Jane Warwick
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Author Swipe
View article: Opportunistic offering of self-sampling to non-attenders within the English cervical screening programme: a pragmatic, multicentre, implementation feasibility trial with randomly allocated cluster intervention start dates (YouScreen)
Opportunistic offering of self-sampling to non-attenders within the English cervical screening programme: a pragmatic, multicentre, implementation feasibility trial with randomly allocated cluster intervention start dates (YouScreen) Open
North Central London and North East London Cancer Alliance.
View article: UK robotic arthroplasty clinical and cost effectiveness randomised controlled trial for hips (RACER-Hip): a study protocol
UK robotic arthroplasty clinical and cost effectiveness randomised controlled trial for hips (RACER-Hip): a study protocol Open
Introduction The number of robotic-assisted hip replacement procedures has expanded globally with the intended aim of improving outcomes. Intraoperative robotic-arm systems add additional costs to total hip replacement (THR) surgery but ma…
View article: Psychological Impact of the Galleri test (sIG(n)al): protocol for a longitudinal evaluation of the psychological impact of receiving a cancer signal in the NHS-Galleri trial
Psychological Impact of the Galleri test (sIG(n)al): protocol for a longitudinal evaluation of the psychological impact of receiving a cancer signal in the NHS-Galleri trial Open
Introduction Multi-cancer early detection (MCED) blood tests look for cancer signals in cell-free deoxyribonucleic acid. These tests have the potential to detect cancers at an earlier (asymptomatic) stage, improving cancer outcomes. Any sc…
View article: Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer
Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer Open
Objectives Whole-body magnetic resonance imaging (WB-MRI) has been demonstrated to be efficient and cost-effective for cancer staging. The study aim was to develop a machine learning (ML) algorithm to improve radiologists' sensitivity and …
View article: Psychological Impact of the Galleri Test (sIG(n)al): Protocol for a longitudinal evaluation of the psychological impact of receiving a cancer signal in the NHS-Galleri Trial
Psychological Impact of the Galleri Test (sIG(n)al): Protocol for a longitudinal evaluation of the psychological impact of receiving a cancer signal in the NHS-Galleri Trial Open
Introduction Multi-cancer early detection (MCED) blood tests look for cancer signals in cell-free deoxyribonucleic acid (cfDNA). These tests have the potential to detect cancers at an earlier (asymptomatic) stage, improving cancer outcomes…
View article: Opportunistic Offering of Self-Sampling to Non-Attenders within the English Cervical Screening Programme: A Pragmatic, Multicentre, Implementation Feasibility Trial with Randomly Allocated Cluster Intervention Start Dates (Youscreen)
Opportunistic Offering of Self-Sampling to Non-Attenders within the English Cervical Screening Programme: A Pragmatic, Multicentre, Implementation Feasibility Trial with Randomly Allocated Cluster Intervention Start Dates (Youscreen) Open
View article: Recommended summary plan for emergency care and treatment: ReSPECT a mixed-methods study
Recommended summary plan for emergency care and treatment: ReSPECT a mixed-methods study Open
Background Do not attempt cardiopulmonary resuscitation decisions have been widely criticised. The Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) process was developed to facilitate shared decisions between patients an…
View article: Correction: An online parenting intervention to prevent affective disorders in high-risk adolescents: the PIPA trial protocol
Correction: An online parenting intervention to prevent affective disorders in high-risk adolescents: the PIPA trial protocol Open
View article: Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis
Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis Open
Aims Observational studies indicate U-shaped associations of blood pressure (BP) and incident dementia in older age, but randomized controlled trials of BP-lowering treatment show mixed results on this outcome in hypertensive patients. A p…
View article: An online parenting intervention to prevent affective disorders in high-risk adolescents: the PIPA trial protocol
An online parenting intervention to prevent affective disorders in high-risk adolescents: the PIPA trial protocol Open
View article: Implementation of ReSPECT in acute hospitals: A retrospective observational study
Implementation of ReSPECT in acute hospitals: A retrospective observational study Open
View article: An online Parenting Intervention to Prevent affective disorders in high-risk Adolescents: The PIPA Trial Protocol
An online Parenting Intervention to Prevent affective disorders in high-risk Adolescents: The PIPA Trial Protocol Open
BackgroundAdolescent depression can place a young person at high risk of recurrence and a range of psychosocial and vocational impairments in adult life, highlighting the importance of early recognition and prevention. Parents/carers are w…
View article: The COV-ED Survey: exploring the impact of learning and teaching from home on parent/carers’ and teachers’ mental health and wellbeing during COVID-19 lockdown
The COV-ED Survey: exploring the impact of learning and teaching from home on parent/carers’ and teachers’ mental health and wellbeing during COVID-19 lockdown Open
View article: No clear associations between subjective memory concerns and subsequent change in cognitive function: the PATH through life study
No clear associations between subjective memory concerns and subsequent change in cognitive function: the PATH through life study Open
The literature on subjective memory concerns (SMC) as a predictor for future cognitive decline is varied. Furthermore, recent research has pointed to additional complexity arising from variability in the experience of SMC themselves (i.e. …
View article: Effect of managed transition on mental health outcomes for young people at the child–adult mental health service boundary: a randomised clinical trial
Effect of managed transition on mental health outcomes for young people at the child–adult mental health service boundary: a randomised clinical trial Open
Background Poor transition planning contributes to discontinuity of care at the child–adult mental health service boundary (SB), adversely affecting mental health outcomes in young people (YP). The aim of the study was to determine whether…
View article: Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy
Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy Open
isrctn.org Identifier: ISRCTN13254422.
