Jaroslaw Jedrych
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View article: The Overlapping Clinicopathological Presentations of Pityriasis Lichenoides and Mycosis Fungoides
The Overlapping Clinicopathological Presentations of Pityriasis Lichenoides and Mycosis Fungoides Open
Pityriasis lichenoides (PL) has traditionally been considered a benign cutaneous disorder with a diverse clinical presentation. This comprehensive literature review challenges that notion by exploring its histopathologic, immunopathologic,…
View article: A Trichoadenoma/Trichoepithelioma/Trichoblastoma-like Lesion in the Uterine Cervix Focally Mimics an Adenoid Basal Tumor
A Trichoadenoma/Trichoepithelioma/Trichoblastoma-like Lesion in the Uterine Cervix Focally Mimics an Adenoid Basal Tumor Open
The presence of ectodermal adnexal structures in the uterine cervix, including sebaceous glands, hair follicles, and sweat glands, has been well documented in the literature. In theory, there exists the possibility of developing cutaneous-…
View article: Improved overall survival with checkpoint inhibition and allogeneic transplantation in relapsed Hodgkin lymphoma
Improved overall survival with checkpoint inhibition and allogeneic transplantation in relapsed Hodgkin lymphoma Open
Patients with relapsed classic Hodgkin lymphomas (cHLs) receive salvage therapy with immune checkpoint inhibitors (ICIs) or chemotherapy (no-ICI). Patients responding to therapy often undergo consolidation with allogeneic blood or marrow t…
View article: Acquired Epidermodysplasia Verruciformis With <scp>HPV5 RNA</scp> Expression Using <scp>RNA</scp> Chromogenic In Situ Hybridization
Acquired Epidermodysplasia Verruciformis With <span>HPV5 RNA</span> Expression Using <span>RNA</span> Chromogenic In Situ Hybridization Open
View article: Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation
Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation Open
Proteomic profiling on other primary cicatricial alopecias, such as frontal fibrosing alopecia and lichen planopilaris, have suggested a T helper 1-mediated inflammatory pathway, but in central centrifugal cicatricial alopecia (CCCA), the …
View article: 222-N Analysis of pathologic features and efficacy outcomes with neoadjuvant nivolumab plus platinum-doublet chemotherapy for resectable non-small cell lung cancer in CheckMate 816
222-N Analysis of pathologic features and efficacy outcomes with neoadjuvant nivolumab plus platinum-doublet chemotherapy for resectable non-small cell lung cancer in CheckMate 816 Open
Background Pathologic response assessment after neoadjuvant treatment is the potential analog to radiographic response for advanced disease, with regard to study design, clinical care, and accelerated regulatory approvals. A standardized s…
View article: Association between pathologic response and survival after neoadjuvant therapy in lung cancer
Association between pathologic response and survival after neoadjuvant therapy in lung cancer Open
View article: Combinatorial biomarker for predicting outcomes to anti-PD-1 therapy in patients with metastatic clear cell renal cell carcinoma
Combinatorial biomarker for predicting outcomes to anti-PD-1 therapy in patients with metastatic clear cell renal cell carcinoma Open
View article: Table of Contents
Table of Contents Open
View article: Clear and Bright: An Elusive Cause of Hypoxemia
Clear and Bright: An Elusive Cause of Hypoxemia Open
View article: LBA50 Analysis of pathological features and efficacy outcomes with neoadjuvant nivolumab (N) plus platinum-doublet chemotherapy (C) for resectable non-small cell lung cancer (NSCLC) in CheckMate 816
LBA50 Analysis of pathological features and efficacy outcomes with neoadjuvant nivolumab (N) plus platinum-doublet chemotherapy (C) for resectable non-small cell lung cancer (NSCLC) in CheckMate 816 Open
View article: Generalized indeterminate cell histiocytosis successfully treated with methotrexate
Generalized indeterminate cell histiocytosis successfully treated with methotrexate Open
View article: Calciphylaxis Cutis Associated With Fibroblast Growth Factor Receptor (FGFR) Inhibitor Therapy: A New Challenge
