Jean Baptiste Nyandwi
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View article: Hypoglycemia and associated cardiovascular diseases, morbidity and mortality in patients with type 2 diabetes mellitus in university teaching hospitals in Rwanda
Hypoglycemia and associated cardiovascular diseases, morbidity and mortality in patients with type 2 diabetes mellitus in university teaching hospitals in Rwanda Open
Background Hypoglycemia is a common yet underrecognized complication in patients with type 2 diabetes mellitus (T2DM), often linked with increased cardiovascular (CV) morbidity and mortality. Despite its clinical importance, there is a lim…
View article: Evaluating the contribution of a new electronic logistics management information system on the availability of HIV, TB and Malaria commodities in public hospitals in Uganda
Evaluating the contribution of a new electronic logistics management information system on the availability of HIV, TB and Malaria commodities in public hospitals in Uganda Open
Background Effective management of HIV, TB, and malaria requires reliable access to essential medicines, which is still a significant challenge in low and middle-income countries. This study aimed to assess the effect of the National Medic…
View article: Advancing Vaccinology Capacity: Education and Efforts in Vaccine Development and Manufacturing across Africa
Advancing Vaccinology Capacity: Education and Efforts in Vaccine Development and Manufacturing across Africa Open
Africa, home to the world’s second-largest population of approximately 1.3 billion, grapples with significant challenges in meeting its medical needs, particularly in accessing quality healthcare services and products. The continent faces …
View article: Advancing Vaccinology Capacity: Education and Efforts in Vaccine Development and Manufacturing across Africa
Advancing Vaccinology Capacity: Education and Efforts in Vaccine Development and Manufacturing across Africa Open
Africa, home to the world's second-largest population of approximately 1.3 billion, grapples with significant challenges in meeting its medical needs, particularly in accessing quality healthcare services and products. The continent f…
View article: Vaccination and vaccine-preventable diseases in Africa
Vaccination and vaccine-preventable diseases in Africa Open
Introduction: Efforts to reduce the global burden of communicable and non-communicable diseases can significantly benefit from comprehensive immunisation programmes. Organisations such as the World Health Organization (WHO), regional partn…
View article: Assessment of community pharmacies readiness to dispense antiretroviral medicines in Rwanda
Assessment of community pharmacies readiness to dispense antiretroviral medicines in Rwanda Open
Community pharmacies in Rwanda have majority of staff trained in various areas of HIV prevention, but a small proportion have been trained in HIV care and treatment. Community pharmacies have the necessary infrastructure to dispense ARVs, …
View article: Prevalence of Post COVID-19 Condition among Healthcare Workers: Self-Reported Online Survey in Four African Countries, December 2021–January 2022
Prevalence of Post COVID-19 Condition among Healthcare Workers: Self-Reported Online Survey in Four African Countries, December 2021–January 2022 Open
The impact of Post COVID-19 Condition (PCC) is ongoing despite the declaration that the 2019 COVID-19 pandemic has ended. In this study, we explore the prevalence of PCC among healthcare workers (HCWs) in four African Countries and its inf…
View article: Request for Antimalarial Medicines and Their Dispensing Without a Prescription in Community Pharmacies in Rwanda
Request for Antimalarial Medicines and Their Dispensing Without a Prescription in Community Pharmacies in Rwanda Open
Dispensing antimalarial medicines without prescriptions is a common practice in community pharmacies in Rwanda. The main factors contributing to this practice include lack of awareness regarding the classification of antimalarials as presc…
View article: Malaria rapid diagnostic tests in community pharmacies in Rwanda: availability, knowledge of community pharmacists, advantages, and disadvantages of licensing their use
Malaria rapid diagnostic tests in community pharmacies in Rwanda: availability, knowledge of community pharmacists, advantages, and disadvantages of licensing their use Open
