Jane McClements
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View article: Current Practice and Outcomes of Patients Undergoing Surgical Resection for Renal Cell Metastases to the Pancreas in Northern Ireland.
Current Practice and Outcomes of Patients Undergoing Surgical Resection for Renal Cell Metastases to the Pancreas in Northern Ireland. Open
This case series supports the role of pancreatic resection in patients with metastatic RCC, with acceptable rates of morbidity and mortality and favourable patient outcomes. The long DFI between nephrectomy and pancreatic metastases highli…
View article: Variation in treatment of intrahepatic cholangiocarcinoma: a nationwide multicentre study
Variation in treatment of intrahepatic cholangiocarcinoma: a nationwide multicentre study Open
Journal Article Variation in treatment of intrahepatic cholangiocarcinoma: a nationwide multicentre study Get access Jane McClements, Jane McClements Department of HPB Surgery, Nottingham University Hospitals NHS Trust, Nottingham, UK Sear…
View article: SP2.2 Time to Pancreaticoduodenectomy in a Regional Hepatobiliary Unit in the COVID recovery era
SP2.2 Time to Pancreaticoduodenectomy in a Regional Hepatobiliary Unit in the COVID recovery era Open
Aims To assess factors influencing time from multidisciplinary (MDT) discussion to surgery for patients undergoing Whipple’s resection for malignant disease in a regional HPB unit. Methods Patients who underwent Whipple’s resection for cho…
View article: Fundamental control of grade‐specific colorectal cancer morphology by Src regulation of ezrin–centrosome engagement
Fundamental control of grade‐specific colorectal cancer morphology by Src regulation of ezrin–centrosome engagement Open
The phenotypic spectrum of colorectal cancer (CRC) is remarkably diverse, with seemingly endless variations in cell shape, mitotic figures and multicellular configurations. Despite this morphological complexity, histological grading of col…
View article: To explore the intake, knowledge and perceived perceptions of caffeine consumption on performance within a population of elite hockey players
To explore the intake, knowledge and perceived perceptions of caffeine consumption on performance within a population of elite hockey players Open
Background: Previous literature has debated the effectiveness of caffeine as a stimulant on
\nspecific aspects of an athlete’s performance. Although associations have been drawn between
\ncaffeine consumption and performance enhancement in…
View article: Protein kinase C zeta suppresses low‐ or high‐grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring
Protein kinase C zeta suppresses low‐ or high‐grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring Open
Histological grading provides prognostic stratification of colorectal cancer (CRC) by scoring heterogeneous phenotypes. Features of aggressiveness include aberrant mitotic spindle configurations, chromosomal breakage, and bizarre multicell…
View article: Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype
Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype Open
Development of cribriform morphology (CM) heralds malignant change in human colon but lack of mechanistic understanding hampers preventive therapy. This study investigated CM pathobiology in three-dimensional (3D) Caco-2 culture models of …