Jason Lee
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View article: Novel cooling vest with personal protective equipment alleviates heat strain without increasing metabolic demands in the heat
Novel cooling vest with personal protective equipment alleviates heat strain without increasing metabolic demands in the heat Open
OBJECTIVE: Wearing medical personal protective equipment (PPE) substantially increases heat strain by elevating metabolic heat production while impairing heat dissipation. Cooling vests are a practical countermeasure, yet their efficiency …
View article: A Systematic Review of Heat Health Warning Systems: Enhancing the Framework Towards Effective Health Outcomes
A Systematic Review of Heat Health Warning Systems: Enhancing the Framework Towards Effective Health Outcomes Open
Purpose of Review Heat Health Warning Systems (HHWS) reduce heat-related morbidity and mortality. We reviewed scientific studies on HHWS that use meteorological variables, local climate-epidemiological evidence, personalization, and built …
View article: Ecological assessment of extreme temperature and fine particulate matter (pm2.5) impact on diabetes service and outcomes in Thailand
Ecological assessment of extreme temperature and fine particulate matter (pm2.5) impact on diabetes service and outcomes in Thailand Open
Background Environmental changes, such as extreme heat and air pollution, are assumed to exacerbate chronic conditions like diabetes and increase demand for related health services. This study investigates how daily maximum temperature and…
View article: Lethal Heat and Humidity Events
Lethal Heat and Humidity Events Open
Climate change increasingly threatens global health as more frequent extreme heat events, combined with varying humidity levels, exacerbate both direct and indirect health risks, strain energy resources, and lead to economic loss. Vulnerab…
View article: Advances in the Therapy of Eosinophilic Granulomatosis with Polyangiitis (EGPA) in 2025
Advances in the Therapy of Eosinophilic Granulomatosis with Polyangiitis (EGPA) in 2025 Open
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis affecting small to medium-sized vessels, characterized by asthma, eosinophilia, and inflammation. Recent advances in the understanding of EGPA pathogenesis …
View article: Multimodal imaging analysis and structure-function correlation in patients exposed to pentosan polysulfate sodium
Multimodal imaging analysis and structure-function correlation in patients exposed to pentosan polysulfate sodium Open
Purpose: To study the anatomic and functional retinal changes in patients exposed to pentosan polysulfate (PPS) using multimodal imaging and mesopic microperimetry. Design: A cross-sectional consecutive case series. Methods: Patients expos…
View article: Perceived impact of heat stress on health and productivity of tropical female garment workers– a comparison between cool and hot months
Perceived impact of heat stress on health and productivity of tropical female garment workers– a comparison between cool and hot months Open
Background Challenging work conditions, characterized by high temperatures and humidity without the availability of adequate cooling systems, can put garment workers at an increased risk of heat stress. We examined the impact of heat stres…
View article: Perceived impact of heat stress on health and productivity of tropical female garment workers – A comparison between cool and hot months
Perceived impact of heat stress on health and productivity of tropical female garment workers – A comparison between cool and hot months Open
Background Challenging work conditions, characterized by high temperatures and humidity without the availability of adequate cooling systems, can put garment workers at an increased risk of heat stress. We examined the impact of heat stres…
View article: Exertional heat illness: international military-oriented lessons learned and best practices for prevention and management
Exertional heat illness: international military-oriented lessons learned and best practices for prevention and management Open
Climate change has resulted in more frequent and intense heat waves, leading to elevated global temperatures and posing a significant health threat to individuals working in hot environments such as military personnel. Ensuring both safety…
View article: Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability
Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability Open
Non-canonical roles for growth factors in the nucleus have been previously described, but their mechanism of action and biological roles remain enigmatic. Platelet-derived growth factor B (PDGFB) can drive formation of low-grade glioma and…
View article: Interferometric single-shot parity measurement in InAs–Al hybrid devices
Interferometric single-shot parity measurement in InAs–Al hybrid devices Open
The fusion of non-Abelian anyons is a fundamental operation in measurement-only topological quantum computation1. In one-dimensional topological superconductors (1DTSs)2-4, fusion amounts to a determination of the shared fermion parity of …
View article: Roadmap to fault tolerant quantum computation using topological qubit arrays
Roadmap to fault tolerant quantum computation using topological qubit arrays Open
We describe a concrete device roadmap towards a fault-tolerant quantum computing architecture based on noise-resilient, topologically protected Majorana-based qubits. Our roadmap encompasses four generations of devices: a single-qubit devi…
View article: Advancing heat wave definitions: a policy review towards prioritizing health impacts of extreme heat
Advancing heat wave definitions: a policy review towards prioritizing health impacts of extreme heat Open
Approaches to defining a heat wave vary globally. While they are mostly meteorology-centric, there is an increasing need to consider their health implications. Our methodology involved a review of biometeorological indices, followed by a s…
View article: Physical Work in Humid Heat Impairs Postural Balance during Simulated Construction Tasks at Height
Physical Work in Humid Heat Impairs Postural Balance during Simulated Construction Tasks at Height Open
Purpose Occupational heat strain can impair construction workers’ motor and cognitive functions, potentially leading to accidents, injuries and lowered productivity. We examined the effects of physical work under various warm and humid tro…
View article: Hexatriene cyclization in acid zeolites investigated using density functional theory methods
Hexatriene cyclization in acid zeolites investigated using density functional theory methods Open
"Aromatic compounds are an important segment of the chemical industry that impacts many aspects of everyday life. Although the majority of aromatic compounds are made from petroleum, there is renewed interest in converting shale-gas derive…
View article: Redesigning Home Reversion Products to Empower Retirement for Singapore’s Public Flat Owners
Redesigning Home Reversion Products to Empower Retirement for Singapore’s Public Flat Owners Open
This paper introduces an innovative sell-type home reversion product aimed at monetizing Singapore’s public flats, serving as a new alternative to the existing Singapore Lease Buyback Scheme (LBS). This new product not only retains the LBS…
View article: Humid heat exceeds human tolerance limits and causes mass mortality
Humid heat exceeds human tolerance limits and causes mass mortality Open
The hottest boreal summer on record has driven widespread humid heat mortality across every continent of the Northern Hemisphere. With critical physiological limits to human heat tolerance drawing ever closer, this Comment highlights the u…
View article: Measuring short-form factuality in large language models
Measuring short-form factuality in large language models Open
We present SimpleQA, a benchmark that evaluates the ability of language models to answer short, fact-seeking questions. We prioritized two properties in designing this eval. First, SimpleQA is challenging, as it is adversarially collected …
View article: 7967 Ruxolitinib Prevents Immune-Checkpoint Inhibitor-Related Diabetes Mellitus Via Inhibition Of Pathogenic IL-21 And IFNγ-Producing CD4+ T Cells
7967 Ruxolitinib Prevents Immune-Checkpoint Inhibitor-Related Diabetes Mellitus Via Inhibition Of Pathogenic IL-21 And IFNγ-Producing CD4+ T Cells Open
Disclosure: N.L. Huang: None. J. Ortega: None. S.J. Wang: None. L.N. Scott: None. K. Kimbrell: None. E. McCarthy: None. J. Olay: None. J.N. Nguyen: None. K. Kim: None. J. Lee: None. M.G. Lechner: None. The use of immune checkpoint inhibito…
View article: Gut Archaeal Abundance Is Impacted by the Intake Level of Dietary Nutrients
Gut Archaeal Abundance Is Impacted by the Intake Level of Dietary Nutrients Open
Objectives: Archaea that produce methane gas (methanogens) are the largest component of the human gut archaeome and M. smithii is believed to be the primary methanogen. There is limited fecal metagenome data examining the association betwe…