Explanipedia

Mini-Invasive Pleural Probe-Based Confocal Laser Endomicroscopy for Malignant Pleural Effusion Diagnosis Open

Olivier Bonhomme, Vincent Heinen, Jean-Louis Corhay, Renaud Louis, Nancy Detrembleur , et al. · 2025

Introduction: Probe-based confocal laser endomicroscopy (pCLE) is an optical imaging tool which allows live imaging tissues at cellular level. pCLE proved to be able to discriminate malignant from benign pleura during medical thoracoscopy …

Utility of bronchoalveolar lavage for COVID-19: a perspective from the Dragon consortium Open

Sara Tomassetti, Luca Ciani, Valentina Luzzi, Leonardo Gori, Marco Trigiani , et al. · 2024

Diagnosing COVID-19 and treating its complications remains a challenge. This review reflects the perspective of some of the Dragon (IMI 2-call 21, #101005122) research consortium collaborators on the utility of bronchoalveolar lavage (BAL)…

Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis Open

Julien Guiot, Monique Henket, Marie Ernst, Laurence Seidel, Marie Winandy , et al. · 2023

Objectives In our study, we explored the specific subgroup of patients with rheumatoid arthritis (RA) suffering from obstructive lung disease (OLD) and its impact on morbi-mortality. Methods Our retrospective study included 309 patients su…

Utility of bronchoalveolar lavage for COVID-19: a perspective from the Dragon consortium. Open

Sara Tomassetti, Luca Ciani, Valentina Luzzi, Leonardo Gori, Leonardo Giuntoli , et al. · 2022

Diagnosing COVID-19 and treating its complications remains a challenge. This review reflects the perspective of some of the Dragon (IMI 2-call 21, #101005122) research consortium collaborators on the utility of bronchoalveolar lavage (BAL)…

Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking Open

Maude A. Liegeois, Qiang Baï, Laurence Fiévez, Dimitri Pirottin, Céline Legrand , et al. · 2022

Alveolar macrophages (AMs) are functionally important innate cells involved in lung homeostasis and immunity and whose diversity in health and disease is a subject of intense investigations. Yet, it remains unclear to what extent condition…

Eosinophils and Lung Cancer: From Bench to Bedside Open

Anne Sibille, Jean-Louis Corhay, Renaud Louis, Vincent Ninane, Guy Jérusalem , et al. · 2022

Eosinophils are rare, multifunctional granulocytes. Their growth, survival, and tissue migration mainly depend on interleukin (IL)-5 in physiological conditions and on IL-5 and IL-33 in inflammatory conditions. Preclinical evidence support…

Combined obstructive airflow limitation associated with interstitial lung diseases (O-ILD): the bad phenotype ? Open

Julien Guiot, Monique Henket, Anne-Noëlle Frix, Fanny Gester, Marie Thys , et al. · 2022

Background Patients suffering from combined obstructive and interstitial lung disease (O-ILD) represent a pathological entity which still has to be well clinically described. The aim of this descriptive and explorative study was to describ…

Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection Open

Doriane Calmès, Sophie Graff, Nathalie Maes, Anne-Noëlle Frix, Marie Thys , et al. · 2020

Asthma and COPD are not risk factors for ICU admission and death related to SARS-CoV2 infection.

Treatment failure and hospital readmissions in severe COPD exacerbations treated with azithromycin versus placebo – a post-hoc analysis of the BACE randomized controlled trial Open

Kristina Vermeersch, Ann Belmans, Kris Bogaerts, Iwein Gyselinck, Nina Cardinaels , et al. · 2019

Background In the BACE trial, a 3-month (3 m) intervention with azithromycin, initiated at the onset of an infectious COPD exacerbation requiring hospitalization, decreased the rate of a first treatment failure (TF); the composite of treat…

Radiological and clinical specific features of anti-synthetase syndrome : a retrospective analytic study Open

Quentin Maloir, Fanny Gester, Jean-Louis Corhay, Renaud Louis, Julien Guiot · 2019

Introduction: Anti-synthetase syndrome (ASS) is a rare auto-immune disorder combining autoantibodies and specifics clinical manifestations. One of the particularities of the ASS is the pleiomorphic radiological presentation seen at …

Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis Open

Makon‐Sébastien Njock, Julien Guiot, Monique Henket, Olivier Nivelles, Marc Thiry , et al. · 2018

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of unknown aetiology which leads rapidly to death. As diagnosis of IPF is complex, we aimed to characterise microRNA (miRNA) content of exosomes from …

Methodology for Sputum Induction and Laboratory Processing Open

Julien Guiot, Sophie Demarche, Monique Henket, Virginie Paulus, Sophie Graff , et al. · 2017

The technique of sputum induction and processing is a recognized non-invasive method allowing the collection and analysis of cells from the airways, which is interesting in various respiratory diseases like asthma, chronic obstructive pulm…

The Lung Microbiome in Idiopathic Pulmonary Fibrosis: A Promising Approach for Targeted Therapies Open

Aline Fastrès, Florence Felice, Élodie Roels, Catherine Moermans, Jean-Louis Corhay , et al. · 2017

This review focuses on the role of the lung microbiome in idiopathic pulmonary fibrosis. Although historically considered sterile, bacterial communities have now been well documented in lungs both in healthy and pathological conditions. St…

Clinical experience in idiopathic pulmonary fibrosis: a retrospective study Open

Julien Guiot, Bernard Duysinx, Laurence Seidel, Monique Henket, Fanny Gester , et al. · 2017

Introduction Idiopathic pulmonary fibrosis (IPF) is a rare lung disease with an increased incidence since the last few years. Here, we report our eight-year clinical experience in CHU of Liège, Belgium. Methods We have studied retrospectiv…

Increased production of TGF-β1 from sputum cells of COPD: Relationship with airway obstruction Open

Laurent Godinas, Jean-Louis Corhay, Monique Henket, Julien Guiot, Renaud Louis , et al. · 2017

Blood Biomarkers in Idiopathic Pulmonary Fibrosis Open

Julien Guiot, Catherine Moermans, Monique Henket, Jean-Louis Corhay, Renaud Louis · 2017

Large scale multicentric studies are eagerly needed to confirm the utility of these biomarkers.

Inhaled treatment of COPD: a Delphi consensus statement Open

Vincent Ninane, Jean-Louis Corhay, Paul Germonpré, Wim Janssens, Guy Joos , et al. · 2017

Belgian and European experts recommend long-acting bronchodilators as first-choice treatment. Treatment containing ICS was found only appropriate in patients with FEV₁<50% and ≥2 moderate exacerbations or 1 severe exacerbation/y…

Le nintedanib (OFEV) : nouveau traitement remboursé dans la fibrose pulmonaire idiopathique Open

Julien Guiot, Jean-Louis Corhay, Renaud Louis · 2017

Inhaled treatment of COPD: A delphi consensus statement Open

Vincent Ninane, Jean-Louis Corhay, Paul Germonpré, Wim Janssens, Guy Joos , et al. · 2016

Vincent Ninane,1 Jean-Louis Corhay,2 Paul Germonpré,3 Wim Janssens,4 Guy F Joos,5 Giuseppe Liistro,6 Walter Vincken,7 Sandra Gurdain,8 Evelyne Vanvlasselaer,8 An Lehouck8 1Department of Respiratory Medicine, Saint-Pierre Hospital, Universi…

Yellow nail syndrome after allogeneic haematopoietic stem cell transplantation in two patients with multiple myeloma Open

Céline Gregoire, Julien Guiot, Gaëlle Vertenoeil, Évelyne Willems, Kaoutar Hafraoui , et al. · 2016

YNS after HCT might be a microvascular manifestation of endothelial GvHD and corticosteroids might be an effective treatment.

Blood eosinophil count to predict bronchial eosinophilic inflammation in COPD Open

Florence Schleich, Jean-Louis Corhay, Renaud Louis · 2016

peer reviewed

Serum Insulin - like Growth Factor B inding P rotein 2 (IGFBP2) as a m arker of Idiopathic Pulmonary F ibrosis Open

Julien Guiot, Monique Henket, Jean-Louis Corhay, Renaud Louis · 2015

Jean-Louis Corhay YOU? Author Swipe