Jason C. Woods
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View article: Unraveling <i>Streptococcus pyogenes</i> Carriage: Genomic and Transcriptomic Insights from Acute and Post-Treatment Phases
Unraveling <i>Streptococcus pyogenes</i> Carriage: Genomic and Transcriptomic Insights from Acute and Post-Treatment Phases Open
The carrier state of Streptococcus pyogenes (Group A Streptococcus, GAS), is defined by the presence of the organism without symptoms or an immune response. Carriage poses challenges for clinical management and contributes to transmission …
View article: Tracheal Work of Breathing in Neonates With Tracheoesophageal Fistula Before and After Surgical Repair via Computational Fluid Dynamics Assessment
Tracheal Work of Breathing in Neonates With Tracheoesophageal Fistula Before and After Surgical Repair via Computational Fluid Dynamics Assessment Open
4 Case Series.
View article: Hydroxyapatite microspheres induce durable pleurodesis and are rapidly cleared by pleural osteoclasts
Hydroxyapatite microspheres induce durable pleurodesis and are rapidly cleared by pleural osteoclasts Open
Talc pleurodesis is highly effective for preventing recurrence of pneumothorax and pleural effusion, but it can be complicated by dissemination, acute lung injury, lead exposure, and foreign body-induced chronic inflammation and pain. Our …
View article: Comparative evaluation of supervised and unsupervised deep learning strategies for denoising hyperpolarized <scp> <sup>129</sup> Xe </scp> lung <scp>MRI</scp>
Comparative evaluation of supervised and unsupervised deep learning strategies for denoising hyperpolarized <span> <sup>129</sup> Xe </span> lung <span>MRI</span> Open
Purpose Reduced signal‐to‐noise ratio (SNR) in hyperpolarized 129 Xe MR images can affect accurate quantification for research and diagnostic evaluations. Thus, this study explores the application of supervised deep learning (DL) denoising…
View article: High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study
High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study Open
Background Pulmonary complications are a major cause of morbidity and mortality in pediatric and young adult hematopoietic stem cell transplant (HSCT) recipients. The impact of preexisting lung dysfunction on posttransplant outcomes remain…
View article: Detection of Post- Hematopoietic StemCell Transplant Bronchiolitis Obliterans Syndrome (BOS) – The Use of Airway Oscillometry
Detection of Post- Hematopoietic StemCell Transplant Bronchiolitis Obliterans Syndrome (BOS) – The Use of Airway Oscillometry Open
View article: Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls
Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls Open
The DDI is applicable to functional 129Xe-MRI and PREFUL-MRI data providing complementary information to VDP by assessing defect distribution rather than defect size. It shows meaningful clinimetric properties and improves with …
View article: Investigation of ventilation-coupled high energy density sensible thermal energy storage
Investigation of ventilation-coupled high energy density sensible thermal energy storage Open
View article: Community respiratory viruses are generally well-tolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study
Community respiratory viruses are generally well-tolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study Open
Not available.
View article: A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging
A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging Open
Hyperpolarized (HP) gas pulmonary MR ventilation images are typically quantified using ventilation defect percent (VDP); however, the test‐retest variability of VDP has not been systematically established in multi‐center trials. Herein, we…
View article: Quantifying spatial and dynamic lung abnormalities with <scp>3D PREFUL FLORET UTE</scp> imaging: A feasibility study
Quantifying spatial and dynamic lung abnormalities with <span>3D PREFUL FLORET UTE</span> imaging: A feasibility study Open
Purpose Pulmonary MRI faces challenges due to low proton density, rapid transverse magnetization decay, and cardiac and respiratory motion. The fermat‐looped orthogonally encoded trajectories (FLORET) sequence addresses these issues with h…
View article: Ice Storage Model-Predictive Control in an Office Building With Pv: Scenario, Error and Sensitivity Analysis
Ice Storage Model-Predictive Control in an Office Building With Pv: Scenario, Error and Sensitivity Analysis Open
View article: New frontiers in asthma chest imaging
New frontiers in asthma chest imaging Open
Modern pulmonary imaging can reveal underlying pathologic and pathophysiologic changes in the lungs of people with asthma, with important clinical implications. A multitude of imaging modalities, including computed tomography, magnetic res…
View article: Pulmonary <scp>MRI</scp> in Newborns and Children
Pulmonary <span>MRI</span> in Newborns and Children Open
Lung MRI is an important tool in the assessment and monitoring of pediatric and neonatal lung disorders. MRI can provide both similar and complementary image contrast to computed tomography for imaging the lung macrostructure, and beyond t…
View article: Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia
Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia Open
Background Tracheomalacia (TM) is common in infants with bronchopulmonary dysplasia (BPD) and associated with respiratory morbidity. Assessment of TM was historically via bronchoscopy, but recent studies demonstrate that ultrashort echo‐ti…
