Explanipedia

Exploring COVID-19 vaccine attitudes among pregnant women: key factors and strategies to enhance uptake Open

Maclaine A. Parish, Sneh Lata Badhwar, Jeanne S. Sheffield, Sabra L. Klein · 2025

Pregnancy reduces COVID-19 vaccine immunity against novel variants Open

Maclaine A. Parish, Jaiprasath Sachithanandham, L. Gutiérrez, Han-Sol Park, Anna Yin , et al. · 2025

Pregnant women are at heightened risk for severe outcomes from infectious diseases like COVID-19, yet were not included in initial vaccine trials, which may contribute to low booster uptake (15% or lower). We explored the serological and c…

PRenatal mOdulator treatment to PrEvent CF complicaTions (PROTECT) workshop report Open

Sylvia Szentpetery, Dara Riva, Yair J. Blumenfeld, John F. Engelhardt, Carmen Luna‐Paredes , et al. · 2025

Teratogenic Risk Impact Mitigation (TRIM): Development of Explicit Criteria to Facilitate Decisions Regarding Teratogenic Risk Mitigation Strategies Open

Celeste L. Y. Ewig, Yanning Wang, Nicole E. Smolinski, Gita A. Toyserkani, Cynthia LaCivita , et al. · 2025

Pregnancy Reduces COVID-19 Vaccine Immunity Against Novel Variants Open

Maclaine A. Parish, Jaiprasath Sachithanandham, L. Gutiérrez, Han-Sol Park, Anna Yin , et al. · 2025

Pregnant women are at heightened risk for severe outcomes from infectious diseases like COVID-19, yet were not included in initial vaccine trials, which may contribute to low booster uptake (15% or lower). We explored the serological and c…

Infant feeding for people living with HIV in high resource settings: a multi-disciplinary approach with best practices to maximise risk reduction Open

Anna Powell, Mary Ann Knott-Grasso, Jean Anderson, Alison Livingston, Nadine Rosenblum , et al. · 2023

Shared decision making for infant feeding in the context of HIV in high-resourced settings is necessary to acknowledge patient autonomy, meet increasing patient requests and address the changing reality of perinatal HIV care. In low-to mid…

Findings From Severe Maternal Morbidity Surveillance and Review in Maryland Open

Carrie Wolfson, Jiage Qian, Pamela Chin, Cathy Downey, Katie Jo Mattingly , et al. · 2022

Importance In the US, more than 50 000 women experience severe maternal morbidity (SMM) each year, and the SMM rate more than doubled during the past 25 years. In response, professional organizations called for birthing facilities to routi…

Long-Term Fine Particulate Matter Concentrations and Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2: Differential Relationships by Socioeconomic Status Among Pregnant Individuals in New York City Open

Joan A. Casey, Marianthi‐Anna Kioumourtzoglou, Elizabeth L. Ogburn, Alexander Melamed, Jeffrey Shaman , et al. · 2022

We aimed to determine whether long-term ambient concentrations of fine particulate matter (particulate matter with an aerodynamic diameter less than or equal to 2.5 μm (PM2.5)) were associated with increased risk of testing positive for co…

Multi-site observational maternal and infant COVID-19 vaccine study (MOMI-vax): a study protocol Open

Flor M. Muñoz, Richard H. Beigi, Christine M. Posavad, Barbra A. Richardson, Helen Y. Chu , et al. · 2022

Erratum to: Experience and Outcomes of Breastfed Infants of Women Living with HIV in the United States: Findings from a Single Center Breastfeeding Support Initiative Open

Hasiya Yusuf, Mary Ann Knott-Grasso, Jean Anderson, Alison Livingston, Nadine Rosenblum , et al. · 2022

Experience and Outcomes of Breastfed Infants of Women Living With HIV in the United States: Findings From a Single-Center Breastfeeding Support Initiative Open

Hasiya Yusuf, Mary Ann Knott-Grasso, Jean Anderson, Alison Livingston, Nadine Rosenblum , et al. · 2021

We assessed breastfeeding outcomes for a cohort of infants born to women living with HIV (WLHIV) at an urban health care center in the United States. Ten infants were exclusively breastfed for a mean duration of 4.4 (1.0-8.6) months. All h…

Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection Open

Morgan L. Sherer, Jun Lei, Patrick S. Creisher, Minyoung Jang, Ramya Reddy , et al. · 2021

Global equity in protection of pregnant frontline workers Open

Elana Jaffe, Ruth A. Karron, Carleigh Krubiner, Chizoba Wonodi, Richard H. Beigi , et al. · 2021

Vaccination of frontline workers against COVID-19 is underway in some countries. With women comprising a majority of health, education, and other essential workforces, many on the front lines of the pandemic response will be pregnant at th…

Dysregulated immunity in SARS-CoV-2 infected pregnant women Open

Morgan L. Sherer, Jun Lei, Patrick S. Creisher, Minyoung Jang, Ramya Reddy , et al. · 2020

Importance The effects of SARS-CoV-2 infection on immune responses during pregnancy have not been systematically evaluated. Objective To assess the impact of SARS-CoV-2 infection during pregnancy on inflammatory and humoral responses in ma…

Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019 Open

Richard M. Burwick, Sigal Yawetz, Kathryn E. Stephenson, Ai‐ris Y. Collier, Pritha Sen , et al. · 2020

Background Remdesivir is efficacious for severe coronavirus disease 2019 (COVID-19) in adults, but data in pregnant women are limited. We describe outcomes in the first 86 pregnant women with severe COVID-19 who were treated with remdesivi…

