Jaqueline Carvalho de Oliveira
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View article: Impact of long COVID phenotypes on quality of life following symptomatic omicron infection in Brazil: a machine learning analysis
Impact of long COVID phenotypes on quality of life following symptomatic omicron infection in Brazil: a machine learning analysis Open
View article: TERAPIAS ADJUVANTES NO CÂNCER DE MAMA: EVIDÊNCIAS CLÍNICAS COM Β-GLUCANO DE PLEURAN E POLISSACARÍDEOS DE ASTRAGALUS
TERAPIAS ADJUVANTES NO CÂNCER DE MAMA: EVIDÊNCIAS CLÍNICAS COM Β-GLUCANO DE PLEURAN E POLISSACARÍDEOS DE ASTRAGALUS Open
View article: Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID‐19
Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID‐19 Open
The coronavirus disease 2019 (COVID‐19) pandemic has triggered a global health crisis, with over 700 million confirmed cases and at least 7 million deaths reported by early 2024. Children are less vulnerable to severe SARS‐CoV‐2 infection …
View article: Real-world accuracy of SARS-CoV-2 antigen detection compared with qPCR: A cross-sectional study in Toledo - PR, Brazil
Real-world accuracy of SARS-CoV-2 antigen detection compared with qPCR: A cross-sectional study in Toledo - PR, Brazil Open
Rapid Antigen Tests (Ag-RDTs) for the detection of SARS-CoV-2 is an important diagnostic tool for containing virus spread. However, their accuracy ‒ the proportion of correct results (both true positives and true negatives) ‒ still needs t…
View article: Multisystem Inflammatory Syndrome and Severe COVID-19 in children have distinct metabolism pathways affected by pathogenic genetic variants.
Multisystem Inflammatory Syndrome and Severe COVID-19 in children have distinct metabolism pathways affected by pathogenic genetic variants. Open
The coronavirus disease 2019 (COVID-19) pandemic has triggered a global health crisis, with over 700 million confirmed cases and at least 7 million deaths reported by early 2024. Children are less vulnerable to severe SARS-CoV-2 infection …
View article: The Functional Map of Ultraconserved Regions in Humans, Mice and Rats
The Functional Map of Ultraconserved Regions in Humans, Mice and Rats Open
BACKGROUND: Ultraconserved regions (UCRs) encompass 481 DNA segments exceeding 200 base pairs (bp), displaying 100% sequence identity across humans, mice, and rats, indicating profound conservation across taxa and pivotal functional roles …
View article: A Retrospective Cross-Sectional Analysis of Viral SARI in Pregnant Women in Southern Brazil
A Retrospective Cross-Sectional Analysis of Viral SARI in Pregnant Women in Southern Brazil Open
Pregnant women (PW) are at a higher risk of diseases and hospitalization from viral respiratory infections, particularly influenza and SARS-CoV-2, due to cardiopulmonary and immunological changes. This study assessed the impact of viral re…
View article: “A Retrospective Cross-Sectional Analysis of Viral Sari in Pregnant Women in Southern Brazil”
“A Retrospective Cross-Sectional Analysis of Viral Sari in Pregnant Women in Southern Brazil” Open
Pregnant women (PW) are at a higher risk of diseases and hospitalization from viral respiratory infections, specially influenza, due to cardiopulmonary and immunological changes. This study assessed the impact of viral respiratory infectio…
View article: Influenza A, like Omicron SARS-CoV-2, Is Similarly Detected in Saliva or Nasopharyngeal Samples via RT-qPCR
Influenza A, like Omicron SARS-CoV-2, Is Similarly Detected in Saliva or Nasopharyngeal Samples via RT-qPCR Open
After the Coronavirus pandemic, the importance of virus surveillance was highlighted, reinforcing the constant necessity of discussing and updating the methods for collection and diagnoses, including for other respiratory viruses. Although…
View article: PD-1/PD-L1 Inhibitors Response in Triple-Negative Breast Cancer: Can Long Noncoding RNAs Be Associated?
