Jean Baptiste Hzounda Fokou
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View article: Discovery and structure–activity relationship analysis of 2-Pyridyl Thieno[3,2-d]pyrimidine derivatives as promising therapeutic candidates for the treatment of Buruli ulcer
Discovery and structure–activity relationship analysis of 2-Pyridyl Thieno[3,2-d]pyrimidine derivatives as promising therapeutic candidates for the treatment of Buruli ulcer Open
Mycobacterium ulcerans , the bacterium causing Buruli ulcer (BU), can potentially develop resistance to existing antibiotics (rifampicin - clarithromycin/ moxifloxacin), underscoring the need for new antimycobacterial treatments. This stud…
View article: How do dietary supplements and drugs affect bodybuilders in Cameroon?
How do dietary supplements and drugs affect bodybuilders in Cameroon? Open
View article: <i>Cylicodiscus gabunensis</i>(FABACEAE) aqueous stem bark extract mediated silver nanoparticle enhance anti-inflammation on Wistar rats
<i>Cylicodiscus gabunensis</i>(FABACEAE) aqueous stem bark extract mediated silver nanoparticle enhance anti-inflammation on Wistar rats Open
Introduction Plants are a source of bioactive ingredient that can play a key role in development of new drugs. In recent years, plant mediated-biological synthesis of nanoparticles has gained importance due to its simplicity, cost effectiv…
View article: In vitro anti-trypanosomal activity of crude extract and fractions of <i>Trichoscypha acuminata</i> stem bark, <i>Spathodea campanulata</i> flowers, and <i>Ficus elastica</i> lianas on <i>Trypanosoma brucei brucei</i>
In vitro anti-trypanosomal activity of crude extract and fractions of <i>Trichoscypha acuminata</i> stem bark, <i>Spathodea campanulata</i> flowers, and <i>Ficus elastica</i> lianas on <i>Trypanosoma brucei brucei</i> Open
The low therapeutic index of available trypanocidal drugs and the increasing emergence of resistant Trypanosoma parasites indicate the urgent need to develop new strategies for trypanosomiasis control. One such strategy is the screening o…
View article: Anti-inflammation study of cellulose-chitosan biocomposite-based Tetrapleura tetraptera (Taub) dried fruits aqueous extract
Anti-inflammation study of cellulose-chitosan biocomposite-based Tetrapleura tetraptera (Taub) dried fruits aqueous extract Open
Nanotechnology is making exceptional progress in the medical field. The development of new systems for the delivery of plant ingredients brings benefits such as good bioavailability, solubility, sustained release, and enhanced potential. T…
View article: Anti-candida activities of four bacterial endophytic extracts isolated from Urena lobata.
Anti-candida activities of four bacterial endophytic extracts isolated from Urena lobata. Open
Purpose: Most antifungals have drawbacks, including toxicity, efficacy, and cost, and their misuse has led to the emergence of resistant strains.Therefore, more is needed.This study aimed to evaluate the antifungal properties of bacterial …
View article: The wound healing property of encapsulated silver nanoparticles made from aqueous extracts of Elaeis guineensis Jacq leaves
The wound healing property of encapsulated silver nanoparticles made from aqueous extracts of Elaeis guineensis Jacq leaves Open
A wound can be defined as the disruption of the normal integrity of the body. the management of wounds usually ends up with scars that can cause functional harm and emotional and social distress. All these urge the need for new approaches …
View article: Comparative Anti-plasmodial and Cytotoxic Effect of the Methanolic Extracts of Leaves, Stem Bark and Roots of Annickia affinis
Comparative Anti-plasmodial and Cytotoxic Effect of the Methanolic Extracts of Leaves, Stem Bark and Roots of Annickia affinis Open
Aims: This study aimed to evaluate and compare the in vitro anti-plasmodial and cytotoxic effect of the methanolic extracts from leaves, stem bark and roots of Annickia affinis.
Study Design: This is an experimental study.
