both in Kazakhstan and worldwide. Accurate tumor staging is crucial for choosing patient management strategies considering the continu…
View article: WITHDRAWN: High Diagnostic Performance of 68Ga-FAPI-based Techniques in Female Cancer Detection: Systematic Review and Meta-Analysis
WITHDRAWN: High Diagnostic Performance of 68Ga-FAPI-based Techniques in Female Cancer Detection: Systematic Review and Meta-Analysis Open
The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
View article: EFFICACY OF ERYTHROPOIETIN IN THE CORRECTION OF ANEMIA IN ONCOLOGY PATIENTS UNDERGOING CHEMOTHERAPY
EFFICACY OF ERYTHROPOIETIN IN THE CORRECTION OF ANEMIA IN ONCOLOGY PATIENTS UNDERGOING CHEMOTHERAPY Open
Relevance: Anemia is a common complication in oncology patients, reducing their quality of life and potentially decreasing the effectiveness of antitumor therapy. Its prevalence among patients with solid tumors reaches 40%, and during chem…
View article: BRCA-ASSOCIATED OVARIAN CANCER: EXPERIENCE PERSONALIZED TREATMENT. A CLINICAL CASE
BRCA-ASSOCIATED OVARIAN CANCER: EXPERIENCE PERSONALIZED TREATMENT. A CLINICAL CASE Open
Relevance: Ovarian cancer is one of the deadliest gynecological tumors, claiming the lives of thousands of women every year. Late diagnosis (more than 70% of cases at stage III-IV) is due to the absence of specific symptoms and low screeni…
View article: Multi-Task Attention-Guided Deep Learning for Simultaneous Breast Cancer Detection and Density Estimation in Mammography
Multi-Task Attention-Guided Deep Learning for Simultaneous Breast Cancer Detection and Density Estimation in Mammography Open
Early detection of breast cancer is critical for improving patient outcomes, and deep learning (DL) has shown promise in mammographic analysis. However, many existing systems tackle a single task (e.g., malignancy classification) and provi…
View article: Efficient MedSAMs: Segment Anything in Medical Images on Laptop
Efficient MedSAMs: Segment Anything in Medical Images on Laptop Open
Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…
View article: WITHDRAWN: High Diagnostic Performance of 68Ga-FAPI-based Techniques in Female Cancer Detection: Systematic Review and Meta-Analysis
WITHDRAWN: High Diagnostic Performance of 68Ga-FAPI-based Techniques in Female Cancer Detection: Systematic Review and Meta-Analysis Open
Positron emission tomography (PET) imaging techniques combined with computed tomography (PET/CT) or magnetic-resonance imaging (PET/MRI) have been developed in the last decades to improve primary diagnosis, staging, restaging, planning rad…
View article: Enhancing Breast Cancer Detection with Dimensionality Reduction Techniques: A Study Using PCA and LDA on Wisconsin Breast Cancer Data
Enhancing Breast Cancer Detection with Dimensionality Reduction Techniques: A Study Using PCA and LDA on Wisconsin Breast Cancer Data Open
View article: APPLICATION OF 68GA-FAPI PET/CT IN CLINICAL PRACTICE – PERSPECTIVES FOR MALIGNANT TUMOR IMAGING: A LITERATURE REVIEW
APPLICATION OF 68GA-FAPI PET/CT IN CLINICAL PRACTICE – PERSPECTIVES FOR MALIGNANT TUMOR IMAGING: A LITERATURE REVIEW Open
Relevance: The incidence of malignant neoplasms of various localizations is growing worldwide and in Kazakhstan. The mortality rate from oncological diseases is also alarmingly high. To facilitate early diagnosis and optimal therapy, scien…
View article: APPLICATION OF 68GA-FAPI PET/CT IN CLINICAL PRACTICE – PERSPECTIVES FORMALIGNANT TUMOR IMAGING:A LITERATURE REVIEW
APPLICATION OF 68GA-FAPI PET/CT IN CLINICAL PRACTICE – PERSPECTIVES FORMALIGNANT TUMOR IMAGING:A LITERATURE REVIEW Open
Relevance: The incidence of malignant neoplasms of various localizations is growing worldwide and in Kazakhstan. The mortality rate from oncological diseases is also alarmingly high. To facilitate early diagnosis and optimal therapy, scien…
View article: ASSOCIATION OF NATURAL KILLER CELLS ACTIVITY WITH THE INCIDENCEOF COLORECTAL NEOPLASIA AT SCREENING
ASSOCIATION OF NATURAL KILLER CELLS ACTIVITY WITH THE INCIDENCEOF COLORECTAL NEOPLASIA AT SCREENING Open
Relevance: Increased natural killer cells (NK cells) activity is associated with reduced colorectal cancer (CRC) risk. Previously published studies examined the association of NK cells and CRC prevalence in individuals at high cancer risk.…
View article: THE CURRENT ROLE OF MULTIPARAMETRIC MRI IN THE DIAGNOSIS OF PROSTATE CANCER:A LITERATURE REVIEW
THE CURRENT ROLE OF MULTIPARAMETRIC MRI IN THE DIAGNOSIS OF PROSTATE CANCER:A LITERATURE REVIEW Open
Relevance: Multiparametric MRI (mpMRI) is one of the main methods for diagnosing prostate cancer (PCa). Although mpMRI has been adopted into routine urological and oncological practice in a few short years, there are conflicting views on t…
