Jason Yuen
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View article: Micromagnetic Stimulation (μMS) Controls Dopamine Release: An in vivo Study Using WINCS Harmoni
Micromagnetic Stimulation (μMS) Controls Dopamine Release: An in vivo Study Using WINCS Harmoni Open
Research into the role of neurotransmitters in regulating normal and pathologic brain functions has made significant progress. Yet, clinical trials that aim to improve therapeutic interventions do not take advantage of the in vivo changes …
View article: A Multimodal Platform for Real-Time Neurochemical and Electrophysiologic Monitoring for Intraoperative Neurosurgical Applications
A Multimodal Platform for Real-Time Neurochemical and Electrophysiologic Monitoring for Intraoperative Neurosurgical Applications Open
View article: Expansion of stereotactic work envelope using transformation matrices and geometric algebra for neurosurgery
Expansion of stereotactic work envelope using transformation matrices and geometric algebra for neurosurgery Open
View article: Resolution of tonic concentrations of highly similar neurotransmitters using voltammetry and deep learning
Resolution of tonic concentrations of highly similar neurotransmitters using voltammetry and deep learning Open
View article: Improved circuitry and post-processing for interleaved fast-scan cyclic voltammetry and electrophysiology measurements
Improved circuitry and post-processing for interleaved fast-scan cyclic voltammetry and electrophysiology measurements Open
The combination of electrophysiology and electrochemistry acquisition methods using a single carbon fiber microelectrode (CFM) in the brain has enabled more extensive analysis of neurochemical release, neural activity, and animal behavior.…
View article: Oxycodone-induced dopaminergic and respiratory effects are modulated by deep brain stimulation
Oxycodone-induced dopaminergic and respiratory effects are modulated by deep brain stimulation Open
Introduction: Opioids are the leading cause of overdose death in the United States, accounting for almost 70,000 deaths in 2020. Deep brain stimulation (DBS) is a promising new treatment for substance use disorders. Here, we hypothesized t…
View article: Micromagnetic Stimulation (μMS) Controls Dopamine Release: An<i>in vivo</i>Study Using WINCS<i>Harmoni</i>
Micromagnetic Stimulation (μMS) Controls Dopamine Release: An<i>in vivo</i>Study Using WINCS<i>Harmoni</i> Open
Objective Research into the role of neurotransmitters in regulating normal and pathologic brain functions has made significant progress. Yet, clinical trials that aim to improve therapeutic interventions do not take advantage of the in viv…
View article: Deep brain stimulation alleviates tics in Tourette syndrome via striatal dopamine transmission
Deep brain stimulation alleviates tics in Tourette syndrome via striatal dopamine transmission Open
Tourette syndrome is a childhood-onset neuropsychiatric disorder characterized by intrusive motor and vocal tics that can lead to self-injury and deleterious mental health complications. While dysfunction in striatal dopamine neurotransmis…
View article: Treating addiction with deep brain stimulation: Ethical and legal considerations
Treating addiction with deep brain stimulation: Ethical and legal considerations Open
View article: High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens
High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens Open
Cocaine’s addictive properties stem from its capacity to increase tonic extracellular dopamine levels in the nucleus accumbens (NAc). The ventral tegmental area (VTA) is a principal source of NAc dopamine. To investigate how high frequency…
View article: Deep Brain Stimulator Device Infection: The Mayo Clinic Rochester Experience
Deep Brain Stimulator Device Infection: The Mayo Clinic Rochester Experience Open
Background Deep brain stimulator (DBS)–related infection is a recognized complication that may significantly alter the course of DBS therapy. We describe the Mayo Clinic Rochester experience with DBS-related infections. Methods This was a …
View article: Comparison of the impact of skull density ratio with alternative skull metrics on magnetic resonance–guided focused ultrasound thalamotomy for tremor
Comparison of the impact of skull density ratio with alternative skull metrics on magnetic resonance–guided focused ultrasound thalamotomy for tremor Open
OBJECTIVE One of the key metrics that is used to predict the likelihood of success of MR-guided focused ultrasound (MRgFUS) thalamotomy is the overall calvarial skull density ratio (SDR). However, this measure does not fully predict the so…
View article: Bibliometric Trends in Open Surgical and Endovascular Cerebrovascular Research
Bibliometric Trends in Open Surgical and Endovascular Cerebrovascular Research Open
The last decade has witnessed a major expansion in endovascular interventions concurrent with a contraction of open neurovascular surgeries. Whether research efforts have also shifted from open to endovascular neurosurgery is an effect tha…
View article: Deep Brain Stimulation for Addictive Disorders—Where Are We Now?