Tenofovir alafenamide use in pregnant and lactating women living with HIV Open

Ahizechukwu C. Eke, Kristina M. Brooks, Rahel D. Gebreyohannes, Jeanne S. Sheffield, Kelly E. Dooley , et al. · 2020

Introduction: Tenofovir alafenamide (TAF)-containing fixed-dose drug combinations (FDCs) are increasingly being used in managing pregnant women living with HIV. However, TAF is not currently recommended during pregnancy due to limit…

Roundtable Discussion on COVID-19 Through a Sex and Gender Lens Open

Marianne J. Legato, Wendy L. Bennett, Sabra L. Klein, Jeanne S. Sheffield, Rosemary Morgan , et al. · 2020

Although the full and lasting impact of the coronavirus disease 2019 (COVID-19) outbreak is yet to be determined, there is evidence that sex and gender play a significant role in determining patient outcomes across the globe. This roundtab…

1180: Development of an obstetric hemorrhage response intervention: The postpartum hemorrhage cart Open

Benjamin K. Kogutt, Susan E. Brown Will, Janis Ferrell, Jeanne S. Sheffield · 2019

893: Levels of maternal care and indications for transport Open

Benjamin K. Kogutt, Bernard D. Morris, Jeremy Applebaum, Valerie G Hall, Michelle Phillips , et al. · 2019

Pregnant women & vaccines against emerging epidemic threats: Ethics guidance for preparedness, research, and response Open

Carleigh Krubiner, Ruth Faden, Ruth A. Karron, Margaret Olivia Little, Anne Drapkin Lyerly , et al. · 2019

Pharmacologic Research in Pregnant Women — Time to Get It Right Open

Ahizechukwu C. Eke, Kelly E. Dooley, Jeanne S. Sheffield · 2019

Facilitating inclusion of pregnant women in clinical research could help answer important questions about the effects of medication use during pregnancy and the ways in which pregnancy alters pharmacokinetics and drug effects.

IL-1 receptor antagonist therapy mitigates placental dysfunction and perinatal injury following Zika virus infection Open

Jun Lei, Meghan S. Vermillion, Bei Jia, Han Xie, Li Xie , et al. · 2019

Zika virus (ZIKV) infection during pregnancy causes significant adverse sequelae in the developing fetus, and results in long-term structural and neurologic defects. Most preventive and therapeutic efforts have focused on the development o…

17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy Open

Ahizechukwu C. Eke, Jeanne S. Sheffield, Ernest M. Graham · 2019

OBJECTIVE: To evaluate whether 17α-hydroxyprogesterone caproate use in preventing preterm birth increases the risk of gestational diabetes mellitus (GDM). DATA SOURCES: Electronic databases (MEDLINE, Scopus, ClinicalTrials.gov, PROSPERO, E…

Simulation of a Spontaneous Vaginal Delivery and Neonatal Resuscitation in a Biocontainment Unit Open

Benjamin K. Kogutt, Jeanne S. Sheffield, Dianne Whyne, Lisa L. Maragakis, Jennifer Andonian , et al. · 2019

This article describes a large-scale scenario designed to test the capabilities of a US biocontainment unit to manage a pregnant woman infected with a high-consequence pathogen, and to care for a newborn following labor and spontaneous vag…

Adjuvant 17-hydroxyprogesterone caproate in women withultrasound-indicated cerclage: a systematic review and meta-analysis Open

Katie Lichter, Jeanne S. Sheffield, Ernest M. Graham, Ahizechukwu C. Eke · 2019

Objective: To assess the additional benefits of 17-hydroxyprogesterone caproate (17-OHPC) therapy in preventing recurrent spontaneous preterm birth in women with an ultrasound-indicated cerclage.Methods: Electronic databases …

Detecting Patterns of Prescription Drug Use During Pregnancy and Lactation with Visualization Techniques. Open

Ou Stella Liang, Jeanne S. Sheffield, Casey Overby Taylor · 2019

Visualization of administrative claims data can quickly detect temporal patterns of prescription drug use during pregnancy and lactation.

Single versus Double-Balloon Transcervical Catheter for Labor Induction: A Systematic Review and Meta-Analysis Open

Samantha X. de los Reyes, Jeanne S. Sheffield, Ahizechukwu C. Eke · 2018

Objective To evaluate for difference in outcomes between single- and double-balloon catheters for labor induction. Study Design We searched CINAHL, Embase, Cochrane Register, MEDLINE, ISI Web of Sciences, LILACs, and Google Scholar and ret…

Adjuvant 17‐hydroxyprogesterone caproate in women with history‐indicated cerclage: A systematic review and meta‐analysis Open

Ahizechukwu C. Eke, Jeanne S. Sheffield, Ernest M. Graham · 2018

Introduction The purpose of this study was to evaluate whether there are additional benefits of 17‐hydroxyprogesterone caproate (17‐ OHPC ) supplementation in preventing recurrent spontaneous preterm birth in women with a prophylactic cerc…

Complete Placenta Previa: Ultrasound Biometry and Surgical Outcomes Open

Alison Wortman, Stephanie Schaefer, Donald D. McIntire, Jeanne S. Sheffield, Diane M. Twickler · 2018

Objective To evaluate the relationship between surgical outcomes and ultrasound measurement of placental extension beyond the cervical os in women with placenta previa. Study Design This is a retrospective cohort study of singleton pregnan…

858: Integrase inhibitor versus protease inhibitor (PI)-based antiretroviral therapy (ART) in late pregnancy and rapid HIV viral load reduction in ART naïve patients: Cost effectiveness analysis Open

Ahizechukwu C. Eke, Kelly E. Dooley, Jeanne S. Sheffield · 2018

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