Jane Nakibuuka
YOU?
Author Swipe
View article: A 6-month, prospective randomized controlled trial of the TargetEd MAnageMent (TEAM) intervention vs. enhanced treatment as usual among Ugandans at risk for stroke
A 6-month, prospective randomized controlled trial of the TargetEd MAnageMent (TEAM) intervention vs. enhanced treatment as usual among Ugandans at risk for stroke Open
Background Among low and middle-income countries, especially in Sub-Saharan Africa, the stroke burden is severe, with increasing trends in stroke incidence, prevalence, and mortality. Aims This 6-month, prospective randomized controlled tr…
View article: Immediate Newborn Outcomes of Early Neonates Born to Mothers Who Received Magnesium Sulphate During Intrapartum at Kawempe National Referral Hospital- Uganda.
Immediate Newborn Outcomes of Early Neonates Born to Mothers Who Received Magnesium Sulphate During Intrapartum at Kawempe National Referral Hospital- Uganda. Open
Background: Magnesium sulphate (MgSO4) is a drug used to prevent and treat preeclampsia with severe features (PEC) and eclampsia in pregnant women. MgSO4 is also known to readily cross the placenta, fetal membranes and into the fetus and a…
View article: Characterizing stroke presenting to a regional referral hospital before and during the COVID-19 pandemic in Uganda: a retrospective analysis
Characterizing stroke presenting to a regional referral hospital before and during the COVID-19 pandemic in Uganda: a retrospective analysis Open
Introduction Stroke, a leading cause of global morbidity and mortality, disproportionately impacts low and middle-income countries, particularly in sub-Saharan Africa (SSA) which reports the highest stroke burden. The COVID-19 pandemic fur…
View article: Demographics and Clinical Correlates of Blood Pressure Among Ugandans at Risk for Stroke
Demographics and Clinical Correlates of Blood Pressure Among Ugandans at Risk for Stroke Open
View article: Administration patterns of magnesium sulphate for women with preeclampsia and immediate newborn outcomes in Kawempe National Referral Hospital-Uganda: a cohort study
Administration patterns of magnesium sulphate for women with preeclampsia and immediate newborn outcomes in Kawempe National Referral Hospital-Uganda: a cohort study Open
Timely administration of the first maintenance dose of MgSO4 decreases the likelihood of low Apgar score at 5 min and NICU admission in newborns, and most NICU admissions were due to respiratory distress and preterm delivery.
View article: Characteristics and outcomes of patients admitted to intensive care units in Uganda: a descriptive nationwide multicentre prospective study
Characteristics and outcomes of patients admitted to intensive care units in Uganda: a descriptive nationwide multicentre prospective study Open
View article: Stroke Recurrence Rate and Risk Factors Among Stroke Survivors in Sub-Saharan Africa: A Systematic Review
Stroke Recurrence Rate and Risk Factors Among Stroke Survivors in Sub-Saharan Africa: A Systematic Review Open
This systematic review is an update and summary of the available literature on stroke recurrence within sub-Saharan Africa. Further studies are warranted to assess the outcomes and burden of stroke recurrence in SSA.
View article: Evidence-Supported Interventions for Reducing Secondary Stroke Risk in Sub-Saharan Africa: A Systematic Review
Evidence-Supported Interventions for Reducing Secondary Stroke Risk in Sub-Saharan Africa: A Systematic Review Open
The study set out to perform a systematic literature review of evidence-based interventions that target the reduction of secondary stroke risk in Africa. The review analyzed longitudinal intervention studies conducted in Sub-Saharan Africa…
View article: Prevalence and factors associated with pre-hospital delay among acute stroke patients at Mulago and Kiruddu national referral hospitals, Kampala: a cross-sectional study
Prevalence and factors associated with pre-hospital delay among acute stroke patients at Mulago and Kiruddu national referral hospitals, Kampala: a cross-sectional study Open
Background Despite advancements in acute stroke care, acute stroke patients present late for care resulting in high mortality and poor functional outcomes. This study determined the prevalence of pre-hospital delay and associated factors a…
View article: Blood pressure variability and early neurological outcomes in acute and subacute stroke in Southwestern Uganda
Blood pressure variability and early neurological outcomes in acute and subacute stroke in Southwestern Uganda Open
Exponential increase in Blood Pressure Variability (BPV) and stroke severity scale were independently associated with early mortality among all stroke patients in our study. We recommend future studies to evaluate whether controlling BPV a…
View article: 4 SCALE – critical care: collaborative leadership for improving health
4 SCALE – critical care: collaborative leadership for improving health Open
Context The SCALE critical care project is a collaborative health workforce capacity and educational development initiative, between the Ministry of Health Uganda, and the NHS in the UK. The clinical leads are consultants in Anaesthesia an…
View article: Poor Seizure Control Among Children Attending a Tertiary Hospital in South Western Uganda – A Retrospective Study
Poor Seizure Control Among Children Attending a Tertiary Hospital in South Western Uganda – A Retrospective Study Open
Seizure control among CWE receiving ASMs at MRRH remains poor. Efforts geared to addressing seizure control and optimizing drugs are needed, especially among children with comorbidities, those with history of birth asphyxia, and adolescent…
View article: Respiratory Support Techniques for COVID-19-Related ARDS in a Sub-Saharan African Country
Respiratory Support Techniques for COVID-19-Related ARDS in a Sub-Saharan African Country Open
View article: Carotid Atherosclerosis and its Correlation with ApoB/ApoA-I and Non-HDL-c/HDL-c Ratios among Adults with Type 2 Diabetes: A Cross-Sectional Study in Southwestern Uganda
