Stephen P. Luby
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View article: Associations Between Micronutrient Status, Hormones, and Immune Status During Pregnancy and Child Growth in Rural Bangladesh: A Prospective Cohort Study
Associations Between Micronutrient Status, Hormones, and Immune Status During Pregnancy and Child Growth in Rural Bangladesh: A Prospective Cohort Study Open
View article: A framework for guiding integrated disease control measures through multipathogen surveillance
A framework for guiding integrated disease control measures through multipathogen surveillance Open
Global health programs have traditionally focused on single diseases. There is potential for synergy through integrated intervention delivery, particularly in areas with overlapping geographic disease burden, but there is limited methodolo…
View article: Beyond Acute Jaundice: refining case definitions for suspected hepatitis E in South Sudan and Bangladesh
Beyond Acute Jaundice: refining case definitions for suspected hepatitis E in South Sudan and Bangladesh Open
Summary The true burden of hepatitis E is poorly understood due to a lack of routine diagnostic testing and nonspecific symptoms. We evaluated the sensitivity and specificity of international case definitions for suspected hepatitis E and …
View article: Perinatal colonization with extended-spectrum beta-lactamase-producing and carbapenem-resistant gram-negative bacteria among home births in Bangladesh
Perinatal colonization with extended-spectrum beta-lactamase-producing and carbapenem-resistant gram-negative bacteria among home births in Bangladesh Open
Background Neonatal infections are increasingly caused by antibiotic-resistant bacteria. It is unknown to what extent home-based births, which account for nearly a third of deliveries in Bangladesh, may also result in exposure to antibioti…
View article: Epidemiology, clinical characteristics, and genetic diversity of Nipah virus strains from Bangladesh: 2016-2023
Epidemiology, clinical characteristics, and genetic diversity of Nipah virus strains from Bangladesh: 2016-2023 Open
View article: Associations between floor material and E. coli contamination in rural Bangladeshi households
Associations between floor material and E. coli contamination in rural Bangladeshi households Open
Measures to control enteric infections in low-income countries should test flooring improvements to reduce exposure to fecal contamination.
View article: National burden and optimal vaccine policy for Japanese encephalitis virus in Bangladesh
National burden and optimal vaccine policy for Japanese encephalitis virus in Bangladesh Open
Background Bangladesh first reported Japanese encephalitis virus (JEV) in 1977 and has seen regular cases since, however, no JEV vaccination program currently exists. A barrier to the use of JEV vaccines has been a limited understanding of…
View article: Evaluation of a multicomponent child development intervention delivered through the government health system: a feasibility study
Evaluation of a multicomponent child development intervention delivered through the government health system: a feasibility study Open
Introduction Small efficacy trials have demonstrated that multicomponent interventions can improve early child development. We evaluated the large-scale delivery of a multicomponent intervention delivered by government health workers throu…
View article: Adolescent psychological health, temporal discounting, and climate distress under increased flood exposure in Bangladesh: a mixed-methods cross-sectional study
Adolescent psychological health, temporal discounting, and climate distress under increased flood exposure in Bangladesh: a mixed-methods cross-sectional study Open
View article: Antispike IgG antibody decay after immunisation with fractional versus full booster doses of COVID-19 vaccines: a 6-month longitudinal analysis of the FRACT-COV trial in Brazil
Antispike IgG antibody decay after immunisation with fractional versus full booster doses of COVID-19 vaccines: a 6-month longitudinal analysis of the FRACT-COV trial in Brazil Open
Objectives To compare antispike IgG levels over a period of 182 days of follow-up in healthy adults who received full or fractional booster doses of BNT162b2 or AZD1222 after completing a primary series of Sinovac, BNT162b2 or AZD1222. Des…
View article: Adult hospitalizations due to hepatitis A virus infection in six tertiary hospitals across Bangladesh: December 2014 to September 2017
Adult hospitalizations due to hepatitis A virus infection in six tertiary hospitals across Bangladesh: December 2014 to September 2017 Open
Hepatitis A virus (HAV) is spread through the fecal-oral route. The age of infection largely determines the clinical severity; children typically have asymptomatic or mild illness, but infected adults more commonly develop clinical disease…
View article: Evaluating the accuracy of<i>Salmonella</i>Typhi Hemolysin E and lipopolysaccharide IgA to discriminate enteric fever from other febrile illnesses in South Asia
Evaluating the accuracy of<i>Salmonella</i>Typhi Hemolysin E and lipopolysaccharide IgA to discriminate enteric fever from other febrile illnesses in South Asia Open
Existing methods to identify patients infected with Salmonella enterica Typhi (S. Typhi) or Paratyphi are inadequately accurate, affordable, and efficient. We evaluated the discriminatory power of antibodies to S. Typhi hemolysin E (HlyE) …
View article: Impact of the COVID-19 pandemic and typhoid conjugate vaccine introduction on typhoid fever in Nepal
Impact of the COVID-19 pandemic and typhoid conjugate vaccine introduction on typhoid fever in Nepal Open
Background While typhoid conjugate vaccines (TCV) offer promise for reducing risk in endemic settings, their population-level impact remains unclear. In 2022, Nepal introduced TCV nationally on the heels of the COVID-19 pandemic, which dis…
View article: Using machine learning to identify subgroups with the highest expected benefit in a population-based water, sanitation, handwashing, and nutrition intervention
Using machine learning to identify subgroups with the highest expected benefit in a population-based water, sanitation, handwashing, and nutrition intervention Open