Calciphylaxis Cutis Associated With Fibroblast Growth Factor Receptor (FGFR) Inhibitor Therapy: A New Challenge Open
Specific fibroblast growth factor receptor (FGFR) inhibitors have been developed to treat malignancies harboring fusions or rearrangements in FGFR2 or FGFR3. Here, we report a case of calciphylaxis cutis in association with FGFR inhibitor …
View article: Valsartan <scp>nano‐filaments</scp> alter mitochondrial energetics and promote faster healing in diabetic rat wounds
Valsartan <span>nano‐filaments</span> alter mitochondrial energetics and promote faster healing in diabetic rat wounds Open
Chronic wounds are a common and debilitating condition associated with aging populations that impact more than 6.5 million patients in the United States. We have previously demonstrated the efficacy of daily topical 1% valsartan in treatin…
View article: Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation
Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation Open
View article: Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization
Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization Open
View article: Porphyria cutanea tarda unmasked by supratherapeutic estrogen during gender-affirming hormone therapy
Porphyria cutanea tarda unmasked by supratherapeutic estrogen during gender-affirming hormone therapy Open
View article: Melanoma Ex Blue Nevus With GNA11 Mutation and BAP1 Loss: Case Report and Review of the Literature
Melanoma Ex Blue Nevus With GNA11 Mutation and BAP1 Loss: Case Report and Review of the Literature Open
Cutaneous melanomas may demonstrate a variety of histopathological features and genetic abnormalities. Melanomas that arise in the setting of blue nevi, also known as “malignant blue nevus” or melanoma ex blue nevus (MBN), share a similar …
View article: Topiramate-induced reactive granulomatous dermatitis
Topiramate-induced reactive granulomatous dermatitis Open
The clinicopathologic spectrum of reactive granulomatous dermatitis (RGD) includes 4 subtypes: palisaded neutrophilic and granulomatous, interstitial granulomatous, polycyclic (granuloma annulare–like), and drug-induced reactive granulomat…
View article: Grover’s Disease Treated With Total Skin Electron Beam Radiotherapy
Grover’s Disease Treated With Total Skin Electron Beam Radiotherapy Open
Persistent Grover's disease can cause significant symptoms of pruritus thereby decreasing quality of life. Many patients undergo successful conservative management of their disease; however, a subset of patients is recalcitrant despite mul…
View article: A challenging diagnosis of penile sarcomatoid squamous cell carcinoma
A challenging diagnosis of penile sarcomatoid squamous cell carcinoma Open
We report a patient with penile sarcomatoid squamous cell carcinoma (SCC) initially misdiagnosed as condyloma acuminatum. Sarcomatoid SCC is a rare, aggressive, biphasic cancer that often presents a diagnostic challenge and carries a poor …
View article: Therapeutic and prognostic significance of <scp>PARP</scp>‐1 in advanced mycosis fungoides and Sezary syndrome
Therapeutic and prognostic significance of <span>PARP</span>‐1 in advanced mycosis fungoides and Sezary syndrome Open
While mycosis fungoides ( MF ) is typically an indolent malignancy, it may infrequently undertake an aggressive course. We used proteomic analyses to identify a biomarker of the aggressive course of MF . Results of this investigation demon…
View article: Early-Onset Basal Cell Carcinoma in Young Female Endurance Athletes: A Report of Three Cases
Early-Onset Basal Cell Carcinoma in Young Female Endurance Athletes: A Report of Three Cases Open
No abstract available.
View article: Early-Onset Basal Cell Carcinoma in Young Female Endurance Athletes: A Report of Three Cases
Early-Onset Basal Cell Carcinoma in Young Female Endurance Athletes: A Report of Three Cases Open
No abstract available.
View article: Multifocal primary cutaneous nodular amyloidosis
Multifocal primary cutaneous nodular amyloidosis Open
Nodular cutaneous amyloidosis (NCA), the least common form of primary cutaneous amyloidosis, is characterized clinically by waxy, purpuric plaques and nodules and histologically by amyloid deposits in the dermis and subcutaneous tissue. We…