Jasper K W Gerritsen
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View article: OS08.7.A NEUROSURGEONS’ VIEWS ON SURGICAL TRIALS FOR GLIOBLASTOMA: ATTITUDES, PRACTICES, AND WILLINGNESS TO RANDOMIZE
OS08.7.A NEUROSURGEONS’ VIEWS ON SURGICAL TRIALS FOR GLIOBLASTOMA: ATTITUDES, PRACTICES, AND WILLINGNESS TO RANDOMIZE Open
BACKGROUND The scarcity of randomized controlled trials (RCTs) in surgical neuro-oncology tends to limit the level of evidence for clinical practice. Specifically in the surgical treatment of glioblastoma, controversies on the optimal oper…
View article: OS11.6.A A COMPREHENSIVE FRAMEWORK FOR INTRAOPERATIVE MAPPING AND MONITORING, AND PERIOPERATIVE NEUROLOGICAL, LINGUISTIC, AND OUTCOME ASSESSMENT IN GLIOMA RESECTION: CONSENSUS RECOMMENDATIONS FROM THE PIONEER CONSORTIUM AND RANO RESECT GROUP
OS11.6.A A COMPREHENSIVE FRAMEWORK FOR INTRAOPERATIVE MAPPING AND MONITORING, AND PERIOPERATIVE NEUROLOGICAL, LINGUISTIC, AND OUTCOME ASSESSMENT IN GLIOMA RESECTION: CONSENSUS RECOMMENDATIONS FROM THE PIONEER CONSORTIUM AND RANO RESECT GROUP Open
BACKGROUND In adult patients with diffuse glioma, greater extent of resection is associated with longer overall and progression-free survival. Intraoperative mapping and monitoring techniques are essential to safely achieve maximum resecti…
View article: P12.62.A SECOND SURGERY FOR RECURRENT GLIOBLASTOMA: DOES IT PROLONG SURVIVAL? A PROPENSITY SCORED MATCHED ANALYSIS
P12.62.A SECOND SURGERY FOR RECURRENT GLIOBLASTOMA: DOES IT PROLONG SURVIVAL? A PROPENSITY SCORED MATCHED ANALYSIS Open
BACKGROUND Glioblastoma is the most aggressive primary brain tumor in adults, comprising 49% of malignant brain tumors. Standard treatment includes surgical resection, radiation, and chemotherapy, yet prognosis remains poor with a median o…
View article: OS11.5.A PREOPERATIVE ASSESSMENT OF TUMOR ELOQUENCE AND RESECTABILITY: AN INTERNATIONAL SURVEY
OS11.5.A PREOPERATIVE ASSESSMENT OF TUMOR ELOQUENCE AND RESECTABILITY: AN INTERNATIONAL SURVEY Open
BACKGROUND Tumor location and its proximity to eloquent brain areas are key factors in glioma surgery decision-making. However, the absence of a consensus definition for eloquent brain areas leads to variability in surgical decision-making…
View article: P06.03.A SEMI-SPONTANEOUS SPEECH WITH ORAL PICTURE DESCRIPTION IN GLIOBLASTOMA PATIENTS BEFORE AND AFTER AWAKE TUMOUR RESECTION
P06.03.A SEMI-SPONTANEOUS SPEECH WITH ORAL PICTURE DESCRIPTION IN GLIOBLASTOMA PATIENTS BEFORE AND AFTER AWAKE TUMOUR RESECTION Open
BACKGROUND Spontaneous speech analysis is a reliable method to detect language problems in neurological populations. Deviations in spontaneous speech of glioma patients consist of incomplete sentences, shorter mean length of utterance (MLU…
View article: Correction to: Preoperative assessment of tumor eloquence and resectability: an international survey
Correction to: Preoperative assessment of tumor eloquence and resectability: an international survey Open
View article: P.143 Eligibility criteria in glioma clinical trials: a systematic review and meta-analysis on selectivity, generalizability, and real-world applicability
P.143 Eligibility criteria in glioma clinical trials: a systematic review and meta-analysis on selectivity, generalizability, and real-world applicability Open
Background: Glioma trials may use selective criteria, limiting their generalizability to real-world patients. This systematic review and meta-analysis quantifies the prevalence of these criteria and evaluates their impact on trial outcomes…
View article: Preoperative assessment of tumor eloquence and resectability: an international survey
Preoperative assessment of tumor eloquence and resectability: an international survey Open
View article: Simulation tools in neuro-oncological surgery: a scoping review of perioperative and training applications
Simulation tools in neuro-oncological surgery: a scoping review of perioperative and training applications Open
Background Neuro-oncological surgery has lagged other neurosurgical subspecialties in integrating simulation technologies for training and surgical planning. This study provides a comprehensive scoping review of the current landscape of si…
