Jason Bingham
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View article: A Surgeon's Guide to Machine Learning.
A Surgeon's Guide to Machine Learning. Open
Machine learning (ML) represents a collection of advanced data modeling techniques beyond the traditional statistical models and tests with which most clinicians are familiar. While a subset of artificial intelligence, ML is far from the s…
View article: Hypothermia and the Global War on Terror: 18 Years of Minimal Progress
Hypothermia and the Global War on Terror: 18 Years of Minimal Progress Open
INTRODUCTION: The association between hypothermia, coagulopathy, and acidosis in trauma is well described. Hypothermia mitigation starts in the prehospital setting; however, it is often a secondary focus after other life-saving interventio…
View article: Quantifying the benefit of whole blood on mortality in trauma patients requiring emergent laparotomy.
Quantifying the benefit of whole blood on mortality in trauma patients requiring emergent laparotomy. Open
BACKGROUND: Whole blood (WB) transfusions in trauma represent an increasingly utilized resuscitation strategy in trauma patients. Previous reports suggest a probable mortality benefit with incorporating WB into massive transfusion protocol…
View article: Quantifying the benefit of whole blood on mortality in trauma patients requiring emergent laparotomy
Quantifying the benefit of whole blood on mortality in trauma patients requiring emergent laparotomy Open
BACKGROUND Whole blood (WB) transfusions in trauma represent an increasingly utilized resuscitation strategy in trauma patients. Previous reports suggest a probable mortality benefit with incorporating WB into massive transfusion protocols…
View article: Hypothermia and the Global War on Terror: 18 Years of Minimal Progress
Hypothermia and the Global War on Terror: 18 Years of Minimal Progress Open
Introduction The association between hypothermia, coagulopathy, and acidosis in trauma is well described. Hypothermia mitigation starts in the prehospital setting; however, it is often a secondary focus after other life-saving intervention…
View article: Effects of Gynecomastia Surgery on Readiness and Return to Duty in an Active Duty Military Population
Effects of Gynecomastia Surgery on Readiness and Return to Duty in an Active Duty Military Population Open
Introduction Simple mastectomies are routinely performed in the military health care system as gynecomastia can cause significant pain and discomfort when wearing body armor. Postoperative recovery negatively impacts personnel readiness. I…
View article: Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production
Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production Open
Recombinant engineering for protein production commonly employs plasmid-based gene templates for introduction and expression of genes in a candidate cell system in vitro. Challenges to this approach include identifying cell types that can …
View article: Mesenchymal stem cell therapy to promote functional recovery in a limb transplant model
Mesenchymal stem cell therapy to promote functional recovery in a limb transplant model Open
Introduction Battlefield trauma leads to limb amputations. We investigated whether Mesenchymal Stem Cell (MSC) therapy can improve nerve regeneration and functional outcome in limb transplantation (Tx). Methods We performed orthotopic syng…
View article: Bioadhesive patch as a parenchymal sparing treatment of acute traumatic pulmonary air leaks
Bioadhesive patch as a parenchymal sparing treatment of acute traumatic pulmonary air leaks Open
INTRODUCTION Traumatic pulmonary injuries are common in chest trauma. Persistent air leaks occur in up to 46% of patients depending on injury severity. Prolonged leaks are associated with increased morbidity and cost. Prior work from our f…
View article: Airborne! <scp>UAV</scp> delivery of blood products and medical logistics for combat zones
Airborne! <span>UAV</span> delivery of blood products and medical logistics for combat zones Open
Background Innovative solutions to resupply critical medical logistics and blood products may be required in future near‐peer conflicts. Unmanned aerial vehicles (UAVs) are increasingly being used in austere environments and may be a viabl…
View article: Pectin based biologic Velcro effectively seals traumatic solid organ and small bowel injuries
Pectin based biologic Velcro effectively seals traumatic solid organ and small bowel injuries Open
INTRODUCTION Injuries to the liver and small bowel are common in multiple injuries. While there are currently a variety of accepted damage-control techniques to expeditiously manage such injuries, morbidity and mortality remain high. Pecti…
View article: Surgical Training for a Disaster: Preparation of Surgical Trainees for Victims of Conflict
Surgical Training for a Disaster: Preparation of Surgical Trainees for Victims of Conflict Open
Introduction With increasing global unrest and military physician shortages potentially leading to a surgeon draft, we sought to evaluate the readiness of graduating general surgery residents to care for casualties of war. Materials and Me…
View article: Utilization of Machine Learning Approaches to Predict Mortality in Pediatric Warzone Casualties
Utilization of Machine Learning Approaches to Predict Mortality in Pediatric Warzone Casualties Open
Background Identification of pediatric trauma patients at the highest risk for death may promote optimization of care. This becomes increasingly important in austere settings with constrained medical capabilities. This study aimed to devel…
View article: Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production
Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production Open
Current hemostatic agents are obtained from pooled plasma from multiple donors requiring costly pathogen screening and processing. Recombinant DNA-based production represents an engineering solution that could improve supply, uniformity, a…
View article: A Surgeon’s Guide to Machine Learning
A Surgeon’s Guide to Machine Learning Open
Machine learning (ML) represents a collection of advanced data modeling techniques beyond the traditional statistical models and tests with which most clinicians are familiar. While a subset of artificial intelligence, ML is far from the s…
View article: Publication Productivity and Bibliometric Profiling of Graduating General Surgery Chief Residents
Publication Productivity and Bibliometric Profiling of Graduating General Surgery Chief Residents Open
This cross-sectional study assesses the publication productivity of graduating general surgery residents as well as factors associated with a chief resident’s academic research output.