Janet D. Conway
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View article: Local Antibiotic Delivery Systems and Their Applications in Orthopaedic Surgery
Local Antibiotic Delivery Systems and Their Applications in Orthopaedic Surgery Open
» Local antibiotic delivery systems are critical in managing periprosthetic and fracture-related infections, providing high local antibiotic concentrations without systemic side effects. Polymethyl methacrylate (PMMA), the first material t…
View article: Association Between Total Joint Arthroplasty and Surgical Complications in Patients With Valvular Heart Replacement: An Observational Study
Association Between Total Joint Arthroplasty and Surgical Complications in Patients With Valvular Heart Replacement: An Observational Study Open
View article: Stress fracture risk factors in soccer players: A systematic review
Stress fracture risk factors in soccer players: A systematic review Open
Background: This study conducted a systematic review to evaluate stress fracture risk factors in soccer players, aiming to enhance injury prevention strategies. Methods: We conducted a systematic review following Preferred Reporting Items …
View article: Outcomes and Complications of Arthroscopic Treatment for Septic Arthritis of the Hip: A Systematic Review.
Outcomes and Complications of Arthroscopic Treatment for Septic Arthritis of the Hip: A Systematic Review. Open
Utilizing arthroscopic techniques for treating septic arthritis of the hip represents a safe, effective, and minimally invasive choice, demonstrating favorable clinical results, relatively low rates of revision and complications, and rapid…
View article: Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review
Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review Open
Various imaging methods assist in diagnosing periprosthetic joint infection (PJI). These include radiological techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US); as well as advan…
View article: The Efficacy of Calcium Sulfate/Hydroxyapatite (CaS/HA) Gentamicin in Osteomyelitis Treatment: A Case Series
The Efficacy of Calcium Sulfate/Hydroxyapatite (CaS/HA) Gentamicin in Osteomyelitis Treatment: A Case Series Open
Background: Osteomyelitis is a challenging condition caused by infection and inflammation of the bone, presenting a significant economic burden to healthcare systems. Calcium sulfate/hydroxyapatite (CaS/HA) is a bone void filler composed o…
View article: Rethinking the Role of Formal Physical Therapy in Glenohumeral Osteoarthritis: A Nationwide Study Comprising More than Two Million Patients in the United States
Rethinking the Role of Formal Physical Therapy in Glenohumeral Osteoarthritis: A Nationwide Study Comprising More than Two Million Patients in the United States Open
Introduction: This study aims to determine whether incorporating physical therapy into a nonsurgical approach can effectively manage the course of glenohumeral osteoarthritis (OA) and potentially prevent patients from requiring total shoul…
View article: Poor Outcomes of Girdlestone Resection Arthroplasty in Injection Drug Users: A Retrospective Study
Poor Outcomes of Girdlestone Resection Arthroplasty in Injection Drug Users: A Retrospective Study Open
This retrospective cohort study aims to investigate the clinical outcomes of Girdlestone resection arthroplasty (GRA) in injection drug users with septic hip arthritis. Patients who underwent primary GRA for septic hip arthritis secondary …
View article: Phase 1 study of the pharmacokinetics and clinical proof-of-concept activity of a biofilm-disrupting human monoclonal antibody in patients with chronic prosthetic joint infection of the knee or hip
Phase 1 study of the pharmacokinetics and clinical proof-of-concept activity of a biofilm-disrupting human monoclonal antibody in patients with chronic prosthetic joint infection of the knee or hip Open
We report the results of a first-in-human phase 1 clinical study to evaluate TRL1068, a native human monoclonal antibody that disrupts bacterial biofilms with broad-spectrum activity against both Gram-positive and Gram-negative species. Th…
View article: Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis Open
View article: Local delivery of linezolid in the treatment of complex orthopedic bone and joint infections in patients with vancomycin allergy: a case series
Local delivery of linezolid in the treatment of complex orthopedic bone and joint infections in patients with vancomycin allergy: a case series Open
Introduction: Osteomyelitis is a challenging bone infection associated with ischemia, trauma, or various surgical procedures (e.g., joint reconstruction). Treatment involves eradicating infected bone and soft tissue, local antibiotic deliv…
View article: Limb Lengthening and Reconstruction Society orthopedic surgeons in the United States: An analysis of geographical distribution, academic, leadership, and demographic characteristics
Limb Lengthening and Reconstruction Society orthopedic surgeons in the United States: An analysis of geographical distribution, academic, leadership, and demographic characteristics Open
