Jeanette Grundström
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View article: Size and end-group chemistry of linear polyethylene terephthalate oligomers matter in chemical risk assessment
Size and end-group chemistry of linear polyethylene terephthalate oligomers matter in chemical risk assessment Open
Cyclic and linear oligomers, formed as side-products during PET polymerization, are poorly characterized non-intentionally added substances (NIAS) in food. Risk assessment of PET oligomers is challenging due to their size, number, isomeris…
View article: Allergenic potency of various foods of mammalian origin in patients with α‐Gal syndrome
Allergenic potency of various foods of mammalian origin in patients with α‐Gal syndrome Open
Background The α‐Gal syndrome (AGS) is an emerging allergy to mammalian food caused by IgE‐mediated reactions to the carbohydrate galactose‐α‐1,3‐galactose (α‐Gal). Mammalian food sources contain α‐Gal, but the amount differs. The objectiv…
View article: The α-Gal epitope - the cause of a global allergic disease
The α-Gal epitope - the cause of a global allergic disease Open
The galactose-α-1,3-galactose (α-Gal) epitope is the cause of a global allergic disease, the α-Gal syndrome (AGS). It is a severe form of allergy to food and products of mammalian origin where IgE against the mammalian carbohydrate, α-Gal,…
View article: Th2-skewed T cells correlate with B cell response to α-Gal and tick antigens in α-Gal syndrome
Th2-skewed T cells correlate with B cell response to α-Gal and tick antigens in α-Gal syndrome Open
Tick bites have been shown to transmit a novel form of severe food allergy, the galactose-α-1,3-galactose (α-Gal) syndrome (AGS). Cellular responses to α-Gal in patients with AGS have, to date, not been thoroughly scrutinized. Therefore, w…
View article: Cross‐reactivity between tick and wasp venom can contribute to frequent wasp sensitization in patients with the α‐Gal syndrome
Cross‐reactivity between tick and wasp venom can contribute to frequent wasp sensitization in patients with the α‐Gal syndrome Open
Background α‐Gal syndrome (AGS) is a food allergy with severe delayed allergic reactions, mediated by IgE‐reactivity to galactose‐α1,3‐galactose (α‐Gal). AGS is strongly associated with tick bites. An increased incidence of venom sensitiza…
View article: Course of IgE to α‐Gal in a Swedish population of α‐Gal syndrome patients
Course of IgE to α‐Gal in a Swedish population of α‐Gal syndrome patients Open
Course of IgE to α-Gal in a Swedish population of α-Gal syndrome patientsTo the Editor, The α-Gal syndrome (AGS) is a severe form of food allergy which has increased worldwide for the past decade.It is caused by IgE antibodies to the carbo…
View article: Bovine γ‐globulin, lactoferrin, and lactoperoxidase are relevant bovine milk allergens in patients with α‐Gal syndrome
Bovine γ‐globulin, lactoferrin, and lactoperoxidase are relevant bovine milk allergens in patients with α‐Gal syndrome Open
Background Mammalian meat is the most common trigger of the allergic reactions in patients with α‐Gal syndrome (AGS). Milk and dairy, although less often, also cause a significant number of allergic manifestations. The aim of this study wa…
View article: Elucidating the α‐Gal syndrome at the molecular allergen level
Elucidating the α‐Gal syndrome at the molecular allergen level Open
The galactose-α-1,3-galactose (α-Gal) syndrome (AGS) is a novel food allergy with delayed severe allergic reactions after mammalian meat consumption, caused by IgE against the carbohydrate epitope α-Gal present in mammalian products. We ha…
View article: Alpha-Gal on the Protein Surface Hampers Transcytosis through the Caco-2 Monolayer
Alpha-Gal on the Protein Surface Hampers Transcytosis through the Caco-2 Monolayer Open
Transepithelial transport of proteins is an important step in the immune response to food allergens. Mammalian meat allergy is characterized by an IgE response against the carbohydrate moiety galactosyl-α-1,3-galactose (α-Gal) present on m…
View article: Clinical and Serological Characterization of the α-Gal Syndrome—Importance of Atopy for Symptom Severity in a European Cohort
Clinical and Serological Characterization of the α-Gal Syndrome—Importance of Atopy for Symptom Severity in a European Cohort Open
AGS is an upcoming food allergy where patients report severe symptoms and tick bites. Atopy was found to affect the manifestation of the disease in Swedish patients.
View article: Supplementary Material for: Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics
Supplementary Material for: Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics Open
Background: Selective inhibition of cyclooxygenase-2 (COX-2) reduces the production of prostaglandin E2 (PGE2), which can have both pro- and anti-inflammatory effects on allergic inflammation. Moreover, in vitro PGE2 has been shown to affe…
View article: Supplementary Material for: Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics
Supplementary Material for: Selective COX-2 Inhibition Exerts No Negative Effects on Peripheral Blood Lymphocytes in Allergic Asthmatics Open
Background: Selective inhibition of cyclooxygenase-2 (COX-2) reduces the production of prostaglandin E2 (PGE2), which can have both pro- and anti-inflammatory effects on allergic inflammation. Moreover, in vitro PGE2 has been shown to affe…