Jeeven S. Solanki
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View article: COMPUTER AIDED DRUG DESIGN: A PARADIGM SHIFT TO RATIONAL DRUG DESIGN (A CASE STUDY OF ALZHEIMER’S DRUG INTERPIRDINE FAILURE)
COMPUTER AIDED DRUG DESIGN: A PARADIGM SHIFT TO RATIONAL DRUG DESIGN (A CASE STUDY OF ALZHEIMER’S DRUG INTERPIRDINE FAILURE) Open
Drug discovery and design is a tedious and lengthy process which takes enormous time, andwhen this process reaches it’s final stage that is the final stage of clinical trials 90% of thepromising drug candidates fail levying a huge financia…
View article: BIOLOGICAL EVALUATION OF GLYCOGEN SYNTHASE KINASE-3 Β INHIBITORS AS ANTIDIABETIC AGENT
BIOLOGICAL EVALUATION OF GLYCOGEN SYNTHASE KINASE-3 Β INHIBITORS AS ANTIDIABETIC AGENT Open
A series of phenylmethylenehydantoin and phenylmethylenerhodanine derivatives (Der 1 toDer 8) were synthesized. These newly synthesized derivatives have been characterized byelemental analysis molecular weight measurements as well as spect…
View article: Computer Aided Drug Design: A Paradigm Shift To Rational Drug Design (A Case Study Of Alzheimer'S Drug Interpirdine Failure)
Computer Aided Drug Design: A Paradigm Shift To Rational Drug Design (A Case Study Of Alzheimer'S Drug Interpirdine Failure) Open
Drug discovery and design is a tedious and lengthy process which takes enormous time, and when this process reaches it’s final stage that is the final stage of clinical trials 90% of the promising drug candidates fail levying a…
View article: Biological Evaluation Of Glycogen Synthase Kinase-3 Β Inhibitors As Antidiabetic Agent
Biological Evaluation Of Glycogen Synthase Kinase-3 Β Inhibitors As Antidiabetic Agent Open
A series of phenylmethylenehydantoin and phenylmethylenerhodanine derivatives (Der 1 to Der 8) were synthesized. These newly synthesized derivatives have been characterized by elemental analysis molecular weight measurements as…
View article: ZIKA VIRUS SERENE PROTEASE COMPLEX (NS2B-NS3) INHIBITION BY 2-AMINO-5-{[(1Z)-AMINO({[(Z)-BENZOYL]IMINO})METHYL]AMINO}-N-(5-AMINO-7-{[CARBAMOYL(PHENYL)METHYL]AMINO}-6-OXOHEPTYL)PENTANAMIDE, IN SILICO STUDIES
ZIKA VIRUS SERENE PROTEASE COMPLEX (NS2B-NS3) INHIBITION BY 2-AMINO-5-{[(1Z)-AMINO({[(Z)-BENZOYL]IMINO})METHYL]AMINO}-N-(5-AMINO-7-{[CARBAMOYL(PHENYL)METHYL]AMINO}-6-OXOHEPTYL)PENTANAMIDE, IN SILICO STUDIES Open
Objective: The present in silico study is taken to report 2-amino-5-{[(1Z) -amino ({[(Z) -benzoyl] imino}) methyl] amino} -N-(5-amino-7-{[carbamoyl (phenyl) methyl] amino} -6-oxoheptyl) pentanamide as Zika virus (ZIKV) NS2B-NS3 protease in…