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View article: Near Infrared Spectroscopy Versus Stump Pressure in Detecting Cerebral Ischemia During Carotid Endarterectomy: A Prospective Multicenter Observational Study
Near Infrared Spectroscopy Versus Stump Pressure in Detecting Cerebral Ischemia During Carotid Endarterectomy: A Prospective Multicenter Observational Study Open
This study found that NIRS could reduce unnecessary shunting while still having a higher sensitivity compared to SP. Additionally, it can also monitor shunt patency.
View article: A human pan-disease blood atlas of the circulating proteome
A human pan-disease blood atlas of the circulating proteome Open
The human blood proteome provides a holistic readout of health states through the assessment of thousands of circulating proteins. In this study, we present a pan-disease resource to enable the study of diverse disease phenotypes within a …
View article: Popliteal Artery Aneurysm Morphology in Symptomatic and Asymptomatic Patients Undergoing Invasive Treatment
Popliteal Artery Aneurysm Morphology in Symptomatic and Asymptomatic Patients Undergoing Invasive Treatment Open
The popliteal artery diameter did not differ between asymptomatic and symptomatic PAAs. This challenges the current clinical indication for prophylactic surgery, highlighting that diameter alone is a blunt instrument. The higher proportion…
View article: Decreasing aortic diameter and decreasing prevalence of infrarenal aortic aneurysms in a population-based screening programme
Decreasing aortic diameter and decreasing prevalence of infrarenal aortic aneurysms in a population-based screening programme Open
Background Temporal trends of infrarenal aortic diameters and their association with long-term mortality were explored in a population-based abdominal aortic aneurysm (AAA) screening programme. Additionally, changes in risk factor distribu…
View article: Towards A Resilient Healthcare: Experiential Insights on Vaccination Importance among Rural Communities in Indonesia and Philippines
Towards A Resilient Healthcare: Experiential Insights on Vaccination Importance among Rural Communities in Indonesia and Philippines Open
Background: People's perceptions of the need for COVID-19 vaccine boosters are influenced by a variety of psychosocial, demographic, and informational factors. Indonesia and Philipines data might be show difference people’s perception to r…
View article: Data Driven Models Merging Geometric, Biomechanical, and Clinical Data to Assess the Rupture of Abdominal Aortic Aneurysms
Data Driven Models Merging Geometric, Biomechanical, and Clinical Data to Assess the Rupture of Abdominal Aortic Aneurysms Open
A multiparameter estimate enhanced the purely diameter-based approach. The proposed predictability method should be further tested in longitudinal studies.
View article: Macrophage & Endometrial Receptivity
Macrophage & Endometrial Receptivity Open
Macrophages are pivotal immune cells that contribute significantly to the regulation of uterine receptivity and embryo implantation. Their ability to polarize into functionally distinct subtypes—pro-inflammatory (M1) and anti- inflammatory…
View article: Multimodal Artificial Intelligence Model for Prediction of Abdominal Aortic Aneurysm Shrinkage After Endovascular Repair ( the ART in EVAR study)
Multimodal Artificial Intelligence Model for Prediction of Abdominal Aortic Aneurysm Shrinkage After Endovascular Repair ( the ART in EVAR study) Open
Purpose: The goal of the study described in this protocol is to build a multimodal artificial intelligence (AI) model to predict abdominal aortic aneurysm (AAA) shrinkage 1 year after endovascular aneurysm repair (EVAR). Methods: In this r…
View article: Abstract 273: Evaluating Clinical Outcomes and Cost‐Effectiveness of Robotic Carotid Artery Stenting: A Multi‐Center, Propensity Score Matched Study
Abstract 273: Evaluating Clinical Outcomes and Cost‐Effectiveness of Robotic Carotid Artery Stenting: A Multi‐Center, Propensity Score Matched Study Open
Objective Preclinical studies suggest that robotic carotid artery stenting (CAS) could be superior to manual CAS. However, very limited comparative data exists comparing robotic and manual CAS patients. In addition, no data exists comparin…
View article: Anxiety and disease awareness in individuals with heredity for abdominal aortic aneurysm
Anxiety and disease awareness in individuals with heredity for abdominal aortic aneurysm Open
Objective The psychological consequences of being aware of an increased risk of developing abdominal aortic aneurysm as a first-degree relative of a person with abdominal aortic aneurysm are hitherto unexplored. This study investigates the…
View article: Sealing Zone Failure Decreases the Long Term Durability of Endovascular Aneurysm Repair
Sealing Zone Failure Decreases the Long Term Durability of Endovascular Aneurysm Repair Open
Loss of seal after EVAR is frequent and associated with post-EVAR rupture. Increased recommended sealing zones lengths and focus on sealing zones in surveillance may reduce post-EVAR ruptures and aneurysm related death.
