Jason Yap
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View article: Challenges in managing cervical cancer in pregnancy: Three case reports
Challenges in managing cervical cancer in pregnancy: Three case reports Open
Cervical cancer in pregnancy is a rare but increasingly recognised condition, affecting approximately 0.1–12.0 per 10,000 pregnancies annually. Symptoms such as vaginal bleeding, discharge, dyspareunia, and pelvic pain may overlap with nor…
View article: Single cell functional immunogenomics of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention
Single cell functional immunogenomics of the fallopian tube reveals a precursor immune surveillance network for ovarian cancer prevention Open
The fallopian tube (FT) is increasingly recognized as the site of origin for high-grade serous ovarian cancer (HGSOC), yet its immune landscape and potential role in tumor surveillance remain poorly understood. Here, we employ single-cell …
View article: A Comprehensive Study on the Modern Approaches to the Instrumental and Laboratory Diagnostics of Chronic Obstructive Pulmonary Disease in the Practice of GPs from the point of view of Evidence-based Medicine
A Comprehensive Study on the Modern Approaches to the Instrumental and Laboratory Diagnostics of Chronic Obstructive Pulmonary Disease in the Practice of GPs from the point of view of Evidence-based Medicine Open
Background: Chronic Obstructive Pulmonary Disease (COPD) is a progressive, life-limiting respiratory condition and a leading cause of global morbidity and mortality. Despite advances in treatment, underdiagnosis and misdiagnosis remain pre…
View article: Femoral vein ligation for groin recurrence in a woman with vulval squamous cell carcinoma: A case report
Femoral vein ligation for groin recurrence in a woman with vulval squamous cell carcinoma: A case report Open
The management of groin recurrences in women with vulval cancer presents a significant therapeutic challenge. Groin recurrences, particularly those involving the femoral vessels, are associated with poor outcomes. Historically, surgery was…
View article: History of intestinal transplantation in Australia
History of intestinal transplantation in Australia Open
Intestinal transplantation was introduced into Australia in 2010 to meet the need of a small number of patients with irreversible intestinal failure who would otherwise need to travel abroad to access this life-saving therapy. Due to small…
View article: Developing a platform to investigate the heterogeneity of outcomes for patients with ovarian cancer
Developing a platform to investigate the heterogeneity of outcomes for patients with ovarian cancer Open
Background The geographical variation in treatment patterns for patients with ovarian cancer is profound, long-standing and worrying. Although these variations were highlighted in a recent UK registry audit, granular data to provide explan…
View article: A study of professional practices, attitudes and barriers to blended tube feeding in <scp>Australia</scp> and <scp>New Zealand</scp>
A study of professional practices, attitudes and barriers to blended tube feeding in <span>Australia</span> and <span>New Zealand</span> Open
Aims This study investigates the utilisation of blended tube feeding by health professionals in Australia and New Zealand, assessing factors influencing its implementation following the Australasian Society of Parenteral and Enteral Nutrit…
View article: The chromatin landscape of high-grade serous ovarian cancer metastasis identifies regulatory drivers in post-chemotherapy residual tumour cells
The chromatin landscape of high-grade serous ovarian cancer metastasis identifies regulatory drivers in post-chemotherapy residual tumour cells Open
View article: Investigating age and ethnicity as novel high-risk phenotypes in mucinous ovarian cancer: retrospective study in a multi-ethnic population
Investigating age and ethnicity as novel high-risk phenotypes in mucinous ovarian cancer: retrospective study in a multi-ethnic population Open
View article: Sentinel Lymph Node Biopsy Based on Anatomical Landmarks and Locoregional Mapping of Inguinofemoral Sentinel Lymph Nodes in Women with Vulval Cancer: an Operative Technique.