View article: <scp><sup>129</sup>Xe</scp> Image Processing Pipeline: An open‐source, graphical user interface application for the analysis of <scp>hyperpolarized <sup>129</sup>Xe MRI</scp>
<span><sup>129</sup>Xe</span> Image Processing Pipeline: An open‐source, graphical user interface application for the analysis of <span>hyperpolarized <sup>129</sup>Xe MRI</span> Open
Purpose Hyperpolarized 129 Xe MRI presents opportunities to assess regional pulmonary microstructure and function. Ongoing advancements in hardware, sequences, and image processing have helped it become increasingly adopted for both resear…
View article: Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized <scp><sup>129</sup>Xenon MRI</scp>
Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized <span><sup>129</sup>Xenon MRI</span> Open
Background Hyperpolarized 129 Xe MRI assesses lung ventilation, often using the ventilation defect percentage (VDP). Unlike VDP, defect distribution index (DDI) quantifies spatial clustering of defects. Purpose To quantify spatial distribu…
View article: A Review of Modeling Approaches for Predicting Frost Growth and Defrosting on Tube-Fin Heat Exchangers: Preprint
A Review of Modeling Approaches for Predicting Frost Growth and Defrosting on Tube-Fin Heat Exchangers: Preprint Open
Frost formation and growth on the evaporator surface is a common process that deteriorates the air-refrigerant heat transfer and restricts airflow. This degrades the performance of the vapor compression system by increasing temperature lif…
View article: Same‐Day Repeatability and 28‐Day Reproducibility of Xenon <scp>MRI</scp> Ventilation in Children With Cystic Fibrosis in a Multi‐Site Trial
Same‐Day Repeatability and 28‐Day Reproducibility of Xenon <span>MRI</span> Ventilation in Children With Cystic Fibrosis in a Multi‐Site Trial Open
Background MRI with xenon‐129 gas (Xe MRI) can assess airflow obstruction and heterogeneity in lung diseases. Specifically, Xe MRI may represent a sensitive modality for future therapeutic trials of cystic fibrosis (CF) therapies. The repr…
View article: High‐quality <scp>FLORET UTE</scp> imaging for clinical translation
High‐quality <span>FLORET UTE</span> imaging for clinical translation Open
Purpose To develop a robust 3D ultrashort‐TE (UTE) protocol that can reproducibly provide high‐quality images, assessed by the ability to yield clinically diagnostic images, and is suitable for clinical translation. Theory and Methods Buil…
View article: Open-cycle thermochemical energy storage for building space heating: Practical system configurations and effective energy density
Open-cycle thermochemical energy storage for building space heating: Practical system configurations and effective energy density Open
View article: The impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol
The impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol Open
Background Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are prevalent disease complications in people with cystic fibrosis. These understudied comorbidities significantly impact quality of life. The impact of highly effectiv…
View article: Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI
Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI Open
Background . Thoracoabdominal MRI is limited by respiratory motion, especially in populations who cannot perform breath-holds. One approach for reducing motion blurring in radially-acquired MRI is respiratory gating. Straightforward ‘hard-…
View article: To Freeze or Not to Freeze: Model-Predictive vs. Schedule-Based Control of an Ice-Based Thermal Energy Storage System
To Freeze or Not to Freeze: Model-Predictive vs. Schedule-Based Control of an Ice-Based Thermal Energy Storage System Open
View article: Tracheomalacia Reduces Aerosolized Drug Delivery to the Lung
Tracheomalacia Reduces Aerosolized Drug Delivery to the Lung Open
Rationale: Neonates with respiratory issues are frequently treated with aerosolized medications to manage lung disease or facilitate airway clearance. Dynamic tracheal collapse (tracheomalacia [TM]) is a common comorbidity in…
View article: Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging
Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging Open
Rationale Bronchopulmonary dysplasia (BPD) is the most common long term pulmonary morbidity in premature infants and is characterized by impaired lung growth and development. We hypothesized that lung mass growth is a critical factor in de…
View article: 302 Clinical response to modulator therapy in patients homozygous for G27V CFTR
302 Clinical response to modulator therapy in patients homozygous for G27V CFTR Open
View article: 57 Bronchoscopy sampling finds that intra-lung bacterial migration contributes to persistent Pseudomonas aeruginosa infection after elexacaftor-tezacaftor-ivacaftor
57 Bronchoscopy sampling finds that intra-lung bacterial migration contributes to persistent Pseudomonas aeruginosa infection after elexacaftor-tezacaftor-ivacaftor Open
View article: 129 Response in imaging and lung function outcomes in the HyPOINT study
129 Response in imaging and lung function outcomes in the HyPOINT study Open
View article: Initial feasibility and challenges of hyperpolarized <scp><sup>129</sup>Xe</scp> MRI in neonates with bronchopulmonary dysplasia
Initial feasibility and challenges of hyperpolarized <span><sup>129</sup>Xe</span> MRI in neonates with bronchopulmonary dysplasia Open
Purpose The underlying functional and microstructural lung disease in neonates who are born preterm (bronchopulmonary dysplasia, BPD) remains poorly characterized. Moreover, there is a lack of suitable techniques to reliably assess lung fu…