Jasmina Kravić
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View article: Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes Open
To extend understanding of the genetic architecture and molecular basis of type 2 diabetes (T2D), we conducted a meta-analysis of genetic variants on the Metabochip involving 34,840 cases and 114,981 controls, overwhelmingly of European de…
View article: Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study
Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study Open
OBJECTIVE Cardiovascular disease (CVD) risk prediction represents an increasing clinical challenge in the treatment of diabetes. We used a panel of vascular imaging, functional assessments, and biomarkers reflecting different disease mecha…
View article: Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Open
View article: Early metabolic markers identify potential targets for the prevention of type 2 diabetes
Early metabolic markers identify potential targets for the prevention of type 2 diabetes Open
View article: Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Open
Identification of coding variant associations for complex diseases offers a direct route to biological insight, but is dependent on appropriate inference concerning the causal impact of those variants on disease risk. We aggregated coding …
View article: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Open
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in or near KCNQ1. 'Credibl…
View article: Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci Open