Jason Chhen
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View article: Characterization of Two Novel Inhibitors of the Mycobacterium tuberculosis Cytochrome <i>bc</i> <sub>1</sub> Complex
Characterization of Two Novel Inhibitors of the Mycobacterium tuberculosis Cytochrome <i>bc</i> <sub>1</sub> Complex Open
Drug-resistant tuberculosis is a global health care threat calling for novel effective treatment options. Here, we report on two novel cytochrome bc 1 inhibitors (MJ-22 and B6) targeting the Mycobacterium tuberculosis respiratory chain wit…
View article: Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages Open
Infections with viral pathogens are widespread and can cause a variety of different diseases. In-depth knowledge about viral triggers initiating an immune response is necessary to decipher viral pathogenesis. Inflammasomes, as part of the …