Jay R. Hoffman
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View article: Echoes of the Modern Training Periodization Concepts in Russia Before the October 1917 Revolution
Echoes of the Modern Training Periodization Concepts in Russia Before the October 1917 Revolution Open
Bartolomei, S, Mammadova, G, Manno, R, Haff, GG, Hoffman, JR, and Merni, F. Echoes of the modern training periodization concepts in Russia before the October 1917 revolution. J Strength Cond Res 39(12): 1327–1330, 2025—The debate on the or…
View article: Development and validation of the mobility in middle-age questionnaire
Development and validation of the mobility in middle-age questionnaire Open
Background Mobility decline often begins in midlife, and early identification of individuals at risk of accelerated deterioration can enable timely prevention. However, there is no validated self-report instrument that specifically assesse…
View article: The Effects of Essential Amino Acid Supplementation on Hippocampal Neurotrophin, Dopaminergic and Serotonergic Changes in an Overtraining Mouse Model
The Effects of Essential Amino Acid Supplementation on Hippocampal Neurotrophin, Dopaminergic and Serotonergic Changes in an Overtraining Mouse Model Open
Background/Objectives: This study examined the efficacy of essential amino acid (EAA) supplementation on changes in behavior and hippocampal neurotrophin, dopaminergic and serotonergic markers to a volume overload stress resembling an over…
View article: The effect of nandrolone decanoate administration on fatigue during a volume‐overload stress in male mice
The effect of nandrolone decanoate administration on fatigue during a volume‐overload stress in male mice Open
The effect of nandrolone decanoate on fatigue was examined during a volume‐overload training stress in 3‐month‐old male C57Bl/6J mice ( n = 24). Mice were randomized into two exercising groups and a control group (C). The exercising animal…
View article: Obituary: in memory of the scientific career of Professor Roger C Harris
Obituary: in memory of the scientific career of Professor Roger C Harris Open
View article: A Comparison Between the Traditional and Novel Isometric Mid-Thigh Methods and The Relationship to Countermovement Jump Performance
A Comparison Between the Traditional and Novel Isometric Mid-Thigh Methods and The Relationship to Countermovement Jump Performance Open
The isometric mid-thigh pull (IMTP) test using the traditional bar grip (BAR) is a reliable and effective measure of strength performance in different populations. In addition, IMTP performance has been linked to jump performance. Recent r…
View article: β-Alanine supplementation improves fractional anisotropy scores in the hippocampus and amygdala in 60–80-year-old men and women
β-Alanine supplementation improves fractional anisotropy scores in the hippocampus and amygdala in 60–80-year-old men and women Open
Recently, β-alanine (BA) supplementation was shown to improve cognitive function in older adults with decreased cognitive function. Mechanisms supporting these improvements have not been well defined. This study examined the effects of 10-…
View article: Autoregulation Does Not Provide Additional Benefits to a Mixed Session Periodized Resistance Training Program in Trained Men
Autoregulation Does Not Provide Additional Benefits to a Mixed Session Periodized Resistance Training Program in Trained Men Open
Bartolomei, S, Francesco, L, Latini, D, and Hoffman, JR. Autoregulation does not provide additional benefits to a mixed session periodized resistance training program in trained men. J Strength Cond Res 38(9): 1535–1542, 2024—The aim of th…
View article: Differences in the recovery response from high-intensity and high-volume resistance exercise on force, reactive agility, and cognitive function
Differences in the recovery response from high-intensity and high-volume resistance exercise on force, reactive agility, and cognitive function Open
Purpose This study compared the recovery response of physical performance and cognitive function between high volume, low intensity (HV) and high intensity, low volume (HI) resistance training in resistance trained men. Methods Eight recre…
View article: Early Life Androgen Administration Attenuates Aging Related Declines in Muscle Protein Synthesis
Early Life Androgen Administration Attenuates Aging Related Declines in Muscle Protein Synthesis Open
