Explanipedia

Drug resistant epilepsies: A multicentre case series of steroid therapy Open

Raffaele Falsaperla, Ausilia Desiree Collotta, Simona Domenica Marino, Vincenzo Sortino, Roberta Leonardi , et al. · 2024

Magnetic Resonance Imaging in Preterm Infant: A Systematic Review on Clinical Procedure Safety Open

Raffaele Falsaperla, Silvia Marino, Noemi Ganci, Guido Leone, Cátia Romano , et al. · 2024

Background: Currently, there is no evidence that MRI produces harmful effects on premature newborns, as well as short-term and long-term safety issues regarding radiofrequency fields and loud acoustic environment, while the examination tha…

Tracheostomy and long‐term invasive ventilation decision‐making in children: A scoping review Open

Cheryl Mack, Janette Mailo, Daniel Ofosu, Alreem Al Hinai, Diana Keto‐Lambert , et al. · 2024

An increasing number of children are surviving critical illnesses requiring tracheostomy/long‐term ventilation (LTV). This scoping review seeks to collate the available evidence on decision‐making for tracheostomy/LTV in children. Systemat…

C6 (Clinical Case) A 5-Year-Old with Headbanging and Hemiparesis Open

Jessica L. Foulds, Terra Morel, Janette Mailo · 2023

Introduction/Background A 5-year-old boy had a medical history of Phelan-McDermid syndrome; and with that associated autism spectrum disorder; severe, medication-resistant headbanging; and type 1 diabetes. He presented to community hospita…

Pediatric Moyamoya Revascularization Perioperative Care: A Modified Delphi Study Open

Lisa R. Sun, Lori C. Jordan, Edward R. Smith, Philipp R. Aldana, Matthew P. Kirschen , et al. · 2023

Perinatal Stroke: Clinical Pearls and Future Directions Open

Janette Mailo, Ratika Srivastava, Thilinie Rajapakse, Jerome Y. Yager · 2023

Perinatal strokes are disorders of cerebral vasculature occurring in the developing brain between 20 weeks of gestation and 28 days postnatally (Raju, 2007). This review describes specific types of perinatal strokes and includes up-to-date…

Pediatric Stroke and Cardiac Disease: Challenges in Recognition and Management Open

Elizabeth W. Mayne, Janette Mailo, Lisa Pabst, Elizabeth Pulcine, Dana Harrar , et al. · 2022

International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic Open

Lauren A. Beslow, Shannon C. Agner, Jonathan D. Santoro, Dipak Ram, Jenny L. Wilson , et al. · 2022

Background: Data from the early pandemic revealed that 0.62% of children hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had an acute arterial ischemic stroke (AIS). In a larger cohort from June 2020 to Decem…

Pediatric Encephalopathy and Complex Febrile Seizures Open

Amanda Yaworski, Rashid Alobaidi, Natarie Liu, Janette Mailo, Janani Kassiri · 2022

Startle Seizures and Diffuse Leukoencephalopathy After Resolution of Herpes Simplex Virus 1 Encephalitis in a Child Open

Andy Cheuk‐Him Ng, Janani Kassiri, Helly Goez, François D. Morneau-Jacob, Janette Mailo · 2022

We describe a unique clinical presentation of a child after the acute phase of herpes simplex virus 1 (HSV1) encephalitis. A 17-month-old boy first presented with HSV1 encephalitis and was promptly treated with antiviral medication. Seven …

P.117 Pediatric acute ischemic stroke protocols Open

Maria Gladkikh, Hugh J. McMillan, Andrea Andrade, Cyrus Boelman, I Bhatal , et al. · 2021

Background: Approximately 1,000 children present with AIS annually in North America. Most suffer from long-term disability. Childhood AIS is diagnosed after a median of 23 hours post-symptom onset, limiting thrombolytic treatment options t…

P.100 A Retrospective Study of Alberta Emergency Room Utilization by Pediatric Epilepsy Patients Open

Janani Kassiri, Janette Mailo, Thilinie Rajapakse, Wang Gt, Natarie Liu , et al. · 2021

Background: Epilepsy, a common neurologic condition, instigates a large number of emergency room (ER) visits annually. This project aims to retrospectively review the patterns and characteristics of Alberta ER visits by pediatric epilepsy …

Monogenic Syndromes with Congenital Heart Diseases in Newborns (Diagnostic Clues for Neonatologists): A Critical Analysis with Systematic Literature Review Open

Raffaele Falsaperla, Valentina Giacchi, Maria Giovanna Aguglia, Janette Mailo, Maria Grazia Longo , et al. · 2021

Congenital heart disease (CHD), the most common major congenital anomaly, is associated with a genetic syndrome (chromosomal anomalies, genomic disorders, or monogenic disease) in 30% of patients. The aim of this systematic review was to e…

Is Autonomic Nervous System Involved in the Epileptogenesis in Preterm Neonates? Open

Raffaele Falsaperla, Giovanna Vitaliti, Janette Mailo, Giovanni Corsello, Martino Ruggieri · 2021

Autonomic nervous system dysfunction has been described with focal and generalized epileptic seizures; occurring during their ictal, interictal, or postictal states. International League Against Epilepsy Seizure Classification Manual defin…

Steroid-therapy as therapeutic strategy for drug resistant epilepsies: A retrospective multicenter study Open

Raffaele Falsaperla, Simona Domenica Marino, Agnese Suppiej, Marilena Vecchi, Alberto Verrotti , et al. · 2021

The Objectives were twofold, first to evaluate the efficacy of steroids in refractory epilepsy in children, and second, to assess the effectiveness of the steroid treatment protocols used.We included 30 patients with medically refractory e…

Graph theory in paediatric epilepsy: A systematic review Open

Raffaele Falsaperla, Giovanna Vitaliti, Simona Domenica Marino, Andrea D. Praticò, Janette Mailo , et al. · 2021

Graph theoretical studies have been designed to investigate network topologies during life. Network science and graph theory methods may contribute to a better understanding of brain function, both normal and abnormal, throughout developme…

Ocular Motor Paroxysmal Events in Neonates and Infants: A Review of the Literature Open

Raffaele Falsaperla, Marco Andrea Nicola Saporito, Francesco Pisani, Janette Mailo, Piero Pavone , et al. · 2020

Early onset retinal dystrophies: clinical clues to diagnosis for pediatricians Open

Agnese Suppiej, Silvia Marino, Maria Eleonora Reffo, V. Maritan, Giovanna Vitaliti , et al. · 2019

Developmental EEG hallmark or biological artifact? Glossokinetic artifact mimicking anterior slow dysrhythmia in two full term newborns Open

Raffaele Falsaperla, Simona Domenica Marino, Maria Giovanna Aguglia, Giulia Cupitò, Francesco Pisani , et al. · 2019

The aim of this paper is to describe an uncommon physiological EEG artifact in newborns caused by tongue movements (TM), mimicking anterior slow dysrhythmia (ASD). The subjects are two full-term newborns (39 weeks gestational age (GA)), ad…

P.073 Improving access to urgent neurology care for pediatric patients Open

Amanda Yaworski, Jerome Y. Yager, Janette Mailo, Lawrence Richer, Thilinie Rajapakse , et al. · 2019

Background: Pediatric neurology referral wait times are increasing, often leading to emergency department (ED) utilization. On average 5% of ED patients present with neurological symptoms and 35% of ED neurological diagnoses are revised af…

Breaking the cycle: A comparison between intravenous immunoglobulins and high dosage prednisone in the treatment of medically intractable epilepsy in children Open

Richard Tang‐Wai, Janette Mailo, Bernard Rosenblatt · 2017

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