Jason Abbott
YOU?
Author Swipe
View article: An integrated multimodal approach to drug repurposing in endometriosis, using ROR1 as a target
An integrated multimodal approach to drug repurposing in endometriosis, using ROR1 as a target Open
Background Endometriosis is a chronic, heterogeneous disease with limited non-hormonal treatment options. Drug repurposing provides an accelerated route to identify safe, tolerable, and potentially effective therapies for endometriosis. Re…
View article: Patient-derived epithelial cell organoids mimic the phenotypic complexity of endometriosis subtypes
Patient-derived epithelial cell organoids mimic the phenotypic complexity of endometriosis subtypes Open
STUDY QUESTION Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology? SUMMARY ANSWER…
View article: “This is how we do it” Anaesthesia for uterine transplant and associated surgeries: the Australian-Swedish collaborative protocol
“This is how we do it” Anaesthesia for uterine transplant and associated surgeries: the Australian-Swedish collaborative protocol Open
Uterine transplantation represents a groundbreaking fertility treatment for individuals with uterine factor infertility. Since the first successful live birth from uterine transplantation in 2014, surgical technique and outcomes have been …
View article: Cumulative live birth rates in women with endometriosis undergoing ART treatment
Cumulative live birth rates in women with endometriosis undergoing ART treatment Open
STUDY QUESTION How do cumulative live birth rates (CLBRs) in women with endometriosis compare to those with other infertility diagnoses undergoing ART? SUMMARY ANSWER Women with endometriosis as the sole cause of infertility achieved highe…
View article: Co-designing, evaluating and implementing online supportive care for endometriosis in Australia: study protocol for the hybrid type 1 effectiveness, cost-effectiveness and implementation randomised controlled trial of the CodeEndo program
Co-designing, evaluating and implementing online supportive care for endometriosis in Australia: study protocol for the hybrid type 1 effectiveness, cost-effectiveness and implementation randomised controlled trial of the CodeEndo program Open
Introduction Endometriosis is a chronic condition affecting up to 11% of people presumed female at birth by the age of 44 years, characterised by the growth of tissue similar to the lining of the uterus on other organs. Endometriosis signi…
View article: “A dose of relief?”: Results of an international survey exploring self-reported effectiveness, dose and dosage forms of cannabis for endometriosis pain and related symptoms
“A dose of relief?”: Results of an international survey exploring self-reported effectiveness, dose and dosage forms of cannabis for endometriosis pain and related symptoms Open
Background Endometriosis is a common, chronic inflammatory condition impacting 10–14% of reproductive aged females. Common symptoms include severe dysmenorrhea, pelvic pain and fatigue. Current symptom management options are often unsatisf…
View article: The first live term birth following uterus transplantation in Australia
The first live term birth following uterus transplantation in Australia Open
Objective To report the first live birth following uterus transplantation in Australia. Study design Case report. Setting, participant The first participant in the uterus transplantation research study program at the Royal Hospital for Wom…
View article: Endometriosis is not the endometrium: Reviewing the over-representation of eutopic endometrium in endometriosis research
Endometriosis is not the endometrium: Reviewing the over-representation of eutopic endometrium in endometriosis research Open
As a heterogenous disease with likely multiple pathogeneses and as-yet-undefined subtypes, progress in endometriosis treatment is currently limited by a lack of appropriate models and cohorts for research. Almost half of all publicly avail…
View article: Comment on Jankovic et al. Understanding the Benefits of CO2 Laser Treatment for Vulvovaginal Atrophy. Medicina 2024, 60, 1059
Comment on Jankovic et al. Understanding the Benefits of CO2 Laser Treatment for Vulvovaginal Atrophy. Medicina 2024, 60, 1059 Open
We write with concerns regarding the recent publication of “Understanding the Benefits of CO2 Laser Treatment for Vulvovaginal Atrophy” [...]
