Jason M. Keil
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View article: Endophthalmitis, Visual Outcomes, and Management Strategies in Eyes with Intraocular Foreign Bodies
Endophthalmitis, Visual Outcomes, and Management Strategies in Eyes with Intraocular Foreign Bodies Open
Poor presenting visual acuity and severity of injury, as measured by large wound and retinal detachment, correlate with poor visual outcome. Prompt globe closure and antimicrobial prophylaxis are critical for infection prevention. In cases…
View article: Risk Factors for Endophthalmitis Following Open Globe Injuries: A 17-Year Analysis
Risk Factors for Endophthalmitis Following Open Globe Injuries: A 17-Year Analysis Open
Prompt globe closure and subconjunctival antibiotics may reduce the risk of endophthalmitis in OGI. Furthermore, our practice of a one-time dose of systemic prophylactic antibiotics, and intravitreal antibiotics if intraocular foreign body…
View article: Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes
Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes Open
Diabetic retinopathy is one of the leading causes of vision loss and blindness. Extensive pre-clinical and clinical evidence exists for both vascular and neuronal pathology. However, the relationship of these changes in the neurovascular u…
View article: Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes
Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes Open
Diabetic retinopathy is one of the leading causes of vision loss and blindness. Extensive pre-clinical and clinical evidence exists for both vascular and neuronal pathology. However, the relationship of these changes in the neurovascular u…
View article: Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes
Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes Open
Diabetic retinopathy is one of the leading causes of vision loss and blindness. Extensive preclinical and clinical evidence exists for both vascular and neuronal pathology. However, the relationship of these changes in the neurovascular un…
View article: Symmetric Neural Progenitor Divisions Require Chromatin-Mediated Homology-Directed DNA Repair
Symmetric Neural Progenitor Divisions Require Chromatin-Mediated Homology-Directed DNA Repair Open
The cerebral cortex is generated by a highly coordinated series of cellular proliferations, beginning with symmetric neural progenitor cell (NPC) divisions to expand the pool of progenitors, and subsequent asymmetric NPC divisions that giv…
View article: Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80 Open
Chromatin regulates spatiotemporal gene expression during neurodevelopment, but it also mediates DNA damage repair essential to proliferating neural progenitor cells (NPCs). Here, we uncover molecularly dissociable roles for nucleosome rem…
View article: Nestin Selectively Facilitates the Phosphorylation of the Lissencephaly-Linked Protein Doublecortin (DCX) by cdk5/p35 to Regulate Growth Cone Morphology and Sema3a Sensitivity in Developing Neurons
Nestin Selectively Facilitates the Phosphorylation of the Lissencephaly-Linked Protein Doublecortin (DCX) by cdk5/p35 to Regulate Growth Cone Morphology and Sema3a Sensitivity in Developing Neurons Open
Nestin, an intermediate filament protein widely used as a marker of neural progenitors, was recently found to be expressed transiently in developing cortical neurons in culture and in developing mouse cortex. In young cortical cultures, ne…
View article: Endothelial expression of permeability-resistant occludin mutant preserves visual function in diabetes
Endothelial expression of permeability-resistant occludin mutant preserves visual function in diabetes Open
View article: Table of Contents
Table of Contents Open
View article: Contribution of occludin S490 phosphorylation on blood retinal barrier integrity and visual function.
Contribution of occludin S490 phosphorylation on blood retinal barrier integrity and visual function. Open
View article: Brain Transcriptome Databases: A User's Guide
Brain Transcriptome Databases: A User's Guide Open
Transcriptional programs instruct the generation and maintenance of diverse subtypes of neural cells, establishment of distinct brain regions, formation and function of neural circuits, and ultimately behavior. Spatiotemporal and cell type…