Jarl E. S. Wikberg
YOU?
Author Swipe
View article: Melanocortin receptors in GtoPdb v.2025.3
Melanocortin receptors in GtoPdb v.2025.3 Open
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogeno…
Melanocortin receptors in GtoPdb v.2023.1 Open
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogeno…
Melanocortin receptors in GtoPdb v.2021.3 Open
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [41]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogeno…
Melanocortin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Open
Melanocortin receptors (provisional nomenclature as recommended by NC-IUPHAR [36]) are activated by members of the melanocortin family (α-MSH, β-MSH and γ-MSH forms; δ form is not found in mammals) and adrenocorticotrophin (ACTH). Endogeno…
View article: Melanocortin 2, 3 and 4 Receptor Gene Expressions are Downregulated in <scp>CD</scp>8<sup>+</sup> T Cytotoxic Lymphocytes and <scp>CD</scp>19<sup>+</sup> B Lymphocytes in Rheumatoid Arthritis Responding to <scp>TNF</scp>‐<i>α</i> Inhibition
Melanocortin 2, 3 and 4 Receptor Gene Expressions are Downregulated in <span>CD</span>8<sup>+</sup> T Cytotoxic Lymphocytes and <span>CD</span>19<sup>+</sup> B Lymphocytes in Rheumatoid Arthritis Responding to <span>TNF</span>‐<i>α</i> Inhibition Open
Melanocortin signalling in leucocyte subsets elicits anti‐inflammatory and immune tolerance inducing effects in animal experimental inflammation. In man, however, the effects of melanocortin signalling in inflammatory conditions have scarc…
CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins Open
Antifreeze protein (AFP) is an ice-binding protein that protects organisms from freezing in extremely cold environments. AFPs are found across a diverse range of species and, therefore, significantly differ in their structures. As there ar…
PepBio: predicting the bioactivity of host defense peptides Open
A large-scale QSAR study of host defense peptides sheds light on the origin of their bioactivities (antibacterial, anticancer, antiviral and antifungal).
Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking Open
Alzheimer’s disease (AD) is a chronic neurodegenerative disease which leads to the gradual loss of neuronal cells. Several hypotheses for AD exists (e.g., cholinergic, amyloid, tau hypotheses, etc.). As per the cholinergic hypothesis, the …
Peer Review #2 of "Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking (v0.1)" Open
Alzheimer's disease (AD) is a chronic neurodegenerative disease which leads to the gradual loss of neuronal cells.Several hypotheses for AD exists (e.g.cholinergic, amyloid, tau hypotheses, etc.).As per the cholinergic hypothesis, the defi…
View article: Resistin Gene Expression is Downregulated in <scp>CD</scp>4<sup>+</sup> T Helper Lymphocytes and <scp>CD</scp>14<sup>+</sup> Monocytes in Rheumatoid Arthritis Responding to <scp>TNF</scp>‐<i>α</i> Inhibition
Resistin Gene Expression is Downregulated in <span>CD</span>4<sup>+</sup> T Helper Lymphocytes and <span>CD</span>14<sup>+</sup> Monocytes in Rheumatoid Arthritis Responding to <span>TNF</span>‐<i>α</i> Inhibition Open
Rheumatoid arthritis ( RA ) is caused by complex interactions between immune cells and sustained by Th1 response cytokines. Resistin [resistance to insulin; (RETN) ] is an inflammatory cytokine, first discovered in murine adipocytes. In ma…
Roles of d-Amino Acids on the Bioactivity of Host Defense Peptides Open
Host defense peptides (HDPs) are positively-charged and amphipathic components of the innate immune system that have demonstrated great potential to become the next generation of broad spectrum therapeutic agents effective against a vast a…
Origin of aromatase inhibitory activity via proteochemometric modeling Open
Aromatase, the rate-limiting enzyme that catalyzes the conversion of androgen to estrogen, plays an essential role in the development of estrogen-dependent breast cancer. Side effects due to aromatase inhibitors (AIs) necessitate the pursu…
Peer Review #2 of "Origin of aromatase inhibitory activity via proteochemometric modeling (v0.2)" Open
Aromatase, the rate-limiting enzyme that catalyzes the conversion of androgen to estrogen, plays an essential role in the development of estrogen-dependent breast cancer.Side effects due to aromatase inhibitors (AIs) necessitate the pursui…