Jawaid Ahmed Zai
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View article: Gender Variation of Plasmodium Infection by Different Malarial Testing Techniques in District Hyderabad
Gender Variation of Plasmodium Infection by Different Malarial Testing Techniques in District Hyderabad Open
Background: This study aimed to assess gender-based variation in Plasmodium infection among individuals in the Hyderabad district, using blood smear microscopy, immunochromatographic test (ICT), and real-time PCR (RT-PCR). Methodology: A c…
View article: Next-generation sequencing to genetically diagnose a diverse range of inherited eye disorders in 15 consanguineous families from Pakistan
Next-generation sequencing to genetically diagnose a diverse range of inherited eye disorders in 15 consanguineous families from Pakistan Open
Inherited retinal dystrophies (IRDs) are characterized by photoreceptor dysfunction or degeneration. Clinical and phenotypic overlap between IRDs makes the genetic diagnosis very challenging and comprehensive genomic approaches for accurat…
View article: Vascular endothelial growth factor/platelet ratio as a potential biomarker for preeclampsia: A study of angiogenic markers in Pakistani patients
Vascular endothelial growth factor/platelet ratio as a potential biomarker for preeclampsia: A study of angiogenic markers in Pakistani patients Open
Objectives To determine the levels of angiogenic biomarkers: vascular endothelial growth factor (VEGF), soluble vascular endothelial growth factor receptor 1 (sVEGFR1 or sFlt-1), platelet count, and the VEGF/platelet ratio in preeclampsia.…
View article: Identification of Pathogenic Variants Causes Microcephaly In Sindh Families
Identification of Pathogenic Variants Causes Microcephaly In Sindh Families Open
Introduction: The study was designed to identify the genetic mutation in families with autosomal recessive primary microcephaly (MCPH). Methodology: The present study was cross-sectional and conducted at the Department of Biochemistry, Qua…
View article: Prediction and evaluation of multi epitope based sub-unit vaccine against Salmonella typhimurium
Prediction and evaluation of multi epitope based sub-unit vaccine against Salmonella typhimurium Open
View article: A Missense Variant in LAMA3 Gene Causes Microcephaly and Epidermolysis Bullosa in a Pakistani Family
A Missense Variant in LAMA3 Gene Causes Microcephaly and Epidermolysis Bullosa in a Pakistani Family Open
OBJECTIVE: To identify the disease-causing mutation in a family with autosomal recessive primary microcephaly (MCPH). METHODOLOGY: This cross-sectional study was the continuation of an ongoing family-based study initiated in 2016 at the De…
View article: Assessment of factors responsible for early menopause in Interior Sindh, Pakistan
Assessment of factors responsible for early menopause in Interior Sindh, Pakistan Open
Objective: To evaluate the factors leading to the early onset of menopause (<40 years) in the women in the interior of Sindh.
Materials and Methods: A cross-sectional study was conducted on 218 individuals among them 109 were postmenopaus…
View article: Pilea umbrosa ameliorate CCl4 induced hepatic injuries by regulating endoplasmic reticulum stress, pro-inflammatory and fibrosis genes in rat
Pilea umbrosa ameliorate CCl4 induced hepatic injuries by regulating endoplasmic reticulum stress, pro-inflammatory and fibrosis genes in rat Open
View article: Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats
Methanol extract of Iphiona aucheri ameliorates CCl4 induced hepatic injuries by regulation of genes in rats Open
We have investigated the protective potential of methanol extract of Iphiona aucheri (IAM) on the expression of endoplasmic reticulum (ER) stress associated genes and inflammatory genes on carbon tetrachloride (CCl4) induced hepatic toxici…
View article: Correlation of oxidative stress with 2-hour Plasma Glucose in normal subjects and diabetic families
Correlation of oxidative stress with 2-hour Plasma Glucose in normal subjects and diabetic families Open
Background: There is substantial proof that the hyperglycemia results in generation of reactive oxygen species (ROS), eventually lead to increased oxidative stress in various tissues that results in diabetic complications. This study evalu…