Jayashree Rajamanickam
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View article: Evaluation of [ <sup>11</sup> C]CS1P1 in Healthy Young and Older Adults
Evaluation of [ <sup>11</sup> C]CS1P1 in Healthy Young and Older Adults Open
In this study, we have established a quantitative 11C]CS1P1 PET processing approach by using a 2-tissue compartment model and imaging-derived input function with population metabolite correction. [11C]CS1P1 PET reflec…
View article: Twelve Weeks of Intermittent Caloric Restriction Diet Mitigates Neuroinflammation in Midlife Individuals with Multiple Sclerosis: A Pilot Study with Implications for Prevention of Alzheimer’s Disease
Twelve Weeks of Intermittent Caloric Restriction Diet Mitigates Neuroinflammation in Midlife Individuals with Multiple Sclerosis: A Pilot Study with Implications for Prevention of Alzheimer’s Disease Open
Background: Multiple sclerosis (MS) is a prototype neuroinflammatory disorder with increasingly recognized role for neurodegeneration. Most first-line treatments cannot prevent the progression of neurodegeneration and the resultant disabil…
View article: An update on the safety of current therapies for Alzheimer’s disease: focus on rivastigmine
An update on the safety of current therapies for Alzheimer’s disease: focus on rivastigmine Open
Alzheimer’s disease (AD) is the most common cause of major neurocognitive disorders worldwide. Despite all research efforts, therapeutic options for AD are still limited to two drug classes: cholinesterase inhibitors (ChEIs) and the NMDA-r…