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View article: Harmonized low‐dose computed tomographic protocols for quantitative lung imaging using dose modulation and advanced reconstructions
Harmonized low‐dose computed tomographic protocols for quantitative lung imaging using dose modulation and advanced reconstructions Open
Background Quantitative computed tomography (QCT) lung imaging is employed in many multi‐center studies. Standardized protocols have used fixed volumetric CT dose index (CTDIvol) adjusted for body mass index to minimize dose while accounti…
View article: Comparison of quantitative lung measures in low dose energy-integrating detector and photon-counting detector chest CT with an anthropomorphic phantom
Comparison of quantitative lung measures in low dose energy-integrating detector and photon-counting detector chest CT with an anthropomorphic phantom Open
Photon-counting detector (PCD) computed tomography (CT) promises improved resolution and contrast at reduced x-ray dose compared to energy-integrating detector (EID) CT. Our objective is to determine the parameters that achieve robust accu…
View article: Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis
Ferret model of bleomycin-induced lung injury shares features of human idiopathic pulmonary fibrosis Open
Idiopathic pulmonary fibrosis (IPF) is a debilitating lung disease with limited therapeutic options. The development of effective therapies has been hindered by the lack of models that recapitulate key features of human disease. Here we re…
View article: Task‐based validation and application of a scanner‐specific CT simulator using an anthropomorphic phantom
Task‐based validation and application of a scanner‐specific CT simulator using an anthropomorphic phantom Open
Background Quantitative analysis of computed tomography (CT) images traditionally utilizes real patient data that can pose challenges with replicability, efficiency, and radiation exposure. Instead, virtual imaging trials (VITs) can overco…
View article: Inter- and intra-scan variability for lung imaging quantifications via CT
Inter- and intra-scan variability for lung imaging quantifications via CT Open
CT imaging provides physicians valuable insights when diagnosing disease in a clinical setting. In order to provide an accurate diagnosis, is it important to have a high accuracy with controlled variability across CT scans from different s…
View article: Scanner-specific validation of a CT simulator using a COPD-emulated anthropomorphic phantom
Scanner-specific validation of a CT simulator using a COPD-emulated anthropomorphic phantom Open
Traditional methods of quantitative analysis of CT images typically involve working with patient data, which is often expensive and limited in terms of ground truth. To counter these restrictions, quantitative assessments can instead be ma…
View article: A Novel Device to Measure 3D MTF Accounting for CT Scanner, Protocol and the Thoracic Environment
A Novel Device to Measure 3D MTF Accounting for CT Scanner, Protocol and the Thoracic Environment Open
Purpose: Modulation Transfer Function (MTF) serves to evaluate Computed Tomography (CT) scanner performance.It typically uses a bead-based phantom with scanning in an engineering-mode and does not reflect clinical scanning protocols.Furthe…