Purpose This study examined the acute and long-term effects of nandrolone decanoate (ND) on fractional synthetic rates (FSR). Methods Male C57BL/6 mice were randomized into ND ( n = 20) or sham ( n = 20) groups. ND injections (10 g·kg −1 ·…
View article: Short-Term Effects of an American Football Game on Cognitive Function, Memory, and Brain Functional Connectivity
Short-Term Effects of an American Football Game on Cognitive Function, Memory, and Brain Functional Connectivity Open
Introduction/Purpose Head impacts associated with American football have been associated with short- and long-term disrupted cognitive performance. In this study, we aimed to determine the effects of an acute game of American football on c…
View article: The Effect of β-Alanine Supplementation on Performance, Cognitive Function and Resiliency in Soldiers
The Effect of β-Alanine Supplementation on Performance, Cognitive Function and Resiliency in Soldiers Open
β-alanine is a nonessential amino acid that combines with the amino acid histidine to form the intracellular dipeptide carnosine, an important intracellular buffer. Evidence has been well established on the ability of β-alanine supplementa…
View article: Role of β-Alanine Supplementation on Cognitive Function, Mood, and Physical Function in Older Adults; Double-Blind Randomized Controlled Study
Role of β-Alanine Supplementation on Cognitive Function, Mood, and Physical Function in Older Adults; Double-Blind Randomized Controlled Study Open
This study investigated 10 weeks of β-alanine (BA) supplementation on changes in cognitive function, mood, and physical performance in 100 older adults (70.6 ± 8.7 y). Participants were randomized into a BA (2.4 g·d−1) or placebo (PL) grou…
View article: Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature
Supplementation with Nitric Oxide Precursors for Strength Performance: A Review of the Current Literature Open
Nitric-oxide-stimulating dietary supplements are widely available and marketed to strength athletes and weightlifters seeking to increase muscle performance and augment training adaptations. These supplements contain ingredients classified…
View article: Effects of Concurrent Resistance and Endurance Training Using Continuous or Intermittent Protocols on Muscle Hypertrophy: Systematic Review With Meta-Analysis
Effects of Concurrent Resistance and Endurance Training Using Continuous or Intermittent Protocols on Muscle Hypertrophy: Systematic Review With Meta-Analysis Open
Monserdà-Vilaró, A, Balsalobre-Fernández, C, Hoffman, JR, Alix-Fages, C, and Jiménez, SL. Effects of concurrent resistance and endurance training using continuous or intermittent protocols on muscle hypertrophy: Systematic review with meta…
View article: Reliability and Validity of Patient-Reported Outcome Measures for Ankle Instability in Hebrew
Reliability and Validity of Patient-Reported Outcome Measures for Ankle Instability in Hebrew Open
BACKGROUND The International Ankle Consortium has recommended several instruments for assessing and diagnosing chronic ankle instability. These include the Ankle Instability Instrument (AII), Cumberland Ankle Instability Tool (CAIT), Ident…
View article: Examination of Amorphous Calcium Carbonate on the Inflammatory and Muscle Damage Response in Experienced Resistance Trained Individuals
Examination of Amorphous Calcium Carbonate on the Inflammatory and Muscle Damage Response in Experienced Resistance Trained Individuals Open
The effect of 3 weeks of amorphous calcium carbonate (ACC) supplementation (2000 mg per day) was examined on the recovery response to resistance exercise. Thirty men were randomized into a supplement (ACC) or placebo (PL) group. Following …
View article: Heat-Stress Preconditioning Attenuates Behavioral Responses to Psychological Stress: The Role of HSP-70 in Modulating Stress Responses
Heat-Stress Preconditioning Attenuates Behavioral Responses to Psychological Stress: The Role of HSP-70 in Modulating Stress Responses Open
Exposure to high ambient temperature is a stressor that influences both biological and behavioral functions and has been previously shown to have an extensive impact on brain structure and function. Physiological, cellular and behavioral r…
View article: The <i>BDNF</i> Val66Met Polymorphism is a Relevant, But not Determinant, Risk Factor in the Etiology of Neuropsychiatric Disorders – Current Advances in Human Studies: A Systematic Review
The <i>BDNF</i> Val66Met Polymorphism is a Relevant, But not Determinant, Risk Factor in the Etiology of Neuropsychiatric Disorders – Current Advances in Human Studies: A Systematic Review Open
