Jasmin Jäger
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View article: Fading SARS-CoV-2 humoral VOC cross-reactivity and sustained cellular immunity in convalescent children and adolescents
Fading SARS-CoV-2 humoral VOC cross-reactivity and sustained cellular immunity in convalescent children and adolescents Open
View article: Fading SARS-CoV-2 humoral VOC cross-reactivity versus sustained cellular immunity in convalescent children and adolescents
Fading SARS-CoV-2 humoral VOC cross-reactivity versus sustained cellular immunity in convalescent children and adolescents Open
Cross-reactive cellular and humoral immunity can substantially contribute to antiviral defense against SARS-CoV-2 variants of concern (VOC). While the adult SARS-CoV-2 cellular and humoral immunity and its cross-recognition potential again…
View article: Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19
Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19 Open
The role of adaptive SARS-CoV-2 specific immunity in post-acute sequelae of COVID-19 (PASC) is not well explored, although a growing population of convalescent COVID-19 patients with manifestation of PASC is observed. We analyzed the SARS-…
View article: Fading SARS-CoV-2 humoral and sustained cellular immunity in convalescent children and adolescents
Fading SARS-CoV-2 humoral and sustained cellular immunity in convalescent children and adolescents Open
Cross-reactive cellular and humoral immunity can substantially contribute to antiviral defense against SARS-CoV-2 variants of concern (VOC). While the adult SARS-CoV-2 cellular and humoral immunity and its cross-recognition potential again…
View article: Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A
Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A Open
View article: Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria
Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria Open
Significance Severe heat stress causes massive protein loss by aggregation ultimately causing cell death. Cellular survival relies on protein disaggregation mediated by the Hsp70-ClpB (Hsp100) bichaperone system in most bacteria. Pseudomon…
View article: Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control
Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control Open
Ring-forming AAA+ chaperones exert ATP-fueled substrate unfolding by threading through a central pore. This activity is potentially harmful requiring mechanisms for tight repression and substrate-specific activation. The AAA+ chaperone Clp…
View article: Author response: Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control
Author response: Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control Open
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Ring-forming AAA+ chaperones …
View article: Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control
Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control Open
Ring-forming AAA+ chaperones exert ATP-fueled substrate unfolding by threading through a central pore. This activity is potentially harmful requiring mechanisms for tight repression and substrate-specific activation. The AAA+ chaperone Clp…