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View article: Schizophrenia, Bipolar, or Major Depressive Disorder and Postacute Sequelae of COVID-19
Schizophrenia, Bipolar, or Major Depressive Disorder and Postacute Sequelae of COVID-19 Open
Importance Given the increased vulnerability to COVID-19 among those with a serious mental illness (SMI), it remains unclear whether these individuals face a higher risk of developing postacute sequelae of SARS-CoV-2 (PASC). Understanding …
View article: The pharyngeal phase of swallowing controls deglutitive inhibition
The pharyngeal phase of swallowing controls deglutitive inhibition Open
Deglutitive inhibition is caused by central inhibition of ongoing esophageal phase of swallowing during the new pharyngeal phase by short-term cessation of striated muscle peristalsis and longer-term reduction in smooth muscle peristaltic …
View article: Safeguarding Brand and Platform Credibility Through AI-Based Multi-Model Fake Profile Detection
Safeguarding Brand and Platform Credibility Through AI-Based Multi-Model Fake Profile Detection Open
The proliferation of fake profiles on social media presents critical cybersecurity and misinformation challenges, necessitating robust and scalable detection mechanisms. Such profiles weaken consumer trust, reduce user engagement, and ulti…
View article: The Effect of Specialized Exercises Based on Mechanical Principles on Diagonal Attacks from Positions (2) and (4) Among Third-Year Students in Volleyball
The Effect of Specialized Exercises Based on Mechanical Principles on Diagonal Attacks from Positions (2) and (4) Among Third-Year Students in Volleyball Open
Researchers and specialists in the fields of educational sciences strive to enhance the academic level of their students. Among the most prominent of these sciences is sports science, which encompasses various specializations, curricula, a…
View article: Leveraging Data Mining Approaches For Enhanced Malware Classification And Digital Forensic Investigation
Leveraging Data Mining Approaches For Enhanced Malware Classification And Digital Forensic Investigation Open
The increasing frequency and sophistication of cyberattacks have created the need for advanced techniques to classify and analyze malware. This research proposes a novel data mining-based algorithm for effective malware classification and …
View article: Public health emergency accelerated research response—the Clinical and Translational Science Institute of Southeast Wisconsin COVID-19 research initiative
Public health emergency accelerated research response—the Clinical and Translational Science Institute of Southeast Wisconsin COVID-19 research initiative Open
Introduction In March 2020, the National Center for Advancing Translational Sciences—Clinical and Translational Science Awards (CTSA) Program issued an urgent “Call to Action,” requesting CTSA hubs to accelerate clinical and translational …
View article: Kidney Function Following COVID-19 in Children and Adolescents
Kidney Function Following COVID-19 in Children and Adolescents Open
Importance It remains unclear whether children and adolescents with SARS-CoV-2 infection are at heightened risk for long-term kidney complications. Objective To investigate whether SARS-CoV-2 infection is associated with an increased risk …
View article: Pediatric Gastrointestinal Tract Outcomes During the Postacute Phase of COVID-19
Pediatric Gastrointestinal Tract Outcomes During the Postacute Phase of COVID-19 Open
Importance The profile of gastrointestinal (GI) tract outcomes associated with the postacute and chronic phases of COVID-19 in children and adolescents remains unclear. Objective To investigate the risks of GI tract symptoms and disorders …
View article: Correlation of deglutitive striated esophagus motor function and pharyngeal phase swallowing biomechanical events
Correlation of deglutitive striated esophagus motor function and pharyngeal phase swallowing biomechanical events Open
Background The functional relationship of striated esophagus (St.Eso) motor function with pharyngeal deglutitive biomechanical events has not been systematically studied. The aim of this study was to determine the spatio‐temporal character…
View article: Translational science and related disciplines
Translational science and related disciplines Open
Translational research moves scientific discoveries and innovations across the development spectrum for a particular target or disease, trying to bridge in a multidisciplinary fashion the gap between laboratory scientific discoveries and p…
View article: The Evaluation Of The Serum Level Of Vimentin In Chronic Kidney Disease Patients In AL-Najaf Province/Iraq
The Evaluation Of The Serum Level Of Vimentin In Chronic Kidney Disease Patients In AL-Najaf Province/Iraq Open
Chronic Kidney Disease (CKD) is a complex condition characterized by kidney damage or decreased function, leading to a range of complications. These include cardiovascular risk, immune dysfunction, and lung disease. The study aims to inves…
View article: Adult zymosan re-exposure exacerbates the molecular alterations in the brainstem rostral ventromedial medulla of rats with early life zymosan-induced cystitis
