Jane Bulger
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View article: ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes
ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes Open
Published Version: This article has been peer-reviewed and published in Alzheimer’s & Dementia. Please cite the published version:Fonseca LM, Beeri MS, Hawks ZW, Jung L, Cleveland M, Delgado N, Bulger J, Grinspoon E, Janess K, Sliwinsk…
View article: Cognitive vulnerability to glucose fluctuations: A digital phenotype of neurodegeneration
Cognitive vulnerability to glucose fluctuations: A digital phenotype of neurodegeneration Open
INTRODUCTION Cognition is reduced at low and high glucose, reflecting cognitive vulnerability to glucose (CVG) fluctuations. The impact of glucose fluctuations on the aging brain remains unclear. We examined whether CVG is associated with …
View article: ATN plasma biomarkers and digital cognitive performance in adults with type 1 diabetes: data from the GluCog study
ATN plasma biomarkers and digital cognitive performance in adults with type 1 diabetes: data from the GluCog study Open
Background Highly specific ATN plasma biomarker assays for neurodegenerative diseases have been developed, but their associations with cognition vary in different populations. Kidney disease, common in diabetes, may decrease the predictive…
View article: Associations of plasma biomarkers of neurodegeneration with characteristics related to type 1 diabetes
Associations of plasma biomarkers of neurodegeneration with characteristics related to type 1 diabetes Open
Background Cognitive dysfunction is more common in individuals with type 1 diabetes (T1D) compared to the general population. Blood‐based biomarkers are accurate in identifying early signs of neurodegeneration. However, studies using these…
View article: ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes
ATN blood biomarkers are related to digital cognitive assessment in type 1 diabetes Open
INTRODUCTION Associations between amyloid‐tau‐neurodegeneration (ATN) plasma biomarkers and cognition have not been characterized in adults with type 1 diabetes (T1D). METHODS Using data from participants in the Glycemic Variability and Fl…
View article: Psychosocial Factors and Glycemic Control in Young Adults With Youth-Onset Type 2 Diabetes
Psychosocial Factors and Glycemic Control in Young Adults With Youth-Onset Type 2 Diabetes Open
Importance Youth-onset type 2 diabetes is associated with poor glycemic control and early onset of complications. Identification of psychosocial factors associated with poor glycemic control is needed to inform efficacious interventions. O…
View article: Plasma Alzheimer’s disease biomarkers and intraindividual cognitive variability measured by ecological momentary assessment in adults with type 1 diabetes
Plasma Alzheimer’s disease biomarkers and intraindividual cognitive variability measured by ecological momentary assessment in adults with type 1 diabetes Open
Background Older adults with type 1 diabetes (T1D) have elevated risk of Alzheimer’s disease and related dementias (ADRD) compared to non‐diabetic controls. Because of oscillations in blood glucose, individuals with T1D are also prone to p…
View article: 4 Associations Between Glycemia and Cognitive Performance in Adults with Type 1 Diabetes (T1D) using Continuous Glucose Monitoring (CGM) and Ecological Momentary Assessment (EMA)
4 Associations Between Glycemia and Cognitive Performance in Adults with Type 1 Diabetes (T1D) using Continuous Glucose Monitoring (CGM) and Ecological Momentary Assessment (EMA) Open
Objective: Despite associations between hypoglycemia and cognitive performance using cross-sectional and experimental methods (e.g., Insulin clamp studies), few studies have evaluated this relationship in a naturalistic setting. This pilot…
View article: Antihypertensive and Lipid-Lowering Medication Adherence in Young Adults With Youth-Onset Type 2 Diabetes
Antihypertensive and Lipid-Lowering Medication Adherence in Young Adults With Youth-Onset Type 2 Diabetes Open
Importance Youth-onset type 2 diabetes is associated with early development of chronic complications. Treatment of elevated blood pressure (BP), nephropathy, and dyslipidemia are critical to reduce morbidity. Data are needed on adherence t…
View article: Dynamic associations between glucose and ecological momentary cognition in Type 1 Diabetes
Dynamic associations between glucose and ecological momentary cognition in Type 1 Diabetes Open
Type 1 diabetes (T1D) is a chronic condition characterized by glucose fluctuations. Laboratory studies suggest that cognition is reduced when glucose is very low (hypoglycemia) and very high (hyperglycemia). Until recently, technological l…
View article: Glycemic Variability and Fluctuations in Cognitive Status in Adults With Type 1 Diabetes (GluCog): Observational Study Using Ecological Momentary Assessment of Cognition
Glycemic Variability and Fluctuations in Cognitive Status in Adults With Type 1 Diabetes (GluCog): Observational Study Using Ecological Momentary Assessment of Cognition Open
Background Individuals with type 1 diabetes represent a population with important vulnerabilities to dynamic physiological, behavioral, and psychological interactions, as well as cognitive processes. Ecological momentary assessment (EMA), …
View article: Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial
Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial Open
OBJECTIVE Very young children with type 1 diabetes often struggle to achieve glycemic targets, putting them at risk for long-term complications and creating an immense management burden for caregivers. We conducted the first evaluation of …
View article: The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange
The Contemporary Prevalence of Diabetic Neuropathy in Type 1 Diabetes: Findings From the T1D Exchange Open
OBJECTIVE To evaluate the contemporary prevalence of diabetic peripheral neuropathy (DPN) in participants with type 1 diabetes in the T1D Exchange Clinic Registry throughout the U.S. RESEARCH DESIGN AND METHODS DPN was assessed with the Mi…
View article: Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries
Longitudinal Changes in Continuous Glucose Monitoring Use Among Individuals With Type 1 Diabetes: International Comparison in the German and Austrian DPV and U.S. T1D Exchange Registries Open
Continuous glucose monitoring (CGM) has been demonstrated in randomized trials to improve glucose control in patients with type 1 diabetes (1), but until recently only a minority of participants in the German/Austrian Diabetes Patienten Ve…