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View article: Scalable and cost-effective methods for xenomonitoring of P. falciparum and antimalarial drug resistance validated with laboratory and wild-caught mosquitoes
Scalable and cost-effective methods for xenomonitoring of P. falciparum and antimalarial drug resistance validated with laboratory and wild-caught mosquitoes Open
Human blood samples serve as the gold standard for molecular surveillance of the malaria parasite Plasmodium falciparum . However, these samples may not accurately reflect the parasite population and come with logistical constraints and et…
View article: Optimising the use of Oxford nanopore sequencing technology for detection of<i>Wolbachia</i>bacterial endosymbionts in<i>Anopheles</i>mosquitoes
Optimising the use of Oxford nanopore sequencing technology for detection of<i>Wolbachia</i>bacterial endosymbionts in<i>Anopheles</i>mosquitoes Open
Malaria, a mosquito-borne disease predominantly affecting sub-Saharan Africa, remains a significant global health challenge with 263 million cases in 2023. Although progress in vaccine development has recently occurred, insecticide resista…
View article: A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations
A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations Open
Robust diagnostic tools and surveillance are crucial for malaria control and elimination efforts. Malaria caused by neglected Plasmodium parasites is often underestimated due to the lack of rapid diagnostic tools that can accurately detect…
View article: Detection of insecticide resistance markers in Anopheles funestus from the Democratic Republic of the Congo using a targeted amplicon sequencing panel
Detection of insecticide resistance markers in Anopheles funestus from the Democratic Republic of the Congo using a targeted amplicon sequencing panel Open
View article: Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo
Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo Open
View article: Investigating Molecular Mechanisms of Insecticide Resistance in the Eastern Democratic Republic of the Congo
Investigating Molecular Mechanisms of Insecticide Resistance in the Eastern Democratic Republic of the Congo Open
Background Malaria vector control in the Democratic Republic of the Congo is plagued by several major challenges, including inadequate infrastructure, lack of access to health care systems and preventative measures, and more recently the w…
View article: Stable high-density and maternally inherited Wolbachia infections in Anopheles moucheti and Anopheles demeilloni mosquitoes
Stable high-density and maternally inherited Wolbachia infections in Anopheles moucheti and Anopheles demeilloni mosquitoes Open
Wolbachia, a widespread bacterium that can reduce pathogen transmission in mosquitoes, has recently been reported to be present in Anopheles (An.) species. In wild populations of the An. gambiae complex, the primary vectors of Plasmodium m…
View article: Additional file 1 of Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo
Additional file 1 of Investigating molecular mechanisms of insecticide resistance in the Eastern Democratic Republic of the Congo Open
Additional file 1: TableS1. Summary of all published insecticide resistance mechanism data from the DRC.
View article: Identification of main malaria vectors and their insecticide resistance profile in internally displaced and indigenous communities in Eastern Democratic Republic of the Congo (DRC)
Identification of main malaria vectors and their insecticide resistance profile in internally displaced and indigenous communities in Eastern Democratic Republic of the Congo (DRC) Open
View article: Genomic and microscopic evidence of stable high density and maternally inherited<i>Wolbachia</i>infections in<i>Anopheles</i>mosquitoes
Genomic and microscopic evidence of stable high density and maternally inherited<i>Wolbachia</i>infections in<i>Anopheles</i>mosquitoes Open
Wolbachia , a widespread bacterium that can reduce pathogen transmission in mosquitoes, has been detected within populations of Anopheles (An.) malaria vectors. In the An. gambiae complex, the primary vectors in Sub-Saharan Africa, Wolbach…
View article: Additional file 1 of Identification of main malaria vectors and their insecticide resistance profile in internally displaced and indigenous communities in Eastern Democratic Republic of the Congo (DRC)
Additional file 1 of Identification of main malaria vectors and their insecticide resistance profile in internally displaced and indigenous communities in Eastern Democratic Republic of the Congo (DRC) Open
Additional file 1: Excel sheet with details of kdr genotypes from mosquito samples collected via CDC light traps and Excel sheet with details on kdr genotypes from mosquitoes exposed to different insecticides in the WHO insecticide suscept…
View article: Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa
Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa Open
Background: Wolbachia, a common insect endosymbiotic bacterium that can influence pathogen transmission and manipulate host reproduction, has historically been considered absent from the Anopheles (An.) genera, but has recently been found …
View article: Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa
Novel Wolbachia strains in Anopheles malaria vectors from Sub-Saharan Africa Open
Background: Wolbachia , a common insect endosymbiotic bacterium that can influence pathogen transmission and manipulate host reproduction, has historically been considered absent from the Anopheles (An.) genera, but has recently been foun…
View article: Identification of Anopheles species in Sud Kivu, Democratic Republic of Congo, using molecular tools
Identification of Anopheles species in Sud Kivu, Democratic Republic of Congo, using molecular tools Open
The mosquito fauna of the Democratic Republic of Congo remains understudied, including that of the province of Sud Kivu. To improve understanding of species presenting Sud Kivu, adult mosquitoes were collected from houses and larvae were c…
View article: Novel <i>Wolbachia</i> strains in <i>Anopheles</i> malaria vectors from Sub-Saharan Africa
Novel <i>Wolbachia</i> strains in <i>Anopheles</i> malaria vectors from Sub-Saharan Africa Open
Anopheles (An.) mosquitoes contain bacteria that can influence Plasmodium parasites. Wolbachia , a common insect endosymbiont, has historically been considered absent from Anopheles but has recently been found in An. gambiae populations. H…
View article: Malaria vector studies to determine MSF’s strategy for malaria vector control in the Democratic Republic of Congo (DRC)
Malaria vector studies to determine MSF’s strategy for malaria vector control in the Democratic Republic of Congo (DRC) Open