Janet Sim
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View article: 1162 A nectin-4 targeted TLR9 agonist antibody conjugate induces robust immune cell activation and anti-tumor responses
1162 A nectin-4 targeted TLR9 agonist antibody conjugate induces robust immune cell activation and anti-tumor responses Open
Background Novel therapies that engage both innate and adaptive immune responses may engender durable anti-tumor immunity. Activation of Toll-Like Receptor 9 (TLR9) by unmethylated CpG oligonucleotides promotes innate inflammatory response…