Background Presumptive treatment of malaria is often practiced in community pharmacies across sub-Saharan Africa (SSA).To address this issue, the World Health Organization (WHO) recommends that malaria Rapid Diagnostic Tests (m-RDTs) be us…
View article: Prevalence of Post COVID-19 Condition among healthcare workers: self-reported online survey in four African countries
Prevalence of Post COVID-19 Condition among healthcare workers: self-reported online survey in four African countries Open
The impact of Post COVID-19 Condition is ongoing despite the WHO declaration that the pandemic has ended. In this study, we explore the prevalence of PCC among healthcare workers (HCWs) in four African Countries and its influence on their …
View article: Critical Appraisal of Mpox (Monkeypox) in Africa using Scoping and Systematic Reviews: Epidemiology, Biochemistry, Phylogeny, Pathogenesis, Clinical Features, Diagnosis, Treatment, Biosecurity and One-Health
Critical Appraisal of Mpox (Monkeypox) in Africa using Scoping and Systematic Reviews: Epidemiology, Biochemistry, Phylogeny, Pathogenesis, Clinical Features, Diagnosis, Treatment, Biosecurity and One-Health Open
Although the WHO declared Mpox (monkeypox) as the 7th aetiology of public health emergency of international concern (PHEIC) in 2022, Africa remains a battlefield for the emergence and re-emergence of deadly aetiologies including the Lassa …
View article: Cold chain management practices of non-vaccine commodities in public health facilities of Rwenzori Region, Western Uganda
Cold chain management practices of non-vaccine commodities in public health facilities of Rwenzori Region, Western Uganda Open
The management practices for non-vaccine cold chain commodities in health centers were fair. More than a third of the facility store managers lacked knowledge on cold chain management practices for non-vaccine commodities. There is a need …
View article: Vaccine management practices among healthcare workers in Morogoro, Tanzania: a cross-sectional study
Vaccine management practices among healthcare workers in Morogoro, Tanzania: a cross-sectional study Open
Background Effective vaccine management is essential to maintain the quality of vaccines, minimise wastages, and prevent missed opportunities for vaccination at service delivery points. Objectives This study aims to assess vaccine manageme…
View article: Public Health Surveillance for Adverse Events Following COVID-19 Vaccination in Africa
Public Health Surveillance for Adverse Events Following COVID-19 Vaccination in Africa Open
Local, national, and international health agencies have advocated multi-pronged public health strategies to limit infections and prevent deaths. The availability of safe and effective vaccines is critical in the control of a pandemic. Seve…
View article: Rosmarinic acid downregulates the oxLDL‑induced interaction between monocytes and endothelial cells, in addition to monocyte diapedesis, under high glucose conditions
Rosmarinic acid downregulates the oxLDL‑induced interaction between monocytes and endothelial cells, in addition to monocyte diapedesis, under high glucose conditions Open
Endothelial dysfunction during diabetes has been previously reported to be at least in part attributed to increased oxidized low‑density lipoprotein (oxLDL) levels mediated by high glucose (HG) levels. Endothelial inflammation increases th…
View article: Investigation of the Quality of the 12 Most-Used Antibiotics Available in Retail Private Pharmacies in Rwanda
Investigation of the Quality of the 12 Most-Used Antibiotics Available in Retail Private Pharmacies in Rwanda Open
Using poor-quality antibiotics leads to increased risk of the development of microorganism-resistant strains, treatment failure, loss of confidence in health systems, and associated socio-economic impacts. The prevalence of poor-quality an…
View article: PUBLIC HEALTH SURVEILLANCE FOR ADVERSE EVENTS FOLLOWING COVID-19 VACCINATION IN AFRICA
PUBLIC HEALTH SURVEILLANCE FOR ADVERSE EVENTS FOLLOWING COVID-19 VACCINATION IN AFRICA Open
Background : The death toll and economic disaster caused by SARS-CoV-2/ COVID-19 is still on the rise globally and in Africa with a case fatality ratio (CFR), 2.58 from 220,958 deaths out of 8,556,890 cases recorded across the continent as…
View article: Will Africans take COVID-19 vaccination?