View article: Practical and statistical aspects of subgroup analyses in surgical neuro-oncology: A comprehensive review from the PIONEER consortium
Practical and statistical aspects of subgroup analyses in surgical neuro-oncology: A comprehensive review from the PIONEER consortium Open
Subgroup analyses are essential to generate new hypotheses or to estimate treatment effects in clinically meaningful subgroups of patients. They play an important role in taking the next step toward personalized surgical treatment for brai…
View article: The impact of intraoperative mapping during re-resection in recurrent gliomas: a systematic review
The impact of intraoperative mapping during re-resection in recurrent gliomas: a systematic review Open
View article: Development and validation of a clinical risk model for postoperative outcome in newly diagnosed glioblastoma: A report of the RANO <i>resect</i> group
Development and validation of a clinical risk model for postoperative outcome in newly diagnosed glioblastoma: A report of the RANO <i>resect</i> group Open
Background Following surgery, patients with newly diagnosed glioblastoma frequently enter clinical trials. Nuanced risk assessment is warranted to reduce imbalances between study arms. Here, we aimed (I) to analyze the interactive effects …
View article: Onco-functional outcome after resection for eloquent glioblastoma (OFO): A propensity-score matched analysis of an international, multicentre, cohort study
Onco-functional outcome after resection for eloquent glioblastoma (OFO): A propensity-score matched analysis of an international, multicentre, cohort study Open
OFO1 was associated with improved OS, PFS, and receipt of adjuvant therapy in all glioblastoma patients with IDH-wildtype and MGMT-methylated tumors. Awake craniotomy was associated with achieving this optimal OFO status. Preventing defici…
View article: Resection versus biopsy in patients with glioblastoma (RESBIOP study): study protocol for an international multicentre prospective cohort study (ENCRAM 2202)
Resection versus biopsy in patients with glioblastoma (RESBIOP study): study protocol for an international multicentre prospective cohort study (ENCRAM 2202) Open
Introduction There are no guidelines or prospective studies defining the optimal surgical treatment for glioblastomas in older patients (≥70 years), for those with a limited functioning performance at presentation (Karnofsky Performance Sc…
View article: SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201)
SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201) Open
Introduction A greater extent of resection of the contrast-enhancing (CE) tumour part has been associated with improved outcomes in glioblastoma. Recent results suggest that resection of the non-contrast-enhancing (NCE) part might yield ev…
View article: Level I and II deficits—A clinical survey on international practice of awake craniotomy and definitions of postoperative “major” and “minor” deficits
Level I and II deficits—A clinical survey on international practice of awake craniotomy and definitions of postoperative “major” and “minor” deficits Open
Background Awake craniotomy (AC) is a technique that balances maximum resection and minimal postoperative deficits in patients with intracranial tumors. To aid in the comparability of functional outcomes after awake surgery, this study inv…
View article: P11.83.B ONCO-FUNCTIONAL OUTCOME (OFO) AFTER RESECTION FOR ELOQUENT GLIOBLASTOMA (GLIOFO STUDY): A PROPENSITY-SCORED ANALYSIS OF AN INTERNATIONAL, MULTICENTER COHORT STUDY
P11.83.B ONCO-FUNCTIONAL OUTCOME (OFO) AFTER RESECTION FOR ELOQUENT GLIOBLASTOMA (GLIOFO STUDY): A PROPENSITY-SCORED ANALYSIS OF AN INTERNATIONAL, MULTICENTER COHORT STUDY Open
BACKGROUND Minimizing residual tumor volume and preventing functional loss are the primary goal in glioblastoma resections in eloquent areas. However, their combined impact on patient outcomes remains poorly understood. We therefore develo…
View article: P11.04.B ASSESSMENT OF TUMOR ELOQUENCE IN GLIOMA RESECTIONS: A SYSTEMATIC REVIEW
P11.04.B ASSESSMENT OF TUMOR ELOQUENCE IN GLIOMA RESECTIONS: A SYSTEMATIC REVIEW Open
