Explanipedia

Dedicated AI Expert System vs Generative AI With Large Language Model for Clinical Diagnoses Open

Mitchell J. Feldman, Edward P. Hoffer, Jared Conley, Jaime Chang, Jeanhee Chung , et al. · 2025

Importance Large language models (LLMs) have not yet been compared with traditional diagnostic decision support systems (DDSSs) on unpublished clinical cases. Objective To compare the performance of 2 widely used LLMs (ChatGPT, version 4 […

Healthcare experiences of patients with Down syndrome from primarily Spanish‐speaking households Open

Jeanhee Chung, Kavita Krell, Albert Pless, Carie Michael, Amy Torres , et al. · 2023

We report on the health care experiences of individuals with Down syndrome (DS) from families who are primarily Spanish‐speaking. Data were collected through three methods: (1) a nationally distributed, 20‐item survey, (2) two focus groups…

Views on the impact of the <span>COVID</span>‐19 pandemic on health in people with Down syndrome from diverse backgrounds Open

Stephanie L. Santoro, Sandra Baker, Jasmine M. Blake, Maria J. Cabrera, Kelli Caughman , et al. · 2023

Down syndrome (DS) has a unique medical and psychological profile. To date, few studies have asked individuals with DS about their views of health, and fewer have explored the impact of COVID‐19 on the health of individuals with DS and the…

Healthcare experiences of patients with Down syndrome who are Black, African American, of African descent, or of mixed race Open

Kavita Krell, Albert Pless, Carie Michael, Amy Torres, Jeanhee Chung , et al. · 2022

Scant research has explored the healthcare experiences of people with Down syndrome (DS) in the United States who are Black, African American, of African descent, or of mixed race. The purpose of this study was to identify and describe the…

Researcher Perceptions of a Self-Service Online Portal to Facilitate Volunteer Recruitment into Clinical Trials Open

Srinivas Emani, Yichuan Grace Hsieh, Greg Estey, Holly M. Parker, Xiaofeng Zhang , et al. · 2021

Background Recruitment of volunteers is a major challenge for clinical trials. There has been increasing development and use of Internet-based portals in recruitment for clinical research. There has been little research on researcher use a…

Assessment of Stakeholder Engagement in a Down Syndrome Research Study Open

Jeanhee Chung, Ashwini Sarathy, Yichuan Grace Hsieh, Greg Estey, Amy Torres , et al. · 2021

There is growing recognition of the importance of engaging patients early in the design of research studies. For studies involving patients with intellectual and cognitive disabilities, researchers may consider engaging with family caregiv…

Correction: A randomized controlled trial of an online health tool about Down syndrome Open

Jeanhee Chung, Karen Donelan, Eric A. Macklin, Alison Schwartz, Ibrahim Elsharkawi , et al. · 2020

Does a Web-Based Platform for Caregivers Help People with Down Syndrome Get Recommended Health Services? Open

Jeanhee Chung, Karen Donelan, Eric A. Macklin, Alison Schwartz, Ibrahim Elsharkawi , et al. · 2020

What were the limits of the study?Most caregivers in the study were white and had college degrees.Findings may differ for caregivers from other backgrounds.Future research could test DSC2U with people from other backgrounds. How can people…

A randomized controlled trial of an online health tool about Down syndrome Open

Lisa Majewski, Jawanda Mast, Melissa Skavlem, Jeanhee Chung, Karen Donelan , et al. · 2020

Impact of COVID-19 on Public Research Recruitment Open

Yichuan Grace Hsieh, Holly Parker, Greg Estey, Stephen Lorenz, Mark Wylie , et al. · 2020

The coronavirus disease 2019 (COVID-19) pandemic created a major challenge for clinical trials recruitment as early attention was focused on matters of public health and clinical care, and research--outside of COVID-19-- essentially shut d…

Accuracy of self-reported history of autoimmune disease: A pilot study Open

Julia A. O’Rourke, Caitlin Ravichandran, Yamini J. Howe, Jennifer Mullett, Christopher J. Keary , et al. · 2019

Research associating the increased prevalence of familial autoimmunity with neuropsychiatric disorders is reliant upon the ascertainment of history of autoimmune diseases from relatives. To characterize the accuracy of self-report, we comp…

The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability Open

Jeanhee Chung, Daniel E. Bauer, Alireza Ghamari, Christopher P. Nizzi, Kathryn M. Deck , et al. · 2015

In multicellular organisms, the mechanisms by which diverse cell types acquire distinct amino acids and how cellular function adapts to their availability are fundamental questions in biology. We found that increased neutral essential amin…

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