BACKGROUND The Limb Lengthening and Reconstruction Society (LLRS) is a premier orthopedic specialty organization that promotes limb reconstruction for all ages. LLRS membership characteristics, however, are poorly reported. This study deli…
View article: Antibiotic-Coated Intramedullary Nailing Managing Long Bone Infected Non-Unions: A Meta-Analysis of Comparative Studies
Antibiotic-Coated Intramedullary Nailing Managing Long Bone Infected Non-Unions: A Meta-Analysis of Comparative Studies Open
Long bone infected non-unions are such an orthopedic challenge that antibiotic-coated intramedullary nailing (ACIN) has become a viable therapeutic option for their management. This study aims to provide a comprehensive assessment of the a…
View article: Intravenous Drug Abuser Treated for Chronic Infected Open Forearm Fracture with Shortening and Primary Wound Closure
Intravenous Drug Abuser Treated for Chronic Infected Open Forearm Fracture with Shortening and Primary Wound Closure Open
Summary: Neglected and open forearm fracture wounds accompanied by shortening are complex injuries that are seldom reported in the known literature. We describe a patient with a history of chronic intravenous drug abuse (IVDA) and a neglec…
View article: Functional Outcomes of Knee Arthrodesis for Infected Total Knee Arthroplasty
Functional Outcomes of Knee Arthrodesis for Infected Total Knee Arthroplasty Open
Our results suggest that a knee arthrodesis is an acceptable option in patients with a persistent knee PJI with good functional PROMs and ambulatory status. Patients with shorter height, lower BMI, and younger age showed overall better out…
View article: Functional Outcome of Above-Knee Amputation After Infected Total Knee Arthroplasty
Functional Outcome of Above-Knee Amputation After Infected Total Knee Arthroplasty Open
View article: The Trans-Achilles Approach for Plate Supplementation of Ankle Arthrodesis With an Existing Hindfoot Fusion Nail: A Case Report
The Trans-Achilles Approach for Plate Supplementation of Ankle Arthrodesis With an Existing Hindfoot Fusion Nail: A Case Report Open
View article: Motorized Intramedullary Nail Lengthening in the Older Population
Motorized Intramedullary Nail Lengthening in the Older Population Open
Limb lengthening has not been widely employed in the elderly population due to concerns that outcomes will be inferior. The purpose of this multicenter, retrospective case-control series was to report the bone healing outcomes and complica…
View article: Fusion Revision Surgery With Reamer-Irrigator-Aspirator to Harvest Autograft After Spinal Pseudarthrosis
Fusion Revision Surgery With Reamer-Irrigator-Aspirator to Harvest Autograft After Spinal Pseudarthrosis Open
Background and purpose Spinal pseudarthrosis (SPA) is a common complication after attempted cervical or lumbosacral spinal fusion surgery. Revision surgeries usually necessitate bone graft implementation as an adjunct to hardware revision.…
View article: Intramedullary Canal Injection of Vancomycin- and Tobramycin-loaded Calcium Sulfate: A Novel Technique for the Treatment of Chronic Intramedullary Osteomyelitis
Intramedullary Canal Injection of Vancomycin- and Tobramycin-loaded Calcium Sulfate: A Novel Technique for the Treatment of Chronic Intramedullary Osteomyelitis Open
Elhessy AH, Rivera JC, Shu HT, et al. Intramedullary Canal Injection of Vancomycin- and Tobramycin-loaded Calcium Sulfate: A Novel Technique for the Treatment of Chronic Intramedullary Osteomyelitis. Strategies Trauma Limb Reconstr …
View article: Efficacy of Infection Eradication in Antibiotic Cement-Coated Intramedullary Nails for Fracture-Related Infections, Nonunions, and Fusions
Efficacy of Infection Eradication in Antibiotic Cement-Coated Intramedullary Nails for Fracture-Related Infections, Nonunions, and Fusions Open
Antibiotic cement-coated intramedullary nails (ACCINs) are increasing in popularity as a viable solution for the treatment of fracture-related infections (FRIs), infected long bone nonunions, and arthrodeses without an external fixator. AC…
View article: Tobramycin Blood Levels after Local Antibiotic Treatment of Bone and Soft Tissue Infection
Tobramycin Blood Levels after Local Antibiotic Treatment of Bone and Soft Tissue Infection Open
Local antibiotic delivery using different carriers plays an important role in both infection prophylaxis and treatment. Besides dead space management, these carriers have the advantage of providing a high concentration of local antibiotics…
View article: Outcomes of Total Knee Arthroplasty in Patients With a Prior Contralateral Above-Knee Amputation: A Retrospective Review of a Nationwide Database
Outcomes of Total Knee Arthroplasty in Patients With a Prior Contralateral Above-Knee Amputation: A Retrospective Review of a Nationwide Database Open
Our study revealed higher overall complications and longer LOS among TKAs in prior contralateral above-knee amputees. Surgeons should evaluate the risks and benefits of performing a TKA on patients with prior contralateral AKA.