Place and Dura…
View article: Etiology and clinical characteristics of pediatric acute fever among hospitalized children in an endemic malaria transmission area of Cameroon in Central Africa
Etiology and clinical characteristics of pediatric acute fever among hospitalized children in an endemic malaria transmission area of Cameroon in Central Africa Open
Acute fever in the majority of children in resource-limited countries is attributable to malaria and often treated without laboratory evidence. The aim of the study was to characterize acute pediatric infectious fevers (APIF) in the pediat…
View article: Phytochemical analysis, assessment of acute and subacute toxicological profile of the ethanolic extract of Ficus elastica Roxb. Ex Hornem (Moraceae) lianas in experimental Wistar rats
Phytochemical analysis, assessment of acute and subacute toxicological profile of the ethanolic extract of Ficus elastica Roxb. Ex Hornem (Moraceae) lianas in experimental Wistar rats Open
Ficus elastica Roxb. Ex Hornem, also called Rubber fig tree is a plant of the Moraceae family widely used in traditional medicine for the treatment of various ailments including allergies and skin infections, as well as a diuretic agent. T…
View article: Wound healing and immunomodulatory effects of juice from Bidens pilosa fresh leaves
Wound healing and immunomodulatory effects of juice from Bidens pilosa fresh leaves Open
In response to a wound, a physiological restoration phenomenon occurs wound healing. This phenomenon can evade the body’s control and lead to a wide range of disability. A major drawback of modern wound-healing drugs is their accessibility…
View article: Characterization and Quantification of Phenolic Compounds of Hydroethanolic Extracts and Fractions of Leaves &lt;i&gt;Gnetum africanum&lt;/i&gt; (Welv.) and &lt;i&gt;Gnetum buchholzianum&lt;/i&gt; (Engl.) (Gnetaceae)
Characterization and Quantification of Phenolic Compounds of Hydroethanolic Extracts and Fractions of Leaves <i>Gnetum africanum</i> (Welv.) and <i>Gnetum buchholzianum</i> (Engl.) (Gnetaceae) Open
Research for bioactive molecules and not resistant to infectious agents remains topical for science. The total polyphenols (TPP) and total flavonoids (TFv) of the hydroethanolic extracts and fractions obtained were quantified according to …
View article: In Vitro Antioxidant and Anti-inflammatory Potential of the Optimized Combinations of Essential Oils from Three Cameroon Grew Ocimum L.
In Vitro Antioxidant and Anti-inflammatory Potential of the Optimized Combinations of Essential Oils from Three Cameroon Grew Ocimum L. Open
View article: Essential Oil’s Chemical Composition and Pharmacological Properties
Essential Oil’s Chemical Composition and Pharmacological Properties Open
Essential oil, sent by nature, is a complex mixture of volatile secondary metabolites. Its composition varies along with many parameters that can lead to misunderstanding of its wonderful pharmacological property. In fact, from post-harves…
View article: Anti-yeast potential of some Annonaceae species from Cameroonian biodiversity
Anti-yeast potential of some Annonaceae species from Cameroonian biodiversity Open
An increased incidence of candidiasis and cryptococcosis has been recorded within the last two decades, mainly due to the increase in number of immunocompromised patients. Moreover, the emergence of resistant pathogenic yeast strains coupl…
View article: Phytochemical analysis and antioxidant activities of <i>Combretum molle</i> and <i>Pericopsis laxiflora</i>
Phytochemical analysis and antioxidant activities of <i>Combretum molle</i> and <i>Pericopsis laxiflora</i> Open
In Burkina Faso as in several African countries, diabetes is becoming a very serious disease and public concern. Patients use both drugs and plants for treatment. Thus, Combretum molle and Pericopsis laxiflora have been identified as plant…
View article: Antiradical, Anti-inflammatory and Antifungal Activities of Essential Oils of Two Aromatic Plants: Apium graveolens (Apiaceae) and Thymus vulgaris (Lamiaceae)
Antiradical, Anti-inflammatory and Antifungal Activities of Essential Oils of Two Aromatic Plants: Apium graveolens (Apiaceae) and Thymus vulgaris (Lamiaceae) Open
The outbreak of oxidative stress, inflammatory diseases and mycoses, constitute an important public health problem. This could be due to the increase of risk factors, side effects and expensive therapeutic molecules available. In the aim t…