Janne Martikainen
YOU?
Author Swipe
View article: Sickness absences and losses in productivity-adjusted life years before, during and after the most common orthopedic surgical procedures among employed individuals in Finland
Sickness absences and losses in productivity-adjusted life years before, during and after the most common orthopedic surgical procedures among employed individuals in Finland Open
Background Musculoskeletal diseases requiring surgical procedures in working-age adults impose a significant financial burden on many societies. This observational study focused on evaluating the seven most common elective orthopedic surge…
View article: Metabolites associated with abnormal glucose metabolism responding to primary care lifestyle intervention
Metabolites associated with abnormal glucose metabolism responding to primary care lifestyle intervention Open
View article: Losses in productivity-adjusted life years before, during and after orthopedic surgeries in Finland
Losses in productivity-adjusted life years before, during and after orthopedic surgeries in Finland Open
Background Musculoskeletal diseases requiring surgical procedures in working-age adults impose a significant financial burden on many societies. We evaluated seven most common elective orthopedic surgeries among the Finnish working-age emp…
View article: Scoping Review of Productivity-Adjusted Life Years (PALYs): Methods, Applications and Policy Implications
Scoping Review of Productivity-Adjusted Life Years (PALYs): Methods, Applications and Policy Implications Open
PALYs have been utilised in diverse diseases and contexts, highlighting their utility in measuring societal health impacts. However, adding unpaid and informal work makes burden estimates more accurate. The increasing emphasis on preventio…
View article: Health Care Workload Impacts and Cost-Effectiveness of a Metabolomic Risk Score-based Health Check for Cardiometabolic Disease Prevention in Finland
Health Care Workload Impacts and Cost-Effectiveness of a Metabolomic Risk Score-based Health Check for Cardiometabolic Disease Prevention in Finland Open
Background We evaluated the impact on health care professionals’ workload and the long-term cost-effectiveness of a novel metabolomic risk score (MRS)-based health check compared with current practices in Finland’s working-age population. …
View article: Microsimulation Modeling for Health Decision Sciences Using C++: A Tutorial
Microsimulation Modeling for Health Decision Sciences Using C++: A Tutorial Open
Microsimulation models have become increasingly common in the field of decision modeling for health. Because microsimulation models are computationally more demanding than traditional Markov cohort models, the use of computer programming l…
View article: Long‐term health economic evaluation of automated insulin delivery system compared with continuous subcutaneous insulin infusion pumps and <scp>CGM</scp> in a real‐world setting in Finnish paediatric and adult individuals with type 1 diabetes
Long‐term health economic evaluation of automated insulin delivery system compared with continuous subcutaneous insulin infusion pumps and <span>CGM</span> in a real‐world setting in Finnish paediatric and adult individuals with type 1 diabetes Open
Aims The use of automated insulin delivery (AID) systems is associated with improved glycaemic control in individuals with type 1 diabetes (T1DM). However, AID systems are more expensive than other treatment modalities for T1DM. The aim of…
View article: Explainable Prediction of Long-Term Glycated Hemoglobin Response Change in Finnish Patients with Type 2 Diabetes Following Drug Initiation Using Evidence-Based Machine Learning Approaches
Explainable Prediction of Long-Term Glycated Hemoglobin Response Change in Finnish Patients with Type 2 Diabetes Following Drug Initiation Using Evidence-Based Machine Learning Approaches Open
Using EHR and ML models allows for the development of more realistic and individualized predictions of HbA1c changes, accounting for more diverse patient populations and their heterogeneous nature, offering more tailored and effective trea…
View article: The Impact of Chronic Conditions on Productivity-Adjusted Life-Years in Both the Workplace and Household Settings in the General Adult Population in Finland
The Impact of Chronic Conditions on Productivity-Adjusted Life-Years in Both the Workplace and Household Settings in the General Adult Population in Finland Open
Depression and other mental health problems have a major effect on self-reported work ability and productivity compared with other chronic conditions.