View article: Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set
Effect of tourniquet use on the risk of revision in total knee replacement surgery: an analysis of the National Joint Registry Data Set Open
Objective Tourniquet use in total knee replacement (TKR) is believed to improve the bone-cement interface by reducing bleeding, potentially prolonging implant survival. This study aimed to compare the risk of revision for primary cemented …
View article: A video-feedback parenting intervention to prevent enduring behaviour problems in at-risk children aged 12–36 months: the Healthy Start, Happy Start RCT
A video-feedback parenting intervention to prevent enduring behaviour problems in at-risk children aged 12–36 months: the Healthy Start, Happy Start RCT Open
Background Behaviour problems emerge early in childhood and place children at risk for later psychopathology. Objectives To evaluate the clinical effectiveness and cost-effectiveness of a parenting intervention to prevent enduring behaviou…
View article: Infographic: Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery
Infographic: Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery Open
View article: A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children
A Brief Home-Based Parenting Intervention to Reduce Behavior Problems in Young Children Open
isrctn.org Identifier: ISRCTN58327365.
View article: Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery
Time to reconsider the routine use of tourniquets in total knee arthroplasty surgery Open
Aims Many surgeons choose to perform total knee arthroplasty (TKA) surgery with the aid of a tourniquet. A tourniquet is a device that fits around the leg and restricts blood flow to the limb. There is a need to understand whether tourniqu…
View article: Tourniquet use in total knee replacement surgery: a feasibility study and pilot randomised controlled trial (SAFE-TKR study)
Tourniquet use in total knee replacement surgery: a feasibility study and pilot randomised controlled trial (SAFE-TKR study) Open
Introduction Tourniquets are routinely used during total knee replacement (TKR) surgery. They could increase the risk of thromboembolic events including cerebral emboli, cognitive decline, pain and other adverse events (AEs). A randomised …
View article: Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration
Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration Open
ClinicalTrials.gov identifier: ISRCTN02335796.
View article: Validation of the Transition Readiness and Appropriateness Measure (TRAM) for the Managing the Link and Strengthening Transition from Child to Adult Mental Healthcare in Europe (MILESTONE) study
Validation of the Transition Readiness and Appropriateness Measure (TRAM) for the Managing the Link and Strengthening Transition from Child to Adult Mental Healthcare in Europe (MILESTONE) study Open
Objective Young people moving from child and adolescent mental health services (CAMHS) to adult mental health services (AMHS) are faced with significant challenges. To improve this state of affairs, there needs to be a recognition of the p…
View article: Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma
Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma Open
Recent advancement in the immunological understanding of genesis of hepatocellular carcinoma (HCC) has implicated a decline in anti-tumour immunity on the background of chronic inflammatory state of liver parenchyma. The development of HCC…
View article: Immunological Basis of Genesis of Hepatocellular Carcinoma: Unique Challenges and Potential Opportunities through Immunomodulation
Immunological Basis of Genesis of Hepatocellular Carcinoma: Unique Challenges and Potential Opportunities through Immunomodulation Open
A majority of hepatocellular carcinoma (HCC) develops in the setting of persistent chronic inflammation as immunological mechanisms have been shown to play a vital role in the initiation, growth and progression of tumours. The index review…
View article: Protocol for the development and validation procedure of the managing the link and strengthening transition from child to adult mental health care (MILESTONE) suite of measures
Protocol for the development and validation procedure of the managing the link and strengthening transition from child to adult mental health care (MILESTONE) suite of measures Open
View article: Methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients. Results from the MOTION trial
Methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients. Results from the MOTION trial Open
View article: Investigation of antihypertensive class, dementia, and cognitive decline
Investigation of antihypertensive class, dementia, and cognitive decline Open
Objective High blood pressure is one of the main modifiable risk factors for dementia. However, there is conflicting evidence regarding the best antihypertensive class for optimising cognition. Our objective was to determine whether any pa…
View article: Early versus deferred endovenous ablation of superficial venous reflux in patients with venous ulceration: the EVRA RCT
Early versus deferred endovenous ablation of superficial venous reflux in patients with venous ulceration: the EVRA RCT Open
Background Venous ulceration is a common and costly health-care issue worldwide, with poor healing rates greatly affecting patient quality of life. Compression bandaging has been shown to improve healing rates and reduce recurrence, but do…