Carotid Atherosclerosis and its Correlation with ApoB/ApoA-I and Non-HDL-c/HDL-c Ratios among Adults with Type 2 Diabetes: A Cross-Sectional Study in Southwestern Uganda Open
Background : Type 2 diabetes mellitus (T2DM) poses an increased risk for cardiovascular disease (CVD) through atherosclerosis. The apolipoprotein B (apoB)/apolipoprotein A-I (apoA-I) (ApoB/ApoA-I) ratio is a powerful predictor of atheroscl…
View article: Co-infections among COVID-19 Patients in Ugandan Intensive Care Units
Co-infections among COVID-19 Patients in Ugandan Intensive Care Units Open
Background: The pandemic of COVID-19 has led to an upsurge of critically ill patients requiring advanced life support. Bacteria and fungi have been isolated as etiological agents for co-infections among COVID-19 patients in the intensive c…
View article: Building Critical Care Capacity in a Low-Income Country
Building Critical Care Capacity in a Low-Income Country Open
View article: Stroke in young adults, stroke types and risk factors: a case control study
Stroke in young adults, stroke types and risk factors: a case control study Open
View article: Burden and bacteriological profile of sepsis among adult medical emergencies presenting to a national referral hospital in Kampala, Uganda
Burden and bacteriological profile of sepsis among adult medical emergencies presenting to a national referral hospital in Kampala, Uganda Open
Introduction Sepsis, defined as life-threatening organ dysfunction due to dysregulated host response to infection can result from any infection. In 2017, an estimated 48.9 million incident cases of sepsis and 11.8 million sepsis-related de…
View article: Seizure Control Among Children on Anti-epileptic Drugs at a Tertiary Hospital in South Western Uganda- A Retrospective Cohort Study
Seizure Control Among Children on Anti-epileptic Drugs at a Tertiary Hospital in South Western Uganda- A Retrospective Cohort Study Open
Background: Epilepsy is the commonest neurological disease globally. Up to 70% of the people with epilepsy can attain good seizure control with appropriate timely diagnosis and treatment, hence better quality of life. However, this is not …
View article: Safety and efficacy of hydroxychloroquine for treatment of non-severe COVID-19 among adults in Uganda: a randomized open label phase II clinical trial
Safety and efficacy of hydroxychloroquine for treatment of non-severe COVID-19 among adults in Uganda: a randomized open label phase II clinical trial Open
View article: Acute Respiratory Distress Syndrome in an African Intensive Care Unit Setting: A Prospective Study of Prevalence and Outcomes
Acute Respiratory Distress Syndrome in an African Intensive Care Unit Setting: A Prospective Study of Prevalence and Outcomes Open
"Acute Respiratory Distress Syndrome in an African Intensive Care Unit Setting: A Prospective Study of Prevalence and Outcomes." Annals of the American Thoracic Society, 19(4), pp. 691–694
View article: Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial
Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial Open
Introduction Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planne…
View article: Safety and Efficacy of Hydroxychloroquine for Treatment of Non-Severe COVID-19 in Adults in Uganda: A Randomized Open Label Phase II Clinical Trial
Safety and Efficacy of Hydroxychloroquine for Treatment of Non-Severe COVID-19 in Adults in Uganda: A Randomized Open Label Phase II Clinical Trial Open
Background Several repurposed drugs such as hydroxychloroquine (HCQ) have been investigated for treatment of COVID-19, but none was confirmed to be efficacious. While in vitro studies have demonstrated antiviral properties of HCQ, data fro…
View article: Epidemiology and Clinical Outcomes of Adults with Acute Respiratory Failure in a Low-Income Country: A Prospective, Observational, Multicentre Cohort Study
Epidemiology and Clinical Outcomes of Adults with Acute Respiratory Failure in a Low-Income Country: A Prospective, Observational, Multicentre Cohort Study Open
View article: Acute hypoxaemic respiratory failure in a low-income country: a prospective observational study of hospital prevalence and mortality
Acute hypoxaemic respiratory failure in a low-income country: a prospective observational study of hospital prevalence and mortality Open
Introduction Limited data exist on the epidemiology of acute hypoxaemic respiratory failure (AHRF) in low-income countries (LICs). We sought to determine the prevalence of AHRF in critically ill adult patients admitted to a Ugandan tertiar…
View article: Prevalence, patterns and factors associated with hypertensive crises in Mulago hospital emergency department; a cross-sectional study
Prevalence, patterns and factors associated with hypertensive crises in Mulago hospital emergency department; a cross-sectional study Open
Hypertensive emergencies are common and significantly associated with poor compliance to prescribed anti-hypertensive drugs. Acute stroke is the commonest presentation in our setting.
View article: Management of Severe Malaria and Severe Dengue in Resource-Limited Settings
Management of Severe Malaria and Severe Dengue in Resource-Limited Settings Open
View article: Infection Management in Patients with Sepsis and Septic Shock in Resource-Limited Settings
Infection Management in Patients with Sepsis and Septic Shock in Resource-Limited Settings Open
View article: Animal bite injuries in the accident and emergency unit at Mulago Hospital in Kampala, Uganda
Animal bite injuries in the accident and emergency unit at Mulago Hospital in Kampala, Uganda Open
Dog bites injuries from unrestrained, un-signaled dogs are the commonest source of animal bite injuries especially among children (<18 years). Vaccination against rabies was only confirmed for a very small number of dogs, as majority were …
View article: Current Challenges in the Management of Sepsis in ICUs in Resource-Poor Settings and Suggestions for the Future
Current Challenges in the Management of Sepsis in ICUs in Resource-Poor Settings and Suggestions for the Future Open