View article: Risk-stratified analysis of long-term clinical outcomes and cumulative costs in Finnish patients with recent acute coronary syndrome or coronary revascularization: a 5-year real-world study using electronic health records
Risk-stratified analysis of long-term clinical outcomes and cumulative costs in Finnish patients with recent acute coronary syndrome or coronary revascularization: a 5-year real-world study using electronic health records Open
Aims Risk assessment is essential in the prevention of cardiovascular disease. In patients with recent acute coronary syndrome (ACS) or coronary revascularization, risk prediction tools, like the European Society of Cardiology guideline re…
View article: Effectiveness of the Coordinated Return to Work model after orthopaedic surgery for lumbar discectomy and hip and knee arthroplasty: a register-based study
Effectiveness of the Coordinated Return to Work model after orthopaedic surgery for lumbar discectomy and hip and knee arthroplasty: a register-based study Open
Objectives This study examined the effectiveness of an individualised Coordinated Return to Work (CRtW) model on the length of the return to work (RTW) period compared with a standard prescription of 2–3 months RTW during recovery after lu…
View article: Agreement between physician- and patient-reported Canadian cardiovascular society scores among patients undergoing elective coronary angiography–The CATS study
Agreement between physician- and patient-reported Canadian cardiovascular society scores among patients undergoing elective coronary angiography–The CATS study Open
The primary aim of revascularization in stable coronary artery disease (CAD) is symptom relief. The severity of symptoms is usually evaluated by the physician, not by the patient. We examined the agreement between physician- and patient-re…
View article: Suomalaisväestön maksuhalukkuus terveyteen liittyvästä elämänlaadusta
Suomalaisväestön maksuhalukkuus terveyteen liittyvästä elämänlaadusta Open
Kustannusvaikuttavuusanalyysit tuottavat tietoa interventioiden kustannusvaikuttavuudesta, mitä hyödynnetään päätettäessä resurssien allokoinnista terveydenhuollossa. Koska terveydenhuollon päätöksenteko vaikuttaa koko väestöön sekä veronm…
View article: Data-Driven Identification of Long-Term Glycemia Clusters and Their Individualized Predictors in Finnish Patients with Type 2 Diabetes
Data-Driven Identification of Long-Term Glycemia Clusters and Their Individualized Predictors in Finnish Patients with Type 2 Diabetes Open
Heterogeneity in long-term glycemic control can be predicted with confidence by utilizing information from previous HbA1c levels, fasting plasma glucose, duration of T2D, and use of antidiabetic medications. In future, the expected develop…
View article: RWD31 Secure Processing Environments (SPE) Are Needed for the Cybersecure Collection and Secondary Use of Personal, Health, and Social Data
RWD31 Secure Processing Environments (SPE) Are Needed for the Cybersecure Collection and Secondary Use of Personal, Health, and Social Data Open
View article: Economic evaluation of infliximab, synthetic triple therapy and methotrexate in the treatment of newly diagnosed juvenile idiopathic arthritis
Economic evaluation of infliximab, synthetic triple therapy and methotrexate in the treatment of newly diagnosed juvenile idiopathic arthritis Open
View article: Effects of COVID-19 Pandemic and Lockdown on Monitoring and Treatment Balance of Finnish Coronary Heart Disease and Type 2 Diabetes Patients
Effects of COVID-19 Pandemic and Lockdown on Monitoring and Treatment Balance of Finnish Coronary Heart Disease and Type 2 Diabetes Patients Open
The lockdown decreased the frequency of monitoring among both CHD and T2D patients. Meanwhile, monthly average LDL had a steadily improving pattern in CHD patients during the follow-up while temporary worsening in HbA1c in patients with T2…
View article: Real-world effectiveness of digital and group-based lifestyle interventions as compared with usual care to reduce type 2 diabetes risk – A stop diabetes pragmatic randomised trial
Real-world effectiveness of digital and group-based lifestyle interventions as compared with usual care to reduce type 2 diabetes risk – A stop diabetes pragmatic randomised trial Open
Strategic Research Council at Academy of Finland, Academy of Finland, Novo Nordisk Foundation, and Finnish Diabetes Research foundation.