Will Africans take COVID-19 vaccination? Open
The economic and humanistic impact of COVID-19 pandemic is enormous globally. No definitive treatment exists, hence accelerated development and approval of COVID-19 vaccines, offers a unique opportunity for COVID-19 prevention and control.…
View article: Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice
Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice Open
Hyperlipidemia is a potent risk factor for the development of cardiovascular diseases. The reverse cholesterol transport (RCT) process has been shown to alleviate hyperlipidemia and protect against cardiovascular diseases. Recently, rosmar…
View article: Rosmarinic Acid Increases Macrophage Cholesterol Efflux through Regulation of ABCA1 and ABCG1 in Different Mechanisms
Rosmarinic Acid Increases Macrophage Cholesterol Efflux through Regulation of ABCA1 and ABCG1 in Different Mechanisms Open
Lipid dysregulation in diabetes mellitus escalates endothelial dysfunction, the initial event in the development and progression of diabetic atherosclerosis. In addition, lipid-laden macrophage accumulation in the arterial wall plays a sig…
View article: Will Africans Take COVID-19 Vaccination?
Will Africans Take COVID-19 Vaccination? Open
View article: Availability, accessibility, and quality of adolescent Sexual and Reproductive Health (SRH) services in urban health facilities of Rwanda: a survey among social and healthcare providers
Availability, accessibility, and quality of adolescent Sexual and Reproductive Health (SRH) services in urban health facilities of Rwanda: a survey among social and healthcare providers Open
View article: Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health (SRH) Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers
Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health (SRH) Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers Open
Background : Adolescents are still getting pregnant and contracting Human Immunodeficiency Virus (HIV) and Sexually Transmitted Infections (STIs) in Rwanda as elsewhere. Quality and comprehensive SRH services and information for adolescent…
View article: Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health (SRH) Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers
Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health (SRH) Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers Open
Background : Adolescents are still getting pregnant and contracting Human Immunodeficiency Virus (HIV) and Sexually Transmitted Infections (STIs) in Rwanda as elsewhere. Quality and comprehensive SRH services and information for adolescent…
View article: Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers
Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers Open
Background : Access and utilization of quality and comprehensive sexual and reproductive health services (SRHS) is crucial for the health of young adolescents worldwide. This study assessed the quality of SRHS provided to Rwandan adolescen…
View article: Perceptions and barriers toward sexual reproductive health services accessibility, availability and quality among adolescents in selected cities of Rwanda
Perceptions and barriers toward sexual reproductive health services accessibility, availability and quality among adolescents in selected cities of Rwanda Open
Background: A fifth of the global population is made up of adolescents. Sexual reproductive health needs for young people is largely ignored by existing health, education and other social programs. In Rwanda, there is still an increase in …
View article: Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers
Availability, Accessibility, and Quality of Adolescent Sexual and Reproductive Health Services in Urban Health Facilities of Rwanda: A survey among social and healthcare providers Open
Background : Access and utilization of quality and comprehensive sexual and reproductive health services (SRHS) is a very crucial point for young adolescents worldwide. This study assessed the quality of SRHS provided to Rwandan adolescent…
View article: Knowledge and Practice of Hormonal Contraception among High School Teens
Knowledge and Practice of Hormonal Contraception among High School Teens Open
View article: Breast Cancer and Breast Self-examination: Awareness and Practice among Secondary School Girls in Nyarugenge District, Rwanda
Breast Cancer and Breast Self-examination: Awareness and Practice among Secondary School Girls in Nyarugenge District, Rwanda Open
Aims: To assess the level of early sensitization and education of adolescent high school girls in Rwanda about Breast Cancer (BC) and Breast Self-Examination (BSE) as one of strategic approaches to reduce the risk of late intervention and …
View article: Sexual Activity and Emergency Contraception among Female Students in the University of Rwanda
Sexual Activity and Emergency Contraception among Female Students in the University of Rwanda Open