View article: Peak wall rupture index is associated with risk of rupture of abdominal aortic aneurysms, independent of size and sex
Peak wall rupture index is associated with risk of rupture of abdominal aortic aneurysms, independent of size and sex Open
Background Information on the predictive determinants of abdominal aortic aneurysm rupture from CT angiography are scarce. The aim of this study was to investigate biomechanical parameters in abdominal aortic aneurysms and their associatio…
View article: Regulation of YAP Promotor Accessibility in Endothelial Mechanotransduction
Regulation of YAP Promotor Accessibility in Endothelial Mechanotransduction Open
BACKGROUND: Endothelial cells are constantly exposed to mechanical forces in the form of fluid shear stress, extracellular stiffness, and cyclic strain. The mechanoresponsive activity of YAP (Yes-associated protein) and its role in vascula…
View article: Prevalence of abdominal aortic aneurysm (AAA) in first-degree relatives: detecting AAA in adult offspring of AAA patients
Prevalence of abdominal aortic aneurysm (AAA) in first-degree relatives: detecting AAA in adult offspring of AAA patients Open
Background First-degree relatives of patients with abdominal aortic aneurysm (AAA) may have an increased risk of developing the disease. The primary aim was to report the prevalence of AAA in adult male and female offspring of patients wit…
View article: Merging Geometrical, Biomechanical, and Clinical Data To Assess the Rupture Risk of Abdominal Aortic Aneurysms
Merging Geometrical, Biomechanical, and Clinical Data To Assess the Rupture Risk of Abdominal Aortic Aneurysms Open
Objective: Reinforced by the latest ESVS guidelines, the maximum diameter remains almost the sole indicator for abdominal aortic aneurysm (AAA) repair. Introduced in 1999, it reflects a very conservative decision making, resulting in the e…
View article: Association of women-specific size threshold and mortality in elective abdominal aortic aneurysm repair
Association of women-specific size threshold and mortality in elective abdominal aortic aneurysm repair Open
Background It is unclear whether women derive mortality benefit from early repair of abdominal aortic aneurysms (AAA). The aim of this study was to compare short- and mid-term mortality for women treated at small versus large diameters. Me…
View article: Olfactory receptor 2 signaling drives experimental abdominal aortic aneurysm formation
Olfactory receptor 2 signaling drives experimental abdominal aortic aneurysm formation Open
Background Abdominal aortic aneurysms (AAA) are defined as enlargement above 3cm or 50% of its original diameter. Therapeutic options are limited to surgical and endovascular treatment, while no pharmacological interventions are available.…
View article: Anxiety and Disease Awareness in Adult Offspring with Heredity for Abdominal Aortic Aneurysm Detecting AAA in Adult Offspring of AAA Patients (DAAAD)
Anxiety and Disease Awareness in Adult Offspring with Heredity for Abdominal Aortic Aneurysm Detecting AAA in Adult Offspring of AAA Patients (DAAAD) Open
Objective: In the recent Detecting AAA in adult offspring of AAA patients (DAAAD) project, the prevalence of abdominal aortic aneurysm (AAA) in the general population was low, but aortic pathology was notably higher among male adult off-sp…
View article: Characteristics, Growth Rate and Diameter at Rupture of Abdominal Aortic Aneurysms Without an Intraluminal Thrombus
Characteristics, Growth Rate and Diameter at Rupture of Abdominal Aortic Aneurysms Without an Intraluminal Thrombus Open
Background: Scarce data is available on the characteristics of the small share of AAAs that do not develop an ILT.
View article: Radiation therapy for cancer is potentially associated with reduced growth of concomitant abdominal aortic aneurysm
Radiation therapy for cancer is potentially associated with reduced growth of concomitant abdominal aortic aneurysm Open
Purpose Co-prevalence of abdominal aortic aneurysm (AAA) and cancer poses a unique challenge in medical care since both diseases and their respective therapies might interact. Recently, reduced AAA growth rates were observed in cancer pati…
View article: Learning curve in open groin hernia surgery: nationwide register-based study
Learning curve in open groin hernia surgery: nationwide register-based study Open
Background Current recommendations regarding the number of open groin hernia repairs that surgical trainees are required to perform during their residency are arbitrarily defined and vary between different curricula. This register-based st…
View article: The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms
The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms Open
An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and local inflammation. This condition is often asymptomatic until rupt…