Jeanna Yu
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View article: A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design
A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design Open
Distinct CD4+ T cell epitopes have been associated with spontaneous control of HIV-1 replication, but analysis of antigen-dependent factors that influence epitope selection is lacking. To examine these factors, we used a cell-free antigen …
View article: TCR-mimic bispecific antibodies to target the HIV-1 reservoir
TCR-mimic bispecific antibodies to target the HIV-1 reservoir Open
Significance Novel approaches to promote killing of HIV-1–infected cells are necessary for elimination of the latent reservoir, the main barrier to a cure. Here, we utilized a diverse phage-display library to construct T cell receptor (TCR…
View article: A Cell-Free Antigen Processing System Reveals Factors Critical for HIV-1 Epitope Dominance and Informs Vaccine Design
A Cell-Free Antigen Processing System Reveals Factors Critical for HIV-1 Epitope Dominance and Informs Vaccine Design Open