PD-1/PD-L1 Inhibitors Response in Triple-Negative Breast Cancer: Can Long Noncoding RNAs Be Associated? Open
As immune checkpoint inhibitors (ICI) emerge as a paradigm-shifting treatment option for patients with advanced or metastatic cancer, there is a growing demand for biomarkers that can distinguish which patients are likely to benefit. In th…
View article: BNT162b2 mRNA COVID-19 against symptomatic Omicron infection following a mass vaccination campaign in southern Brazil: A prospective test-negative design study
BNT162b2 mRNA COVID-19 against symptomatic Omicron infection following a mass vaccination campaign in southern Brazil: A prospective test-negative design study Open
ClinicalTrials.gov number, NCT05052307 (https://clinicaltrials.gov/ct2/show/NCT05052307).
View article: Molecular BCR::ABL1 Quantification and ABL1 Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study
Molecular BCR::ABL1 Quantification and ABL1 Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study Open
Chronic myeloid leukemia (CML) is a well-characterized oncological disease in which virtually all patients possess a translocation (9;22) that generates the tyrosine kinase BCR::ABL1 protein. This translocation represents one of the milest…
View article: COVID-19 impedimetric biosensor based on polypyrrole nanotubes, nickel hydroxide and VHH antibody fragment: specific, sensitive, and rapid viral detection in saliva samples
COVID-19 impedimetric biosensor based on polypyrrole nanotubes, nickel hydroxide and VHH antibody fragment: specific, sensitive, and rapid viral detection in saliva samples Open
View article: LncRNA-SNPs in a Brazilian Breast Cancer Cohort: A Case-Control Study
LncRNA-SNPs in a Brazilian Breast Cancer Cohort: A Case-Control Study Open
Long noncoding RNAs (lncRNAs) are a class of non-coding RNAs that contain more than 200 nucleotides and exhibit a versatile regulatory capacity. Genomic alterations in lncRNAs have already been investigated in several complex diseases, inc…
View article: VIABILIDADE POLÍNICA DE ESCHWEILERA (DC.) S.A MORI NO PERÍMETRO URBANO DE ALTA FLORESTA – MT
VIABILIDADE POLÍNICA DE ESCHWEILERA (DC.) S.A MORI NO PERÍMETRO URBANO DE ALTA FLORESTA – MT Open
O presente trabalho objetivou avaliar a viabilidade polínica de dois indivíduos de Eschweilera coriaceae por meio de testes colorimétricos. O experimento foi realizado no Laboratório de Citogenética e Cultura de Tecidos Vegetais, na Univer…
View article: Lnc-uc.147 Is Associated with Disease Stage of Liver, Gastric, and Renal Cancer
Lnc-uc.147 Is Associated with Disease Stage of Liver, Gastric, and Renal Cancer Open
Lnc-uc.147, a long non-coding RNA derived from a transcribed ultraconserved region (T-UCR), was previously evidenced in breast cancer. However, the role of this region in other tumor types was not previously investigated. The present study…
View article: Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers
Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers Open
The ultraconserved regions (UCRs) are 481 genomic elements, longer than 200 bp, 100% conserved in human, mouse, and rat genomes. Usually, coding regions are more conserved, but more than 80% of UCRs are either intergenic or intronic, and m…
View article: Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers
Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers Open
The ultraconserved regions (UCRs) are 481 genomic elements, longer than 200 bp, 100% conserved in human, mouse, and rat genomes. Usually, coding regions are more conserved, but more than 80% of UCRs are either intergenic or intronic, and m…
View article: Evaluation of Influenza A and SARS-CoV2 detection using RT-PCR by paired saliva and nasopharyngeal secretions samples
Evaluation of Influenza A and SARS-CoV2 detection using RT-PCR by paired saliva and nasopharyngeal secretions samples Open
Introduction:The Human Influenza Virus (IFV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) are both etiologic agents for acute upper respiratory diseases and can be lethal.Both can evolve and spread rapidly, being an outb…
View article: ldentification of genomic variants of the SARS-CoV-2 Virus in patients admitted to a reference hospital in Curitiba/PR and the relationship with the clinical condition
ldentification of genomic variants of the SARS-CoV-2 Virus in patients admitted to a reference hospital in Curitiba/PR and the relationship with the clinical condition Open