Background: Understanding who benefits most from investments in water, sanitation, and hygiene (WaSH) interventions can elucidate causal pathways, uncover complex interactions between population characteristics and interventions, and infor…
View article: Assessing equity in effects of nutritional supplementation for child growth, development, and anemia
Assessing equity in effects of nutritional supplementation for child growth, development, and anemia Open
Undernutrition in early childhood causes stunted growth, cognitive delays, and anemia, with effects often magnified among children from the poorest households. Small-quantity lipid-based nutrient supplements (SQ-LNS) are effective in addre…
View article: Biomarkers of environmental enteric dysfunction and neurodevelopmental outcomes among children in rural Bangladesh and Kenya: a prospective cohort study
Biomarkers of environmental enteric dysfunction and neurodevelopmental outcomes among children in rural Bangladesh and Kenya: a prospective cohort study Open
View article: Perinatal colonization with extended-spectrum beta-lactamase-producing and carbapenem-resistant Gram-negative bacteria among home births in Bangladesh
Perinatal colonization with extended-spectrum beta-lactamase-producing and carbapenem-resistant Gram-negative bacteria among home births in Bangladesh Open
Background Hospital-acquired neonatal infections are increasingly caused by antibiotic-resistant bacteria. It is unknown to what extent home-based births, which account for nearly a third of deliveries in Bangladesh, may also result in exp…
View article: Associations between floor material and <i>E. coli</i> contamination in rural Bangladeshi households
Associations between floor material and <i>E. coli</i> contamination in rural Bangladeshi households Open
Soil floors are common in low-income countries and can harbor contamination from unsafely managed human and animal fecal waste. Soil/dust ingestion directly from floors or indirectly via hands, drinking water and food can significantly con…
View article: Associations Between Intimate Partner Violence, Depression, Perceived Stress, and Child Growth
Associations Between Intimate Partner Violence, Depression, Perceived Stress, and Child Growth Open
View article: Changes in enteric fever trends during the COVID-19 pandemic from the Surveillance for Enteric Fever in Asia Project: a cross-sectional study
Changes in enteric fever trends during the COVID-19 pandemic from the Surveillance for Enteric Fever in Asia Project: a cross-sectional study Open
View article: Population-Based Estimates of Hepatitis E Virus–Associated Mortality in Bangladesh
Population-Based Estimates of Hepatitis E Virus–Associated Mortality in Bangladesh Open
Background Hepatitis E virus (HEV) is endemic in many resource-poor countries. Despite an available vaccine, data on HEV-associated mortality are scarce, hindering informed decisions. This study aims to estimate the population-based rate o…
View article: Effects of an early water, sanitation, hygiene, and nutritional intervention on child development at school age: a 7-year follow-up of a cluster-randomized trial in rural Bangladesh
Effects of an early water, sanitation, hygiene, and nutritional intervention on child development at school age: a 7-year follow-up of a cluster-randomized trial in rural Bangladesh Open
Background A previous cluster-randomized controlled trial in Bangladesh found that individual or combined water, handwashing, sanitation, and nutrition interventions during pregnancy and after birth improved developmental outcomes of child…
View article: Immunogenicity and reactogenicity of fractional vs. full booster doses of COVID-19 vaccines: a non-inferiority, randomised, double-blind, phase IV clinical trial in Brazil
Immunogenicity and reactogenicity of fractional vs. full booster doses of COVID-19 vaccines: a non-inferiority, randomised, double-blind, phase IV clinical trial in Brazil Open
Coalition for Epidemic Preparedness Innovations (CEPI)/Sabin Vaccine Institute.
View article: Treatment heterogeneity of water, sanitation, hygiene, and nutrition interventions on child growth by environmental enteric dysfunction and pathogen status for young children in Bangladesh
Treatment heterogeneity of water, sanitation, hygiene, and nutrition interventions on child growth by environmental enteric dysfunction and pathogen status for young children in Bangladesh Open
Background Water, sanitation, hygiene (WSH), nutrition (N), and combined (N+WSH) interventions are often implemented by global health organizations, but WSH interventions may insufficiently reduce pathogen exposure, and nutrition intervent…
View article: Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya
Water, sanitation, handwashing, and nutritional interventions can reduce child antibiotic use: evidence from Bangladesh and Kenya Open
Antibiotics can trigger antimicrobial resistance and microbiome alterations. Reducing pathogen exposure and undernutrition can reduce infections and antibiotic use. We assess effects of water, sanitation, handwashing (WSH) and nutrition in…
View article: Community Willingness to Participate in a Nipah Vaccine Trial in Bangladesh
Community Willingness to Participate in a Nipah Vaccine Trial in Bangladesh Open
View article: Impacts of a Sustained, Large-Scale Liquefied Petroleum Gas (LPG) Cooking Intervention in the Rohingya Refugee Camp on Time Use, Household Air Pollution, and Health
Impacts of a Sustained, Large-Scale Liquefied Petroleum Gas (LPG) Cooking Intervention in the Rohingya Refugee Camp on Time Use, Household Air Pollution, and Health Open
View article: Examining the Effect of Neighborhood Sanitation Coverage on Childhood Diarrheal Disease in Rural Bangladesh
Examining the Effect of Neighborhood Sanitation Coverage on Childhood Diarrheal Disease in Rural Bangladesh Open
View article: Correction to: Nipah Outbreak Investigation in Bangladesh, 2007: A Case Study of One Health Partnership and Intersectoral Coordination
Correction to: Nipah Outbreak Investigation in Bangladesh, 2007: A Case Study of One Health Partnership and Intersectoral Coordination Open
View article: Large-Scale Distribution of Liquified Petroleum Gas in Bangladesh's Rohingya Refugee Camp: Uptake, Reductions in Deforestation, and Carbon Financing Potential
Large-Scale Distribution of Liquified Petroleum Gas in Bangladesh's Rohingya Refugee Camp: Uptake, Reductions in Deforestation, and Carbon Financing Potential Open