Sentinel Lymph Node Biopsy Based on Anatomical Landmarks and Locoregional Mapping of Inguinofemoral Sentinel Lymph Nodes in Women with Vulval Cancer: an Operative Technique. Open
Inguinal lymph node involvement is the most robust predictor of mortality in women with vulval cancer and sentinel lymph node biopsy is recognised as a safe diagnostic modality provided strict patient criteria as defined by the GROINSS-V s…
View article: Comparison of Body Composition, Muscle Strength and Cardiometabolic Profile in Children with Prader-Willi Syndrome and Non-Alcoholic Fatty Liver Disease: A Pilot Study
Comparison of Body Composition, Muscle Strength and Cardiometabolic Profile in Children with Prader-Willi Syndrome and Non-Alcoholic Fatty Liver Disease: A Pilot Study Open
Syndromic and non-syndromic obesity conditions in children, such as Prader-Willi syndrome (PWS) and non-alcoholic fatty liver disease (NAFLD), both lower quality of life and increase risk for chronic health complications, which further inc…
View article: 2022-RA-619-ESGO Less is more? Simple hysterectomy versus radical hysterectomy in FIGO 2018 stage IA2 cervical carcinoma: a pan-birmingham gynaecological cancer centre population-based longitudinal cohort study
2022-RA-619-ESGO Less is more? Simple hysterectomy versus radical hysterectomy in FIGO 2018 stage IA2 cervical carcinoma: a pan-birmingham gynaecological cancer centre population-based longitudinal cohort study Open
View article: 2022-RA-893-ESGO Is ethnicity a risk factor for differential outcomes in mucinous ovarian cancer? experience from a UK gynaecological oncology centre
2022-RA-893-ESGO Is ethnicity a risk factor for differential outcomes in mucinous ovarian cancer? experience from a UK gynaecological oncology centre Open
View article: 2022-RA-620-ESGO Querleu-Morrow type A hysterectomy for low-risk early-stage (FIGO 2018 IA2-IB1) cervical cancer: a UK population-based retrospective cohort study
2022-RA-620-ESGO Querleu-Morrow type A hysterectomy for low-risk early-stage (FIGO 2018 IA2-IB1) cervical cancer: a UK population-based retrospective cohort study Open
View article: Australasian paediatric gastroenterologist practices of coeliac disease diagnosis before and during the COVID‐19 pandemic
Australasian paediatric gastroenterologist practices of coeliac disease diagnosis before and during the COVID‐19 pandemic Open
Aim To explore the perceptions and practices of Australasian paediatric gastroenterologists in diagnosing coeliac disease (CD) before and during the COVID‐19 pandemic. Methods Paediatric gastroenterologists in Australasia were invited via …
View article: An international multicenter validation study of the Toronto listing criteria for pediatric intestinal transplantation
An international multicenter validation study of the Toronto listing criteria for pediatric intestinal transplantation Open
View article: The Effect of the COVID-19 Pandemic in Intestinal Rehabilitation and Transplant Patients: Initial Results of the Intestinal Rehabilitation and Transplant Association’s International Survey
The Effect of the COVID-19 Pandemic in Intestinal Rehabilitation and Transplant Patients: Initial Results of the Intestinal Rehabilitation and Transplant Association’s International Survey Open
INTRODUCTION The World Health Organization declared the coronavirus disease 2019 (COVID-19) outbreak as a global public health emergency on January 30, 2020, and as a pandemic on March 11th of the same year. Worldwide, health systems had t…
View article: Non-invasive test of liver fibrosis for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Non-invasive test of liver fibrosis for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: Magnetic resonance imaging, computer tomography scan, and oesophagography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Magnetic resonance imaging, computer tomography scan, and oesophagography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: Transient ultrasound elastography and magnetic resonance elastography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Transient ultrasound elastography and magnetic resonance elastography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis Open
This protocol for a Cochrane Review is out of date. The authors have abandoned it.
View article: Pre‐school neurocognitive and functional outcomes after liver transplant in children with early onset urea cycle disorders, maple syrup urine disease, and propionic acidemia: An inception cohort matched‐comparison study
Pre‐school neurocognitive and functional outcomes after liver transplant in children with early onset urea cycle disorders, maple syrup urine disease, and propionic acidemia: An inception cohort matched‐comparison study Open
Background Urea cycle disorders (UCD) and organic acid disorders classically present in the neonatal period. In those who survive, developmental delay is common with continued risk of regression. Liver transplantation improves the biochemi…
View article: Indications and Patterns of Use for Parenteral Nutrition in Pediatric Oncology
Indications and Patterns of Use for Parenteral Nutrition in Pediatric Oncology Open
Background Children with cancer are at risk of treatment related gastrointestinal toxicity and malnutrition. Intestinal dysfunction may preclude or limit use of enteral nutrition, and parenteral nutrition (PN) may be required. Published in…
View article: Bacille Calmette-Guerin (BCG) vaccine for induction of remission in Crohn's disease
Bacille Calmette-Guerin (BCG) vaccine for induction of remission in Crohn's disease Open
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective is to systematically assess the efficacy and safety of BCG vaccine for induction of remission in active Crohn's disease.