View article: Lung Cancer Screening With Low-dose Chest Computed Tomography: Experience From Radon-contaminated Regions in Kazakhstan
Lung Cancer Screening With Low-dose Chest Computed Tomography: Experience From Radon-contaminated Regions in Kazakhstan Open
Objectives: The aim of this study was to present the baseline results of a pilot project conducted to evaluate the effectiveness of lung cancer screening using low-dose chest computed tomography (CT) in regions with excessive radon levels …
View article: PET/CT IN ASSESSING THE LYMPHOMA RESPONSETO TREATMENT
PET/CT IN ASSESSING THE LYMPHOMA RESPONSETO TREATMENT Open
Relevance: PET/CT has become an integral part of the diagnostic algorithm in lymphoma patients since lymphomas actively accumulate 18F-FDG. The high accuracy of PET/CT in patients with certain lymphoma types allows effective use of this me…
View article: COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASSOCIATED WITH LUNG CANCER
COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASSOCIATED WITH LUNG CANCER Open
Relevance: Chronic obstructive pulmonary disease (COPD) associated with lung can-cer is common in smoking patients. Computed tomography (CT) is vital in detecting lung cancer, assessing regional lung parenchymal destruction, and airway rem…
View article: COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASEASSOCIATED WITH LUNG CANCER
COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASEASSOCIATED WITH LUNG CANCER Open
Relevance: Chronic obstructive pulmonary disease (COPD) associated with lung cancer is common in smoking patients. Computed tomography (CT) is vital in detecting lung cancer, assessing regional lung parenchymal destruction, and airway remo…
View article: PET/CT IN ASSESSING THE LYMPHOMA RESPONSE TO TREATMENT
PET/CT IN ASSESSING THE LYMPHOMA RESPONSE TO TREATMENT Open
Relevance: PET/CT has become an integral part of the diagnostic algorithm in lymphoma patients since lymphomas actively accumulate 18F-FDG. The high accuracy of PET/CT in patients with certain lymphoma types allows effective use of this me…
View article: Referee report. For: Predictive value of 18F-fluorodeoxyglucose accumulation in visceral fat activity to detect colorectal cancer metastases (prospective observational cohort study) [version 1; peer review: 1 approved]
Referee report. For: Predictive value of 18F-fluorodeoxyglucose accumulation in visceral fat activity to detect colorectal cancer metastases (prospective observational cohort study) [version 1; peer review: 1 approved] Open
View article: Natural killer cell activity level in colorectal cancer screening in an average risk population
Natural killer cell activity level in colorectal cancer screening in an average risk population Open
Introduction Increased natural killer cell activity (NKCA) is linked to reduced risk of colorectal cancer (CRC). Several prior studies have investigated the association of NKCA and the incidence of CRC in high-risk subjects. The aim of our…
View article: Colorectal Cancer Screening with Computed Tomography Colonography: Single Region Experience in Kazakhstan
Colorectal Cancer Screening with Computed Tomography Colonography: Single Region Experience in Kazakhstan Open
Background/Aims: The aim of our study was to determine the efficacy of computed tomography colonography (CTC) in screening for colorectal cancer (CRC).Methods: A total of 612 females and 588 males aged 45 to 75 years were enrolled in CTC s…
View article: Single-centre evaluation and staging of rectal carcinoma on a 3-Tesla magnetic resonance imaging and correlation with histological profile
Single-centre evaluation and staging of rectal carcinoma on a 3-Tesla magnetic resonance imaging and correlation with histological profile Open
Introduction To assess magnetic resonance imaging (MRI) features of rectal carcinoma in correlation with pathology, and to evaluate the diagnostic accuracy of 3-Tesla MRI. Material and methods A total of 86 patients were included. 3T MR im…
View article: Contrast-enhanced spectral mammography without and with a delayed image for diagnosing malignancy among mass lesions in dense breast
Contrast-enhanced spectral mammography without and with a delayed image for diagnosing malignancy among mass lesions in dense breast Open
CESM is sensitive for the differential diagnosis of breast lesions. CESM with delayed image has higher specificity than CESM without delayed image. Delayed images with plateau and washout are typical for malignancy.
View article: Treatment stratification of non-Hodgkin large B-cell lymphoma patients based on the identification of mutational c-MYC gene
Treatment stratification of non-Hodgkin large B-cell lymphoma patients based on the identification of mutational c-MYC gene Open