View article: Immunological evaluation of patients with orthopedic infections: taking the Cierny–Mader classification to the next level
Immunological evaluation of patients with orthopedic infections: taking the Cierny–Mader classification to the next level Open
Introduction: Cierny–Mader osteomyelitis classification is used to label A, B, or C hosts based on comorbidities. This study's purpose was to define the “true” host status of patients with orthopedic infection using serologic markers to qu…
View article: Chronic Quadriceps Tendon Rupture Reconstruction with Sartorius Muscle Transfer: A Report of Five Cases
Chronic Quadriceps Tendon Rupture Reconstruction with Sartorius Muscle Transfer: A Report of Five Cases Open
Summary: Disruption of the knee extensor mechanism is an unfavorable situation because efficient mobilization requires a functioning knee extensor apparatus. The purpose of this retrospective study was to report our technique of sartorius …
View article: Orthopedic management of pubic symphysis osteomyelitis: a case series
Orthopedic management of pubic symphysis osteomyelitis: a case series Open
Objectives: The purpose of this case series is to describe the orthopedic management of pubic symphysis osteomyelitis with an emphasis on the key principles of treating bony infection. Furthermore, we sought to identify whether debridement…
View article: Treatment of Periprosthetic Joint Infection in Total Knee Arthroplasty with a Temporary Intramedullary Nail: Is a Long or Short Nail Better?
Treatment of Periprosthetic Joint Infection in Total Knee Arthroplasty with a Temporary Intramedullary Nail: Is a Long or Short Nail Better? Open
To our knowledge, no studies have compared postoperative outcomes between patients who received a temporary short or long intramedullary (IM) nail in the setting of infected total knee arthroplasty (TKA). Therefore, the aim of this study w…
View article: The induced membrane technique for bone defects: Basic science, clinical evidence, and technical tips
The induced membrane technique for bone defects: Basic science, clinical evidence, and technical tips Open
The clinical management of large bone defects continues to be a difficult clinical problem to manage for treating surgeons. The induced membrane technique is a commonly employed strategy to manage these complex injuries and achieve bone un…
View article: Experience with <scp>negative‐pressure</scp> wound therapy with instillation in complex infected orthopaedic wounds
Experience with <span>negative‐pressure</span> wound therapy with instillation in complex infected orthopaedic wounds Open
Chronic exudative wounds are frequently seen in hospitalised patients, consuming hospital resources and leading to increased morbidity. Negative‐pressure therapy (NPWT) with topical instillation “NPWTi” may be used to improve the wound hea…
View article: Risk Factors for Focal Osteolysis in a Stainless-Steel Limb-Lengthening Device
Risk Factors for Focal Osteolysis in a Stainless-Steel Limb-Lengthening Device Open
Background: Magnetic, telescoping intramedullary lengthening devices are widely used for treatment of limb length discrepancies. However, a routine radiographic review of a stainless-steel device demonstrated soft tissue and bony changes s…