Jeea Choi
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View article: Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation Open
The transcription factor NFATC2 induces β cell proliferation in mouse and human islets. However, the genomic targets that mediate these effects have not been identified. We expressed active forms of Nfatc2 and Nfatc1 in human islets. By in…
View article: Additional file 2: Table S1. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 2: Table S1. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of genes used in Fig. 1c for hierarchical clustering. (XLSX 30 kb)
View article: Additional file 9: Table S8. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 9: Table S8. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of the DNA oligos and qPCR assays used in this study. (XLSX 32 kb)
View article: Additional file 8: Table S7. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 8: Table S7. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of the antibodies used in this study. (XLSX 43 kb)
View article: Additional file 7: Table S6. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 7: Table S6. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of kernel signals for Wave-Crest simulation studies. (XLSX 21 kb)
View article: Additional file 10: Table S9. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 10: Table S9. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of the siRNA used in this study. (XLSX 46 kb)
View article: Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional properties
Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional properties Open
Astrocytes display diverse morphologies in different regions of the central nervous system. Whether astrocyte diversity is attributable to developmental processes and bears functional consequence, especially in humans, is unknown. RNA sequ…
View article: Additional file 6: Table S5. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 6: Table S5. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of the top 150 genes identified by Wave-Crest fishing step. (XLSX 56 kb)
View article: Additional file 4: Table S3. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 4: Table S3. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of SCPattern identified stage-specific 3247 genes. (XLSX 167 kb)
View article: Additional file 5: Table S4. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 5: Table S4. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of 2178 genes used for Wave-Crest fishing step. (XLSX 54 kb)
View article: Additional file 3: Table S2. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm
Additional file 3: Table S2. of Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm Open
List of the GO terms by Allez enrichment analysis. (XLSX 62 kb)
View article: SCPattern: A statistical approach to identify and classify expression changes in single cell RNA-seq experiments with ordered conditions
SCPattern: A statistical approach to identify and classify expression changes in single cell RNA-seq experiments with ordered conditions Open
Motivation With the development of single cell RNA-seq (scRNA-seq) technology, scRNA-seq experiments with ordered conditions (e.g. time-course) are becoming common. Methods developed for analyzing ordered bulk RNA-seq experiments are not a…
View article: OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data
OEFinder: a user interface to identify and visualize ordering effects in single-cell RNA-seq data Open
Summary: A recent article identified an artifact in multiple single-cell RNA-seq (scRNA-seq) datasets generated by the Fluidigm C1 platform. Specifically, Leng et al. showed significantly increased gene expression in cells captured from si…