BACKGROUND Tumor location and eloquence are two crucial factors when deciding on the optimal surgical strategy in glioma management. Consensus is currently lacking on the assessment and definition of eloquent areas. This systematic review …
View article: Impact of dedicated neuro-anesthesia management on clinical outcomes in glioblastoma patients: A single-institution cohort study
Impact of dedicated neuro-anesthesia management on clinical outcomes in glioblastoma patients: A single-institution cohort study Open
Background Glioblastomas are mostly resected under general anesthesia under the supervision of a general anesthesiologist. Currently, it is largely unkown if clinical outcomes of GBM patients can be improved by appointing a neuro-anesthesi…
View article: Impact of maximal extent of resection on postoperative deficits, patient functioning, and survival within clinically important glioblastoma subgroups
Impact of maximal extent of resection on postoperative deficits, patient functioning, and survival within clinically important glioblastoma subgroups Open
Background The impact of extent of resection (EOR), residual tumor volume (RTV), and gross-total resection (GTR) in glioblastoma subgroups is currently unknown. This study aimed to analyze their impact on patient subgroups in relation to n…
View article: Safe surgery for glioblastoma: Recent advances and modern challenges
Safe surgery for glioblastoma: Recent advances and modern challenges Open
One of the major challenges during glioblastoma surgery is balancing between maximizing extent of resection and preventing neurological deficits. Several surgical techniques and adjuncts have been developed to help identify eloquent areas …
View article: Global comparison of awake and asleep mapping procedures in glioma surgery: An international multicenter survey
Global comparison of awake and asleep mapping procedures in glioma surgery: An international multicenter survey Open
Background Mapping techniques are frequently used to preserve neurological function during glioma surgery. There is, however, no consensus regarding the use of many variables of these techniques. Currently, there are almost no objective da…
View article: The PROGRAM study: awake mapping versus asleep mapping versus no mapping for high-grade glioma resections: study protocol for an international multicenter prospective three-arm cohort study
The PROGRAM study: awake mapping versus asleep mapping versus no mapping for high-grade glioma resections: study protocol for an international multicenter prospective three-arm cohort study Open
Introduction The main surgical dilemma during glioma resections is the surgeon’s inability to accurately identify eloquent areas when the patient is under general anaesthesia without mapping techniques. Intraoperative stimulation mapping (…
View article: Maximizing extent of resection while minimizing the risk of neurological morbidity in glioma patients: a novel grading scale to translate these surgical goals into a merged onco-functional clinical outcome
Maximizing extent of resection while minimizing the risk of neurological morbidity in glioma patients: a novel grading scale to translate these surgical goals into a merged onco-functional clinical outcome Open
View article: Response to letter to the editor: “Impact of intraoperative stimulation mapping on high-grade glioma surgery outcome: a meta-analysis”
Response to letter to the editor: “Impact of intraoperative stimulation mapping on high-grade glioma surgery outcome: a meta-analysis” Open
View article: The SAFE-trial: Safe surgery for glioblastoma multiforme: Awake craniotomy versus surgery under general anesthesia. Study protocol for a multicenter prospective randomized controlled trial
The SAFE-trial: Safe surgery for glioblastoma multiforme: Awake craniotomy versus surgery under general anesthesia. Study protocol for a multicenter prospective randomized controlled trial Open
View article: Impact of intraoperative stimulation mapping on high-grade glioma surgery outcome: a meta-analysis
Impact of intraoperative stimulation mapping on high-grade glioma surgery outcome: a meta-analysis Open