Jason Q. Core
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View article: Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19
Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19 Open
Respiratory infections are characterized by an increased risk of thrombosis, likely involving platelet-leukocyte crosstalk via pattern recognition receptors (PRRs). Here we characterized COVID19-mediated changes in PRR levels and their ass…
View article: Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations
Age of heart disease presentation and dysmorphic nuclei in patients with LMNA mutations Open
Nuclear shape defects are a distinguishing characteristic in laminopathies, cancers, and other pathologies. Correlating these defects to the symptoms, mechanisms, and progression of disease requires unbiased, quantitative, and high-through…
View article: Multiscale Characterization of Engineered Cardiac Tissue Architecture
Multiscale Characterization of Engineered Cardiac Tissue Architecture Open
In a properly contracting cardiac muscle, many different subcellular structures are organized into an intricate architecture. While it has been observed that this organization is altered in pathological conditions, the relationship between…