Jeffrey A. Golden
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View article: Mind the gap: a quality improvement study to determine health care value of rapid-access telemedicine addiction treatment in recently incarcerated individuals
Mind the gap: a quality improvement study to determine health care value of rapid-access telemedicine addiction treatment in recently incarcerated individuals Open
View article: Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics
Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics Open
View article: A community-led initiative to de-risk and advance Parkinson’s disease therapeutic targets
A community-led initiative to de-risk and advance Parkinson’s disease therapeutic targets Open
View article: Correction to “Community gun violence prevention” The Lancet Regional Health—Americas volume 43, 100990, March 2025
Correction to “Community gun violence prevention” The Lancet Regional Health—Americas volume 43, 100990, March 2025 Open
View article: Community gun violence prevention
Community gun violence prevention Open
A pathology foundation model for cancer diagnosis and prognosis prediction Open
View article: Small airway brush gene expression predicts chronic lung allograft dysfunction and mortality
Small airway brush gene expression predicts chronic lung allograft dysfunction and mortality Open
View article: A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis
A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis Open
Reciprocal interactions between alveolar fibroblasts and epithelial cells are crucial for lung homeostasis, injury repair, and fibrogenesis, but underlying mechanisms remain unclear. To investigate, we administered the fibroblast-selective…
View article: Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Clinical Trial
Bexotegrast in Patients with Idiopathic Pulmonary Fibrosis: The INTEGRIS-IPF Clinical Trial Open
Rationale: Idiopathic pulmonary fibrosis (IPF) is a rare and progressive disease that causes progressive cough, exertional dyspnea, impaired quality of life, and death. Objectives: Bexotegrast (PLN-74809) is an oral, once-dai…
View article: ARX regulates cortical interneuron differentiation and migration
ARX regulates cortical interneuron differentiation and migration Open
Mutations in aristaless-related homeobox ( ARX ) are associated with neurodevelopmental disorders including developmental epilepsies, intellectual disabilities, and autism spectrum disorders, with or without brain malformations. Aspects of…
View article: <i>MICB</i> Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death
<i>MICB</i> Genomic Variant Is Associated with NKG2D-mediated Acute Lung Injury and Death Open
Rationale: Acute lung injury (ALI) carries a high risk of mortality but has no established pharmacologic therapy. We previously found that experimental ALI occurs through natural killer (NK) cell NKG2D receptor activation and that t…
View article: CCR5 drives NK cell–associated airway damage in pulmonary ischemia-reperfusion injury
CCR5 drives NK cell–associated airway damage in pulmonary ischemia-reperfusion injury Open
Primary graft dysfunction (PGD) limits clinical benefit after lung transplantation, a life-prolonging therapy for patients with end-stage disease. PGD is the clinical syndrome resulting from pulmonary ischemia-reperfusion injury (IRI), dri…
View article: Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction
Short airway telomeres are associated with primary graft dysfunction and chronic lung allograft dysfunction Open
View article: Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis
Decreased Lymphocytic Bronchitis Severity in the Era of Azithromycin Prophylaxis Open
Background. Large-airway lymphocytic inflammation (LB), assessed on endobronchial biopsies, has been associated with acute cellular rejection and chronic lung allograft dysfunction (CLAD). Azithromycin (AZI) prophylaxis has been used to pr…
View article: A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis
A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis Open
Reciprocal interactions between alveolar fibroblasts and epithelial cells are crucial for lung homeostasis, injury repair, and fibrogenesis, but underlying mechanisms remain unclear. To investigate this, we administered the fibroblast-sele…
View article: Biofire pneumonia panel in lung donors: faster detection but limited pathogens
Biofire pneumonia panel in lung donors: faster detection but limited pathogens Open
Background Culture of bronchoalveolar lavage (BAL) specimens takes time to report. We tested whether a molecular diagnostic test could accelerate donor lung assessment and treatment. Methods We compared BioFire Film Array Pneumonia Panel (…
View article: Machine learning for cryosection pathology predicts the 2021 WHO classification of glioma
Machine learning for cryosection pathology predicts the 2021 WHO classification of glioma Open
View article: Supplementary Figures from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Figures from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Figure S1, Figure S2, Figure S3, Figure S4, Figure S5
View article: Supplementary Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Supplementary legends
View article: Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Purpose:Histopathology evaluation is the gold standard for diagnosing clear cell (ccRCC), papillary, and chromophobe renal cell carcinoma (RCC). However, interrater variability has been reported, and the whole-slide histopathology images l…
View article: Supplementary Figures from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Figures from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Figure S1, Figure S2, Figure S3, Figure S4, Figure S5
View article: Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Purpose:Histopathology evaluation is the gold standard for diagnosing clear cell (ccRCC), papillary, and chromophobe renal cell carcinoma (RCC). However, interrater variability has been reported, and the whole-slide histopathology images l…
View article: Supplementary Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Data from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Supplementary legends
View article: Supplementary Materials from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Materials from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Supplementary Materials
View article: Supplementary Materials from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma
Supplementary Materials from Development of a Histopathology Informatics Pipeline for Classification and Prediction of Clinical Outcomes in Subtypes of Renal Cell Carcinoma Open
Supplementary Materials
View article: Development of the Lung Transplant Frailty Scale (LT-FS)
Development of the Lung Transplant Frailty Scale (LT-FS) Open
View article: Subphenotypes of frailty in lung transplant candidates
Subphenotypes of frailty in lung transplant candidates Open
View article: TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system
TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system Open
Sonic hedgehog signaling regulates processes of embryonic development across multiple tissues, yet factors regulating context-specific Shh signaling remain poorly understood. Exome sequencing of families with polymicrogyria (disordered cor…
View article: Frailty and genetic risk predict fracture after lung transplantation
Frailty and genetic risk predict fracture after lung transplantation Open
View article: CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction
CD16+ natural killer cells in bronchoalveolar lavage are associated with antibody-mediated rejection and chronic lung allograft dysfunction Open