Brain-derived neurotrophic factor (BDNF) is the brain’s most-produced neurotrophin during the lifespan, essentially involved in multiple mechanisms of nervous system development and function. The production/release of BDNF requires multi-s…
View article: The Immediate Carryover Effects of Peroneal Functional Electrical Stimulation Differ between People with and without Chronic Ankle Instability
The Immediate Carryover Effects of Peroneal Functional Electrical Stimulation Differ between People with and without Chronic Ankle Instability Open
Chronic ankle instability (CAI) is a common condition that may develop after an ankle sprain. Compared with healthy individuals, those with CAI demonstrate excessive ankle inversion and increased peroneal electromyography (EMG) activity th…
View article: Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations
Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations Open
Elevations in the circulating concentration of androgens are thought to have a positive effect on the anabolic processes leading to improved athletic performance. Anabolic-androgenic steroids have often been used by competitive athletes to…
View article: Anabolic-Androgenic Steroid Use in Sports, Health, and Society
Anabolic-Androgenic Steroid Use in Sports, Health, and Society Open
This consensus statement is an update of the 1987 American College of Sports Medicine (ACSM) position stand on the use of anabolic-androgenic steroids (AAS). Substantial data have been collected since the previous position stand, and AAS u…
View article: The Val66 and Met66 Alleles-Specific Expression of BDNF in Human Muscle and Their Metabolic Responsivity
The Val66 and Met66 Alleles-Specific Expression of BDNF in Human Muscle and Their Metabolic Responsivity Open
Brain-derived neurotrophic factor (BDNF) plays an essential role in nervous system formation and functioning, including metabolism. Present only in humans, the “Val66Met” polymorphism of the BDNF gene ( BDNF ) is suggested to have a negati…
View article: Exercise-induced muscle damage: mechanism, assessment and nutritional factors to accelerate recovery
Exercise-induced muscle damage: mechanism, assessment and nutritional factors to accelerate recovery Open
View article: Continuous and interval training attenuate encephalomyelitis by separate immunomodulatory mechanisms
Continuous and interval training attenuate encephalomyelitis by separate immunomodulatory mechanisms Open
Background Studies have reported beneficial effects of exercise training on autoimmunity, and specifically on multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). However, it is unknown whether different training pa…
View article: Agreement of Gait Events Detection during Treadmill Backward Walking by Kinematic Data and Inertial Motion Units
Agreement of Gait Events Detection during Treadmill Backward Walking by Kinematic Data and Inertial Motion Units Open
Backward walking (BW) is being increasingly used in neurologic and orthopedic rehabilitation as well as in sports to promote balance control as it provides a unique challenge to the sensorimotor control system. The identification of initia…
View article: Effect of somatic maturity on the aerobic and anaerobic adaptations to sprint interval training
Effect of somatic maturity on the aerobic and anaerobic adaptations to sprint interval training Open
The purpose of this study was to assess the maturity-related differences in the aerobic and anaerobic adaptations to sprint interval training (SIT) among youth male athletes. Twenty-seven youth male athletes were assessed for years from pe…
View article: Effects of resistance training on classic and specific bioelectrical impedance vector analysis in elderly women
Effects of resistance training on classic and specific bioelectrical impedance vector analysis in elderly women Open
Raw bioelectrical impedance analysis (BIA) data [resistance (R); reactance (Xc)] through bioelectrical impedance vector analysis (BIVA) and phase angle (PhA) have been used to evaluate cellular function and hydration status. The purpose of…
View article: A Comparison Between Total Body and Split Routine Resistance Training Programs in Trained Men
A Comparison Between Total Body and Split Routine Resistance Training Programs in Trained Men Open
Bartolomei, S, Nigro, F, Malagoli Lanzoni, I, Masina, F, Di Michele, R, and Hoffman, JR. A comparison between total body and split routine resistance training programs in trained men. J Strength Cond Res 35(6): 1520–1526, 2021—The purpose …