Jeff A. Newcomb
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View article: Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial
Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial Open
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on H…
View article: A Provider‐Based Approach to Address Racial Disparities in Lupus Clinical Trial Participation
A Provider‐Based Approach to Address Racial Disparities in Lupus Clinical Trial Participation Open
OBJECTIVE: Substantial disparities exist in clinical trial participation, which is problematic in diseases such as lupus that disproportionately affect racial/ethnic minority populations. Our objective was to examine the effectiveness of a…
View article: Comparison of Gout Flares With the Initiation of Treat‐to‐Target Allopurinol and Febuxostat: A Post‐Hoc Analysis of a Randomized Multicenter Trial
Comparison of Gout Flares With the Initiation of Treat‐to‐Target Allopurinol and Febuxostat: A Post‐Hoc Analysis of a Randomized Multicenter Trial Open
Objective Initiating urate‐lowering therapy (ULT) in gout can precipitate arthritis flares. There have been limited comparisons of flare risk during the initiation and escalation of allopurinol and febuxostat, administered as a treat‐to‐ta…
View article: Determinants of Achieving Serum Urate Goal with <scp>Treat‐to‐Target Urate‐Lowering</scp> Therapy in Gout
Determinants of Achieving Serum Urate Goal with <span>Treat‐to‐Target Urate‐Lowering</span> Therapy in Gout Open
Objective Using trial data comparing treat‐to‐target allopurinol and febuxostat in gout, we examined participant characteristics associated with serum urate (SU) goal achievement. Methods Participants with gout and SU ≥6.8 mg/dL were rando…
View article: Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management
Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management Open
Allopurinol and febuxostat achieved serum urate goals in patients with gout; allopurinol was noninferior to febuxostat in controlling flares. Similar outcomes were noted in participants with stage 3 chronic kidney disease. (Funded by the C…