View article: ‘In the weeds’: navigating the complex concerns, challenges and choices associated with medicinal cannabis consumption for endometriosis
‘In the weeds’: navigating the complex concerns, challenges and choices associated with medicinal cannabis consumption for endometriosis Open
People with endometriosis report consuming cannabis to manage their symptoms. Given the range of differing legalities and access pathways across the world, this study aimed to investigate the drivers and barriers to cannabis use worldwide.…
View article: Patterns of health service use before and after diagnosis of endometriosis: a data linkage prospective cohort study
Patterns of health service use before and after diagnosis of endometriosis: a data linkage prospective cohort study Open
STUDY QUESTION What are the patterns of health service use (HSU) before and after endometriosis diagnosis? SUMMARY ANSWER Women with endometriosis had higher rates of visits to general practitioners (GPs), specialists, and diagnostic imagi…
View article: Perinatal and infant outcomes after assisted reproductive technology treatment for endometriosis alone compared with other causes of infertility: a data linkage cohort study
Perinatal and infant outcomes after assisted reproductive technology treatment for endometriosis alone compared with other causes of infertility: a data linkage cohort study Open
Reassuringly, perinatal and infant outcomes are generally comparable for ART-conceived infants born to mothers with endometriosis alone and those with other causes of infertility when considered as a singular disease entity. Larger studies…
View article: Anatomical neuromuscular variations determined by magnetic resonance imaging in chronic pelvic pain
Anatomical neuromuscular variations determined by magnetic resonance imaging in chronic pelvic pain Open
Background: The diagnosis of neuromuscular pelvic pain is challenging. Despite the increasing use of magnetic resonance imaging (MRI) in the assessment of pudendal neuralgia, there are limited data describing radiological variations of the…
View article: A scoping review of participant reported outcome measures assessed during live and simulated surgical procedures
A scoping review of participant reported outcome measures assessed during live and simulated surgical procedures Open
Anxiety, stress, and workload have been measured in surgeons although the most appropriate to monitor surgeon wellbeing is not clear.
View article: Medical management of endometriosis
Medical management of endometriosis Open
Purpose of review While laparoscopic surgery plays a key role in the management of endometriosis, symptoms commonly recur, and repeat surgery comes with increased risk. Medical management, including hormonal and nonhormonal treatment, is v…
View article: A study protocol for live and deceased donor uterus transplantation as a treatment for women with uterine factor infertility
A study protocol for live and deceased donor uterus transplantation as a treatment for women with uterine factor infertility Open
Aim Uterus transplantation (UTx) is an emerging treatment option for women with uterine factor infertility (UFI) or the absence of a functional uterus. This is the study protocol for the first human UTx clinical trial in Australia. Materia…
View article: A survey of cost, access and outcomes for cannabinoid‐based medicinal product use by Australians with endometriosis
A survey of cost, access and outcomes for cannabinoid‐based medicinal product use by Australians with endometriosis Open
People with endometriosis use cannabis to manage their symptoms. This study aimed to identify costs, modes of administration, product composition, and self‐reported effectiveness for those accessing medicinal cannabis in Australia. There w…
View article: Perfusion magnetic resonance imaging in Asherman syndrome
Perfusion magnetic resonance imaging in Asherman syndrome Open
Background Microvascular scarring compromises the functionality of the endometrium, and vascular flow at the junctional zone (JZ) may be the key to understanding poor reproductive outcomes in women with Asherman syndrome (AS). Aims To inve…
View article: Social Media, Endometriosis, and Evidence-Based Information: An Analysis of Instagram Content
Social Media, Endometriosis, and Evidence-Based Information: An Analysis of Instagram Content Open
Social media platforms are used for support and as resources by people from the endometriosis community who are seeking advice about diagnosis, education, and disease management. However, little is known about the scientific accuracy of in…
View article: Surgeon reported measures of stress and anxiety prior to and after elective gynecological surgery
Surgeon reported measures of stress and anxiety prior to and after elective gynecological surgery Open
Introduction Performing surgical procedures is a recognized source of stress for surgeons. Vocational stress is an important contributor to performance, patient care, and burnout with dispositional and environmental factors contributing. A…
View article: Non‐invasive tests for endometriosis are here; how reliable are they, and what should we do with the results?
Non‐invasive tests for endometriosis are here; how reliable are they, and what should we do with the results? Open
A reliable non‐invasive biomarker for endometriosis is highly likely in the coming years. In the lead‐up to this, clinicians need to be aware of commercially available tests as they become accessible, be aware of the level of evidence to s…
View article: The Place of Cannabinoids in the Treatment of Gynecological Pain
The Place of Cannabinoids in the Treatment of Gynecological Pain Open
Cannabis sativa (L), a plant with an extensive history of medicinal usage across numerous cultures, has received increased attention over recent years for its therapeutic potential for gynecological disorders such as endometriosis, chronic…
View article: ‘A glimmer of hope’: perceptions, barriers, and drivers for medicinal cannabis use amongst Australian and New Zealand people with endometriosis – a qualitative study
‘A glimmer of hope’: perceptions, barriers, and drivers for medicinal cannabis use amongst Australian and New Zealand people with endometriosis – a qualitative study Open
Previous quantitative research has shown that cannabis use, mostly illicit, is used for symptom management amongst those with endometriosis living in Australia or New Zealand, but the drivers and barriers for use of legal, medicinal cannab…