Introduction: The coronavirus disease (COVID-19) has a variable clinical picture, ranging from patients with mild and nonspecific symptoms to severe symptoms such as respiratory distress syndrome and death. Objectives: To identify the gene…
View article: Genetic features related to the severity of SARS-CoV-2 infection in pediatric patients: analysis of whole exome sequencing data
Genetic features related to the severity of SARS-CoV-2 infection in pediatric patients: analysis of whole exome sequencing data Open
With the emergence of the COVID-19 pandemic, the world has entered into a global health emergency. The increased spread of SARS-CoV-2 has led to reports of severe illness in pediatric patients, simila
View article: Identificação de variantes genômicas do vírus SARS-CoV-2 em pacientes internados em um hospital de referência de Curitiba/PR e a relação com o quadro clínico
Identificação de variantes genômicas do vírus SARS-CoV-2 em pacientes internados em um hospital de referência de Curitiba/PR e a relação com o quadro clínico Open
View article: The Double Face of miR-708: A Pan-Cancer Player with Dissociative Identity Disorder
The Double Face of miR-708: A Pan-Cancer Player with Dissociative Identity Disorder Open
Over the last decades, accumulating evidence has shown tumor-dependent profiles of miR-708, being either up- or downregulated, and thus, acting as a “Janus” regulator of oncogenic pathways. Herein, its functional duality was assessed throu…
View article: The Potential of NORAD–PUMILIO–RALGAPB Regulatory Axis as a Biomarker in Breast Cancer
The Potential of NORAD–PUMILIO–RALGAPB Regulatory Axis as a Biomarker in Breast Cancer Open
Introduction: Long non-coding RNAs (LncRNA) represent a heterogeneous family of RNAs that have emerged as regulators of various biological processes through their association with proteins in ribonucleoproteins complexes. The dynamic of th…
View article: BNT162b2 against COVID-19 in Brazil using a test-negative design: Study protocol and statistical analysis plan
BNT162b2 against COVID-19 in Brazil using a test-negative design: Study protocol and statistical analysis plan Open
Introduction Real-world data on COVID-19 vaccine effectiveness are needed to validate evidence from randomized clinical trials. Accordingly, this study aims to evaluate, in a real-world setting in Brazil, the effectiveness of Pfizer-BioNTe…
View article: Plataforma de monitoramento das empresas para a sustentabilidade
Plataforma de monitoramento das empresas para a sustentabilidade Open
O Observatório 2030 foi criado pela Rede Brasil do Pacto Global para acompanhar e cobrar das empresas alinhamento com os Objetivos de Desenvolvimento Sustentável – e já mostra a necessidade de aumentar o ritmo da mudança.
View article: MicroRNAs miR-142-5p, miR-150-5p, miR-320a-3p, and miR-4433b-5p in Serum and Tissue: Potential Biomarkers in Sporadic Breast Cancer
MicroRNAs miR-142-5p, miR-150-5p, miR-320a-3p, and miR-4433b-5p in Serum and Tissue: Potential Biomarkers in Sporadic Breast Cancer Open
Breast cancer (BC) is a heterogeneous disease, and establishing biomarkers is essential to patient management. We previously described that extracellular vesicle–derived miRNAs (EV-miRNAs) miR-142-5p, miR-150-5p, miR-320a, and miR-4433b-5p…
View article: SARS-CoV-2 Delta and Omicron Variants Surge in Curitiba, Southern Brazil, and Its Impact on Overall COVID-19 Lethality
SARS-CoV-2 Delta and Omicron Variants Surge in Curitiba, Southern Brazil, and Its Impact on Overall COVID-19 Lethality Open
Screening efforts and genomic surveillance are essential tools to evaluate the course of the COVID-19 pandemic and assist the public healthcare system in dealing with an increasing number of infections. For the analysis of COVID-19 cases s…
View article: A FORMAÇÃO ARTÍSTICO-CULTURAL DOS PROFESSORES DE EDUCAÇÃO FÍSICA E O CONTEÚDO DANÇA NA ESCOLA
A FORMAÇÃO ARTÍSTICO-CULTURAL DOS PROFESSORES DE EDUCAÇÃO FÍSICA E O CONTEÚDO DANÇA NA ESCOLA Open
O presente artigo tem como objetivo analisar de que modo a formação artístico-cultural dos professores de Educação Física interfere no trato do conteúdo dança na escola. A metodologia utilizada foi uma pesquisa de campo, através de questio…
View article: Comparison of SARS-CoV-2 molecular detection in nasopharyngeal swab, saliva, and gargle samples
Comparison of SARS-CoV-2 molecular detection in nasopharyngeal swab, saliva, and gargle samples Open