Jason Kantorow
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View article: A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
View article: Multiomic identification of genome-wide DNA binding sites and target genes identifies HIF1α as a hypoxia-dependent master regulator of lens gene expression
Multiomic identification of genome-wide DNA binding sites and target genes identifies HIF1α as a hypoxia-dependent master regulator of lens gene expression Open
View article: A Functional Map of Genomic HIF1α-DNA Complexes in The Eye Lens Revealed Through Multiomics Analysis
A Functional Map of Genomic HIF1α-DNA Complexes in The Eye Lens Revealed Through Multiomics Analysis Open
Background: During eye lens development the fetal vasculature regresses leaving the lens without a direct oxygen source. Both embryonically and throughout adult life, the lens contains a decreasing oxygen gradient from the surface to the c…
View article: Additional file 5 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
Additional file 5 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
Additional file 5: Table S5. HIF1α-regulated genes with associated mitochondria functions.
View article: Additional file 3 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
Additional file 3 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
Additional file 3 Table S3. Gene ontologies, pathways, and select literature references for differentially expressed genes with HIF1α binding.
View article: Additional file 1 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
Additional file 1 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
Additional file 1: Table S1. HIF1α binding peaks enriched by CUT&RUN and detected with MACS2 at q
View article: Additional file 2 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
Additional file 2 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
Additional file 2 Table S2. Gene expression analysis via RNA-seq of DMOG-treated vs untreated primary lens cells.
View article: Additional file 4 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
Additional file 4 of A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis Open
Additional file 4: Table S4. Enriched gene ontologies and pathways associated with HIF1α-bound upregulated and downregulated genes as determined by MsigDB and Enrichr.