View article: Modelling health and economic impact of nutrition interventions: a systematic review
Modelling health and economic impact of nutrition interventions: a systematic review Open
View article: Economic evaluation of using polygenic risk score to guide risk screening and interventions for the prevention of type 2 diabetes in individuals with high overall baseline risk
Economic evaluation of using polygenic risk score to guide risk screening and interventions for the prevention of type 2 diabetes in individuals with high overall baseline risk Open
Type 2 diabetes (T2D) with increasing prevalence is a significant global public health challenge. Obesity, unhealthy diet, and low physical activity are one of the major determinants of the rise in T2D prevalence. In addition, family histo…
View article: Willingness to Pay for Implementation of an Environmentally Friendly Pharmaceutical Policy in Finland—A Discrete Choice Experiment Study
Willingness to Pay for Implementation of an Environmentally Friendly Pharmaceutical Policy in Finland—A Discrete Choice Experiment Study Open
The use of pharmaceuticals is their main pathway to the environment, making the public a major stakeholder in environmentally friendly pharmaceutical policies, including an environmental classification system for medicines. We studied the …
View article: Hospital treatment costs associated with incident complications in patients with type 2 diabetes—real-world study based on electronic patient information systems
Hospital treatment costs associated with incident complications in patients with type 2 diabetes—real-world study based on electronic patient information systems Open
View article: Marked Improvement in A1C Levels After Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Maintained Over 4 Years in Patients With Type 1 Diabetes
Marked Improvement in A1C Levels After Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Maintained Over 4 Years in Patients With Type 1 Diabetes Open
Objective This study aimed to demonstrate the effectiveness of long-term use of intermittently scanned continuous glucose monitoring (isCGM) in adult patients with type 1 diabetes. Design and methods In this retrospective real-world study,…
View article: Digitally Supported Lifestyle Intervention to Prevent Type 2 Diabetes Through Healthy Habits: Secondary Analysis of Long-Term User Engagement Trajectories in a Randomized Controlled Trial
Digitally Supported Lifestyle Intervention to Prevent Type 2 Diabetes Through Healthy Habits: Secondary Analysis of Long-Term User Engagement Trajectories in a Randomized Controlled Trial Open
Background Digital health interventions may offer a scalable way to prevent type 2 diabetes (T2D) with minimal burden on health care systems by providing early support for healthy behaviors among adults at increased risk for T2D. However, …
View article: Digitalization as an Engine for Change? Building a Vision Pathway towards a Sustainable Health Care System by Using the MLP and Health Economic Decision Modelling
Digitalization as an Engine for Change? Building a Vision Pathway towards a Sustainable Health Care System by Using the MLP and Health Economic Decision Modelling Open
Grand social challenges, such as type 2 diabetes (T2D), are increasing, which creates sustainability problems for health care service systems. To reduce socio-economic burdens, changes are required in the socio-technical system. However, t…
View article: Type 2 Diabetes-Related Health Economic Impact Associated with Increased Whole Grains Consumption among Adults in Finland
Type 2 Diabetes-Related Health Economic Impact Associated with Increased Whole Grains Consumption among Adults in Finland Open
The prevalence of type 2 diabetes (T2D) is increasing rapidly worldwide. A healthy diet supporting the control of energy intake and body weight has major importance in the prevention of T2D. For example, a high intake of whole grain foods …
View article: Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study
Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study Open
Background Clinical trials have shown that type 2 diabetes (T2D) is preventable through lifestyle interventions targeting high-risk people. Nevertheless, large-scale implementation of risk identification followed by preventive intervention…
View article: Pharmacy-based screening to detect persons at elevated risk of type 2 diabetes: a cost-utility analysis
Pharmacy-based screening to detect persons at elevated risk of type 2 diabetes: a cost-utility analysis Open
Background Early identification of people at elevated risk of type 2 diabetes (T2D) is an important step in preventing or delaying its onset. Pharmacies can serve as a significant channel to reach these people. This study aimed to assess t…
View article: Patient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D
Patient-reported outcomes in coronary artery disease: the relationship between the standard, disease-specific set by the International Consortium for Health Outcomes Measurement (ICHOM) and the generic health-related quality of life instrument 15D Open
View article: Pharmacy-based screening to detect persons at elevated risk of type 2 diabetes: a cost-utility analysis
Pharmacy-based screening to detect persons at elevated risk of type 2 diabetes: a cost-utility analysis Open
Background Early identification of people at elevated risk of type 2 diabetes (T2D) is an important step in preventing or delaying its onset. Pharmacies can serve as a significant channel to reach these people. This study aimed to assess t…