Adult zymosan re-exposure exacerbates the molecular alterations in the brainstem rostral ventromedial medulla of rats with early life zymosan-induced cystitis Open
Recent evidence suggests that the descending modulatory pathways from the brainstem rostral ventromedial medulla (RVM) are important for bladder inflammatory pain. This study aimed to identify the long-term molecular changes in RVM neurons…
View article: Managing the risks and benefits of clinical research in response to a pandemic
Managing the risks and benefits of clinical research in response to a pandemic Open
Introduction: The coronavirus disease 2019 (COVID-19) created major disruptions at academic centers and healthcare systems globally. Clinical and Translational Science Awards (CTSA) fund hubs supported by the National Center for Advancing …
View article: Biomechanical increase in cervical esophageal wall tension during peristalsis
Biomechanical increase in cervical esophageal wall tension during peristalsis Open
Circumferential tension of cervical esophagus (CTE) increases during esophageal peristalsis. CTE response is correlated with distal longitudinal tension on cervical esophagus during esophageal peristalsis but not laryngeal elevation or eso…
View article: Effect of inter‐swallow interval on striated esophagus peristalsis; a comparative study with smooth muscle<scp>esophagus</scp>
Effect of inter‐swallow interval on striated esophagus peristalsis; a comparative study with smooth muscle<span>esophagus</span> Open
Background Effect of inter‐swallow interval on the contractility of smooth muscle esophagus is well‐documented. However, the effects on peristalsis of the striated esophagus have not been systematically studied. A better understanding of s…
View article: Biomechanical effects of esophageal elongation on the circumferential tension of the cervical esophagus in vivo
Biomechanical effects of esophageal elongation on the circumferential tension of the cervical esophagus in vivo Open
Physical or physiological esophageal elongation increases esophageal circumferential active or passive tension by a biomechanical process, which causes a decrease in esophageal circumferential elasticity. This increased stiffness of the es…
View article: Team science criteria and processes for promotion and tenure of Health Science University Faculty
Team science criteria and processes for promotion and tenure of Health Science University Faculty Open
Although team science has expanded with far-reaching benefits, universities generally have not established criteria to recognize its value in faculty promotion and tenure. This paper recommends how institutions might weigh a faculty member…
View article: Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients Open
ClinicalTrials.gov Identifier: NCT04364737.
View article: Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications
Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications Open
The EAS and PRM both exhibit fatigue with contractions only against a resistive load. These findings may guide the development of appropriate exercise regimens to target specific muscles involved in fecal continence.
View article: Identification and characterization of rostral ventromedial medulla neurons synaptically connected to the urinary bladder afferents in female rats with or without neonatal cystitis
Identification and characterization of rostral ventromedial medulla neurons synaptically connected to the urinary bladder afferents in female rats with or without neonatal cystitis Open
The neurons in the rostral ventromedial medulla (RVM) play a major role in pain modulation. We have previously shown that early‐life noxious bladder stimuli in rats resulted in an overall spinal GABAergic disinhibition and a long‐lasting b…
View article: Variables influencing manometric parameters of deglutitive and non‐deglutitive upper esophageal sphincter: A study of 89 asymptomatic participants
Variables influencing manometric parameters of deglutitive and non‐deglutitive upper esophageal sphincter: A study of 89 asymptomatic participants Open
Background High‐resolution manometry overcomes limitations imposed by axial and radial asymmetry as well as swallow and respiration‐induced movement of the upper esophageal sphincter (UES), allowing for its reliable use in evaluation of dy…
View article: Characteristics of high‐resolution esophageal manometry in children without dysphagia
Characteristics of high‐resolution esophageal manometry in children without dysphagia Open
Background The absence of high‐resolution esophageal manometry (HREM) norms in pediatrics limits the assessment of children with dysphagia. This study aimed to describe HREM parameters in a cohort of children without dysphagia. Methods Chi…
View article: Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device
Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device Open
Fecal incontinence is a distressing disorder with a mainstay of treatment being pelvic floor muscle exercises. However, none of these exercises has proven occurrence of fatigability, which is an important prerequisite for successful muscle…