View article: Duodenal Bulb Histology in Paediatric Celiac Disease: A Case–Control Study
Duodenal Bulb Histology in Paediatric Celiac Disease: A Case–Control Study Open
Background Controversy exists about optimal methods for duodenal biopsy in diagnosis of celiac disease (CD), in terms of both number of samples and anatomic location. The reliability of duodenal bulb biopsy has been questioned given that n…
View article: Gamma Glutamyltransferase Reduction Is Associated With Favorable Outcomes in Pediatric Primary Sclerosing Cholangitis
Gamma Glutamyltransferase Reduction Is Associated With Favorable Outcomes in Pediatric Primary Sclerosing Cholangitis Open
Adverse clinical events in primary sclerosing cholangitis (PSC) happen too slowly to capture during clinical trials. Surrogate endpoints are needed, but no such validated endpoints exist for children with PSC. We evaluated the association …
View article: KINDERGARTEN-AGE NEUROCOGNITIVE AND FUNCTIONAL OUTCOMES AFTER LIVER TRANSPLANTATION DONE AT AGE <6 YEARS
KINDERGARTEN-AGE NEUROCOGNITIVE AND FUNCTIONAL OUTCOMES AFTER LIVER TRANSPLANTATION DONE AT AGE <6 YEARS Open
BACKGROUND Mortality after liver transplant has improved, making long-term outcomes increasingly important. OBJECTIVES To describe neurocognitive and functional outcomes after liver transplant done in young children, and determine potentia…
View article: KINDERGARTEN-AGE QUALITY OF LIFE OUTCOMES AFTER LIVER TRANSPLANTATION AT <6 YEARS
KINDERGARTEN-AGE QUALITY OF LIFE OUTCOMES AFTER LIVER TRANSPLANTATION AT <6 YEARS Open
BACKGROUND Given the improved mortality after paediatric liver transplantation, health related quality of life (HRQL) is an important outcome measure and provides valuable information for families. OBJECTIVES To determine the HRQL of kinde…
View article: A309 EFFECT OF MIXED LIPID, ω-3 FISH OIL AND ω-6 SOYBEAN OIL PARENTERAL LIPID EMULSIONS ON LIVER DISEASE, HEPATIC LIPID AND PHYTOSTEROL COMPOSITION IN NEONATAL PIGLETS.
A309 EFFECT OF MIXED LIPID, ω-3 FISH OIL AND ω-6 SOYBEAN OIL PARENTERAL LIPID EMULSIONS ON LIVER DISEASE, HEPATIC LIPID AND PHYTOSTEROL COMPOSITION IN NEONATAL PIGLETS. Open
BACKGROUND: Determining the optimal lipid emulsion in parenteral nutrition (PN) for pediatric intestinal failure (PIF) patients remains an important clinical question given the risk of PN associated liver disease (PNALD). AIMS: Using a neo…
View article: Bacillus Calmette Guerin (BCG) Vaccine for Inducing and Maintaining Remission in Crohn's Disease: A Systematic Review
Bacillus Calmette Guerin (BCG) Vaccine for Inducing and Maintaining Remission in Crohn's Disease: A Systematic Review Open
Objectives: Bacillus Calmette Guerin (BCG) vaccine may act as an immune stimulant. The aim of this review was to systematically assess the efficacy and safety of BCG vaccine for induction and maintenance of remission in CD. Methods: A syst…
View article: Platelet count, spleen length, and platelet count-to-spleen length ratio for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis
Platelet count, spleen length, and platelet count-to-spleen length ratio for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis Open
Platelet count-to-spleen length ratio could be used to stratify the risk of oesophageal varices. This test can be used as a triage test before endoscopy, thus ruling out adults without varices. In the case of a ratio > 909 (n/mm3