Deep Brain Stimulation for Addictive Disorders—Where Are We Now? Open
In the face of a global epidemic of drug addiction, neglecting to develop new effective therapies will perpetuate the staggering human and economic costs of substance use. This review aims to summarize and evaluate the preclinical and clin…
View article: Spinal Aneurysmal Bone Cyst Causing Spinal Cord Compression
Spinal Aneurysmal Bone Cyst Causing Spinal Cord Compression Open
View article: Table of Contents
Table of Contents Open
View article: Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens
Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens Open
Serotonin plays a vital role in drug addiction. Here, using N-shaped fast-scan cyclic voltammetry, we demonstrated the effect of cocaine on the phasic release of serotonin at the nucleus accumbens core. To the best of our knowledge, this h…
View article: Referee report. For: The perceived impact of the COVID-19 pandemic on medical students’ future careers [version 1; peer review: 1 approved with reservations]
Referee report. For: The perceived impact of the COVID-19 pandemic on medical students’ future careers [version 1; peer review: 1 approved with reservations] Open
View article: Hyperostosis in Combination With Low Skull Density Ratio: A Potential Contraindication for Magnetic Resonance Imaging–Guided Focused Ultrasound Thalamotomy
Hyperostosis in Combination With Low Skull Density Ratio: A Potential Contraindication for Magnetic Resonance Imaging–Guided Focused Ultrasound Thalamotomy Open
View article: Tonic Serotonin Measurements<i>In Vivo</i>Using N-Shaped Multiple Cyclic Square Wave Voltammetry
Tonic Serotonin Measurements<i>In Vivo</i>Using N-Shaped Multiple Cyclic Square Wave Voltammetry Open
Here, we present the development of a novel voltammetric technique, N-shaped multiple cyclic square wave voltammetry (N-MCSWV) and its application in vivo. It allows quantitative measurements of tonic extracellular levels of seroton…
View article: Cocaine-Induced Changes in Tonic Dopamine Concentrations Measured Using Multiple-Cyclic Square Wave Voltammetry in vivo
Cocaine-Induced Changes in Tonic Dopamine Concentrations Measured Using Multiple-Cyclic Square Wave Voltammetry in vivo Open
For over 40 years, in vivo microdialysis techniques have been at the forefront in measuring the effects of illicit substances on brain tonic extracellular levels of dopamine that underlie many aspects of drug addiction. However, the size o…
View article: Biomarkers for Deep Brain Stimulation in Animal Models of Depression
Biomarkers for Deep Brain Stimulation in Animal Models of Depression Open
View article: Automatic and Reliable Quantification of Tonic Dopamine Concentrations <i>In Vivo</i> Using a Novel Probabilistic Inference Method
Automatic and Reliable Quantification of Tonic Dopamine Concentrations <i>In Vivo</i> Using a Novel Probabilistic Inference Method Open
Dysregulation of the neurotransmitter dopamine (DA) is implicated in several neuropsychiatric conditions. Multiple-cyclic square-wave voltammetry (MCSWV) is a state-of-the-art technique for measuring tonic DA levels with high sensitivity (…
View article: What Is the Role of 3D Printing in Undergraduate Anatomy Education? A Scoping Review of Current Literature and Recommendations
What Is the Role of 3D Printing in Undergraduate Anatomy Education? A Scoping Review of Current Literature and Recommendations Open
View article: Medical education during the COVID-19 pandemic: perspectives from UK trainees
Medical education during the COVID-19 pandemic: perspectives from UK trainees Open
This article is freely available via Open Access. Click on the Publisher URL to access it via the publisher's site.
View article: Reverse Wilson’s framing for lumbar spinal surgery in patients with stiff shoulders
Reverse Wilson’s framing for lumbar spinal surgery in patients with stiff shoulders Open
View article: Usefulness of antero-posterior radiograph and variability of management in non-major thoracolumbar injuries: a single centre pilot study and review of literature
Usefulness of antero-posterior radiograph and variability of management in non-major thoracolumbar injuries: a single centre pilot study and review of literature Open
View article: 2018 National Big Data Challenge for High School Students: Think Global Act Local with Big Data
2018 National Big Data Challenge for High School Students: Think Global Act Local with Big Data Open
The goal of this paper is to determine whether there is a correlation between awareness of global warming, and where global warming occurs.This theory is carried out by analyzing maps containing various forms of data that have to do with g…
View article: Complication rates of external ventricular drain insertion by surgeons of different experience
Complication rates of external ventricular drain insertion by surgeons of different experience Open
Introduction Insertion of external ventricular drain (EVD) is a widely accepted, routinely performed procedure for treatment of hydrocephalus and raised intracranial pressure. The purpose of this study was to investigate whether a surgeon’…
View article: A Case of Invasive Sinonasal Carcinosarcoma: The Importance of Early Detection
A Case of Invasive Sinonasal Carcinosarcoma: The Importance of Early Detection Open
Sinonasal carcinosarcomas represent rare neoplasms, with aggressive character and unfavourable prognosis. We present a case of extensive sinonasal carcinosarcoma extending into the anterior cranial fossa and into the orbit and also a revie…